Am J Transplant, Volume 20, Suppl 3 Archives - Page 194 of 223 - ATC Abstracts

2020 American Transplant Congress
From Nudge to Nudges: Organizational Factors Explaining Different Incentives but Similarly Low Kidney Donation Outcomes in Singapore, Hong Kong, and Taiwan
W. Lu
University of Chicago, Chicago, IL
*Purpose: The research asks why global living and deceased donor rates of the past 15 years in advanced economies far exceed those occurring in Singapore,…
2020 American Transplant Congress
Kidney Graft Survival by the Teaching Status of a Transplant Center (2008-2019)
K. Maroney, Z. Wang, K. Ross, J. Hogan, R. Patzer
Emory University, Atlanta, GA
*Purpose: Graft survival is an important metric in which transplant centers are graded, yet center-level variation in kidney graft survival still exist after accounting for…
2020 American Transplant Congress
Enumeration of Platelets by Flow Cytometry Reveals Human Erythrocyte Fragmentation During Pig Organ Xenoperfusion Studies
Z. Abady¹, K. M. Petitpas¹, L. Burdorf¹, S. G. Pratts¹, B. M. Cerel¹, S. Sendil², M. R. Connolly¹, W. Qin³, Y. Kan³, J. Layer³, M. Youd³, W. Westlin³, L. Yang³, R. N. Pierson III¹, A. M. Azimzadeh¹
¹Surgery, Massachusetts General Hospital and Harvard School of Medicine, Boston, MA, ²Surgery, University of Maryland School of Medicine, Baltimore, MD, ³eGenesis, Cambridge, MA
*Purpose: Human or baboon platelet sequestration and activation occurs during pig organ xenograft perfusion, although the mechanism remains poorly understood. To evaluate an apparent “rebound”…
2020 American Transplant Congress
Assessment of Rapid Optimized Flow Cytometric Crossmatch (FCXM) Assay with Luminex Class I Single Antibody Test
J. Yoo¹, S. Lee², J. Jang³, A. Choi², E. Oh¹
¹Department of Laboratory Medicine, Catholic University of Korea, Seoul, Korea, Republic of, ²Department of Laboratory Medicine, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ³Department of Biomedical Science, Graduate School, Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: Flow cytometric crossmatch test (FCXM) is critical to detect donor-specific antibodies (DSA) in transplant patients. Rapid, simple and sensitive FCXM procedure can improve HLA…
2020 American Transplant Congress
Laparoscopic Donor Nephrectomy – Call for a Selective Radical Approach
A. Vijay¹, M. Cooper², J. Verbesey², P. Abrams², S. Yi², S. Ghasemian²
¹Transplant Surgery, University of North Carolina, Chapel Hill, NC, ²Transplant Surgery, Medstar Georgetown Transplant Institute, Washington, DC
*Purpose: Introduction: Retrieval of kidneys in obese donor with excessive peri-renal fat has been reported to be more technically challenging with increased incidence of surgical…
2020 American Transplant Congress
Time-Zero Histology Correlates with Donor Characteristics but Does Not Predict Short-Term Outcomes in Kidney Transplantation
S. Raza, G. Agarwal, D. Anderson, M. Deierhoi, H. Fatima, M. Hanaway, J. Locke, P. MacLennan, B. Orandi, C. Young, R. Mannon, M. Seifert
University of Alabama School of Medicine, Birmingham, AL
*Purpose: Time-zero biopsies provide important information about baseline histology but their clinical utility compared to other non-invasive predictors is unclear. Our center performs universal time-zero…
2020 American Transplant Congress
HLA-DQ Plays an Important Role in Graft Survival in African American Transplant Recipients
L. M. Rebellato¹, W. Irish², D. Leeser², J. Tuttle², C. E. Haisch²
¹Pathology, The Brody School of Medicine at ECU, Greenville, NC, ²Surgery, The Brody School of Medicine at ECU, Greenville, NC
*Purpose: Our kidney transplant (KTx) program serves a medically underserved and racially diverse area of a southern state. The purpose of this study was to…
2020 American Transplant Congress
Cell-Free DNA (cfDNA) is Released by Necroptosis and Promotes Kidney Ischemia Reperfusion Injury
A. C. Dionne
Microbiology and Immunology, Western University, London, ON, Canada
*Purpose: Transplantation is invariably associated with ischemia reperfusion injury (IRI) which causes organ dysfunction. IRI is also directly linked to several forms of programmed cell…
2020 American Transplant Congress
Vesicle-Associated Tweak is Increased During Acute Cellular Rejection and Contributes to Endothelial Inflammation
O. Gidlof, J. Sadrian, M. Grossi, S. Alcevska, J. Lundgren, G. Rådegran, G. Smith
Cardiology, Lund University, Lund, Sweden
*Purpose: Extracellular vesicles (EVs) are released from immune cells upon activation and play direct roles in allograft tolerance and rejection, in part through delivery of…
2020 American Transplant Congress
Oral Administration of Nano-Sized Silicon Particles Regulates Gene Expression Related to Oxidative Stress and Attenuates Rat Renal Ischemia Reperfusion Injury
M. Kawamura¹, R. Imamura¹, Y. Kobayashi², A. Taniguchi¹, S. Nakazawa¹, T. Kato¹, T. Abe¹, H. Kobayashi², N. Nonomura¹
¹Department of Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, ²The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, Japan
*Purpose: Organ ischemia reperfusion injury (IRI) is unavoidable in kidney transplantation and induces reactive oxygen species and causes organ damage. Although the effectiveness of hydrogen…