2020 American Transplant Congress
Evaluation of the Safety and Tolerability of Clazakizumab® as a Desensitization Agent in Highly-HLA Sensitized ESRD Patients (NCT03380962): 12m Follow-Up
*Purpose: IL-6 mediates inflammation and activation of T-cells, B-cells & plasma cells. Thus, IL-6 may represent an important target for desensitization (DES). Here we report…2020 American Transplant Congress
The Significance of Donor Gender on Graft Survival and Histological Ischemia Reperfusion Injury in Liver Transplant Patients
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Experimental animal models have demonstrated improved ability of females (F) to recover from ischemia-reperfusion injury (IRI) compared with males (M). Recent work combining human…2020 American Transplant Congress
Mycophenolic Acid Exposure in Young, Middle Age and Older Stable Renal Transplant Recipients
*Purpose: Mycophenolic acid (MPA) is an essential drug in maintenance immunosuppressive regimens. In spite of increased kidney transplants in the elderly, limited pharmacokinetic investigations comparing…2020 American Transplant Congress
Torque Teno Virus for Risk Stratification of Graft Rejection and Infection in Kidney Transplant Recipients – A Prospective Observational Trial
Medical University Vienna, Vienna, Austria
*Purpose: The non-pathogenic and ubiquitous Torque Teno virus (TTV) is associated with immunosuppression in solid organ transplant recipients. This trial was designed to assess the…2020 American Transplant Congress
Type 1 Innate Lymphoid Cells Are Critical Pro-Inflammatory Effector Cells in a Fatty Liver Mouse Model of Ischemia-Reperfusion Injury
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis and immune regulation through the activation…2020 American Transplant Congress
Preformed Anti-HLA Donor-Specific Antibodies Immunological Risk Assessment: The Importance of HLA Antibody Locus-Specificity
*Purpose: The screening of preformed donor-specific HLA antibodies (pfDSA) by single antigen bead assays has increased the complexity of pre-transplant patient risk stratification. We evaluated…2020 American Transplant Congress
Paired-Donor Kidney Exchange Has Comparable Early Graft Function to Directed Living Donor
Transplant Surgery, University of Virginia, Charlottesville, VA
*Purpose: Living kidney donation in the United States is associated with improved graft and patient survival. However, there is minimal data on graft function in…2020 American Transplant Congress
Impact of Enhanced Recovery after Surgery Protocols on Robotic Living Kidney Donor Outcomes: A Single Center Experience
Virginia Commonwealth University, Richmond, VA
*Purpose: Traditional management of living donor nephrectomies includes intraoperative volume loading to maintain renal perfusion and urine output. Recently our center initiated fluid restriction as…2020 American Transplant Congress
Characterization of Use and Safety of Non-Insulin Agents for Management of Post-Transplant Diabetes Mellitus in the Kidney Transplant Population
*Purpose: Newer, non-insulin agents appear to have significant cardiovascular benefits. However, use of these agents for diabetes (DM) management in kidney transplant recipients (KTR) has…2020 American Transplant Congress
Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus in Pediatric Population: UNOS Data Set
*Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…
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