2020 American Transplant Congress
Role of Innate Allorecognition Pathways in Mouse Kidney and Heart Allograft Rejection
*Purpose: Paired immunoglobulin-like receptors (PIR) and CD47 are molecules expressed on host myeloid cells. They recognize donor polymorphic MHC and signal regulatory protein alpha (SIRPα),…2020 American Transplant Congress
An Evaluation of Deceased Donor Eligibility and US Organ Donation Rates
*Purpose: Organ Procurement Organization (OPO) performance assessment is essential for identifying best practices and improvement opportunities. We aimed to evaluate OPO performance using the following…2020 American Transplant Congress
The Urine Qisant Score: Non-Invasive, Accurate, Diagnosis and Prediction of Kidney Transplant Rejection
*Purpose: Accurate and non-invasive monitoring of renal allografts post-transplant is essential for early detection of acute rejection (AR) and to directly impact the long-term survival…2020 American Transplant Congress
Factors Predicting Outcome after Living Donor Liver Transplantation in the Era of Intra-Operative Flow Measurements and Inflow Modulation
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To identify pre/intra-operative factors which predict adverse outcome after living donor liver transplantation (LDLT).*Methods: All patients who underwent first LDLT at UPMC, Pittsburgh from…2020 American Transplant Congress
Racial Disparities in Liver Transplant Outcomes Are Consistent Regardless of Transplant Center Characteristics in the United States
Emory University, Emory Transplant Center, Atlanta, GA
*Purpose: Black liver transplant recipients experience poor post-transplant outcomes; little is known about potential mechanisms of this disparity. We investigated whether racial disparities in liver…2020 American Transplant Congress
Cadaveric Uterus Transplant Outcomes: Cleveland Experience
*Purpose: Uterus transplantation (UTx) is a novel treatment modality for women with absolute uterine factor infertility. The majority of uterine transplants performed in the world…2020 American Transplant Congress
Donor Kidney Perfusion Fluid Extracellular Vesicles as Markers of Graft Function
Research Institute of the McGill University Health Institute, Montreal, QC, Canada
*Purpose: Kidney transplantation is a life-saving treatment for many patients with end-stage renal failure. Recently, machine perfusion of kidneys prior to transplantation has emerged as…2020 American Transplant Congress
CD47/SIRPα Signaling Controls TLR4-Driven Inflammatory Response via Regulating the Akt-β-Catenin Axis in Mesenchymal Stem Cell (MSC)-Mediated Immune Regulation in Liver Ischemia and Reperfusion Injury
Surgery, Dumont - UCLA Transplant Ctr, Los Angeles, CA
*Purpose: Innate immune-driven local inflammation induced by ischemia/reperfusion injury (IRI) causes hepatic dysfunction and failure following liver transplantation. Although mesenchymal stem cell (MSC)-based therapy has…2020 American Transplant Congress
Post-Operative Delirium and Cognitive Decline in Kidney Transplant Recipients
*Purpose: Post-operative delirium may be a marker for greater cognitive vulnerability to stressors. As a result, those with post-operative delirium may experience steeper decline in…2020 American Transplant Congress
Navigating Through IgM Antibodies in Deceased Donor Kidney Transplants from A2/A2B Donors to B Recipients
University of Texas Medical Branch, Galveston, TX
*Purpose: Multiple studies have shown acceptable deceased donor transplant (DDT) outcomes from A2 and A2B donors into B recipients; however, concerns remain for acute rejection…
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