Am J Transplant, Volume 20, Suppl 3 Archives - Page 193 of 223 - ATC Abstracts

2020 American Transplant Congress
Health-Related Quality of Life after Anonymous Nondirected Living Liver Donation: A Multi-Center, North American Collaboration
M. H. Raza¹, W. E. Jackson², A. Dell³, L. Ding⁴, J. Shapiro³, E. A. Pomfret⁵, Y. Genyk⁶, L. Sher⁶, J. Emamaullee⁶
¹Keck School of Medicine of USC, Los Angeles, CA, ²Gastroenterology, University of Colorado, Aurora, CO, ³Surgery, University of Alberta, Edmonton, AB, Canada, ⁴Preventive Medicine, University of Southern California, Los Angeles, CA, ⁵Surgery, University of Colorado, Aurora, CO, ⁶Surgery, University of Southern California, Los Angeles, CA
*Purpose: Literature on anonymous or ‘altruistic’ nondirected living liver donors (ND-LLDs) remains sparse as living donor liver transplant (LDLT) programs continue to explore the utilization…
2020 American Transplant Congress
Use of Letermovir for Cytomegalovirus Management in Thoracic Organ Transplantation
J. L. Saullo, A. Ferrari, E. M. Eichenberger, J. M. Steinbrink, A. W. Baker, M. Bacchus, E. K. Maziarz, S. Kakoullis, L. Zaffiri, H. Berry, J. M. Reynolds, C. R. Wolfe
Duke University Medical Center, Durham, NC
*Purpose: Cytomegalovirus (CMV) commonly affects thoracic solid organ transplant (SOT) recipients, and standard antiviral therapies are limited by myelosuppression, renal dysfunction, and emergence of resistance.…
2020 American Transplant Congress
Proposed New Pancreas Allocation Policy: Moving to Concentric Circles as First Unit of Allocation
A. Israni¹, S. Gustafson¹, B. Thompson¹, A. Wey¹, S. Niederhaus², R. Forbes³, A. Fox⁴, B. Kasiske¹, J. Snyder¹
¹SRTR, Minneapolis, MN, ²Univ of Maryland, Baltimore, MD, ³Vanderbilt Univ, Nashville, TN, ⁴UNOS, Richmond, VA
*Purpose: The Organ Procurement and Transplantation Network (OPTN) proposed a new national deceased donor pancreas allocation policy that removes donor service area and OPTN region…
2020 American Transplant Congress
Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation
H. Hirao¹, T. Ito¹, K. Nakamura², S. Kageyama¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, R. W. Busuttil¹, F. M. Kaldas¹, J. W. Kupiec‐Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
2020 American Transplant Congress
Pancreatic Mesenchymal Stromal Cells (MSC) Contain a Subset of Islet Progenitor Cells Capable of Regenerating Islets and Reversing Diabetes
C. M. Darden¹, S. Vasu², K. Kumano¹, Y. Liu², P. Saravanan³, B. Naziruddin², M. Lawrence²
¹Institute of Biomedical Studies, Waco, TX, ²Baylor University Medical Ctr, Dallas, TX, ³Transplant Surgery Department, VCU, Richmond, VA
*Purpose: To identity islet precursor cells residing in pancreatic MSC culture preparations that contribute to islet regeneration and restoration of islet cell function in both…
2020 American Transplant Congress
Early Experience Transplanting Undocumented Immigrants with ESRD at a Single Institution: Outcomes and Challenges
R. T. Christie¹, R. M. Nygaard², C. J. Richardson¹, M. J. Hill¹, T. Anderson-Haag³, A. Israni⁴, P. A. Stahler¹
¹Transplant Surgery, Hennepin Healthcare, Minneapolis, MN, ²Surgery, Hennepin Healthcare, Minneapolis, MN, ³Transplant Pharmacy, Hennepin Healthcare, Minneapolis, MN, ⁴Nephrology, Hennepin Healthcare, Minneapolis, MN
*Purpose: In July of 2016, Minnesota became the second state in the nation to provide coverage for kidney transplantation to patients, regardless of immigration status,…
2020 American Transplant Congress
Fate of Donor-Derived Regulatory Dendritic Cells (DCreg) and Augmentation of Host Regulatory T Cells Following Their Infusion Into Prospective Living-Donor Liver Transplant Recipients
A. W. Thomson, C. Macedo, A. F. Zahorchak, X. Gu, A. Humar, F. G. Lakkis, M. A. Styn, D. M. Metes
Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Our purpose was to ascertain the fate of ex vivo-generated donor-derived DCreg and their influence on host T cells prior to transplant in a…
2020 American Transplant Congress
The Liver Outcome Monitoring Registry Donor Risk Index: A New Measure of Deceased Donor Liver Quality
S. Kurian¹, J. Case¹, A. Robinson², B. Barrick¹, M. Prentice², C. Marsh¹
¹Scripps Center for Organ and Cell Transplantation, La Jolla, CA, ²United Network for Organ Sharing Research Department, Richmond, VA
*Purpose: The liver donor risk index (LDRI) created in 2006 evaluated the relative risk of graft failure, however its weaknesses have limited its use in…
2020 American Transplant Congress
Pathogenesis of Polyomavirus BK Nephropathy (BKVN): Insights from Quantitative Proteomics Profiling
P. Randhawa¹, F. Fei², Y. Huang³, G. Tseng⁴, K. Xiao⁵
¹UPMC-Montefiore Hospital, Pittsburgh, PA, ²Pharmacology and Chemical Biology,, University of Pittsburgh, Pittsburgh, PA, ³Univeristy of Pittsburgh, Pittsburgh, PA, ⁴Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ⁵Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Our current understanding of the pathogenesis of BKVN is based primarily on transcriptomics studies. However, proteins are the final effector molecules that mediate tissue…
2020 American Transplant Congress
Survey on Solid Organ Pancreas Transplantation in the United States: Plenty of Insulin, Short on Procedures!
R. F. Parsons¹, T. Alhamad², K. L. Lentine³, A. Basu¹, K. J. Woodside⁴, G. Romeo⁵, C. Klein⁶, M. Pavlakis⁷, J. Friedewald⁸, D. Dadhania⁹, M. Cooper¹⁰
¹Emory Univ, Atlanta, GA, ²Washington Univ, St. Louis, MO, ³St. Louis Univ, St. Louis, MO, ⁴Univ Michigan, Ann Arbor, MI, ⁵Harvard, Boston, MA, ⁶Piedmont, Atlanta, GA, ⁷BIDMC, Boston, MA, ⁸Northwestern, Chicago, IL, ⁹Weill Cornell Medical College – NYP, New York, NY, ¹⁰Georgetown Univ, Washington, DC
*Purpose: For 15 years pancreas transplantation (PT) numbers have paradoxically declined. We sought to understand the drop in all types of PT and to find…