Am J Transplant, Volume 20, Suppl 3 Archives - Page 182 of 223 - ATC Abstracts

2020 American Transplant Congress
Patient-Reported Outcomes in a Prospective Multicenter Trial of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression Regimens in Kidney Transplantation: A Prospective Analysis Across Two Years
J. M. Rohan¹, J. Leone², E. Woodle³, D. Kaufman⁴, A. Shields⁵, A. Wiseman⁶, A. Matas⁷, P. West-Thielke⁸, E. King⁵, R. Alloway³
¹Pediatrics, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, ²Tampa General, Tampa, FL, ³University of Cincinnati, Cincinnati, OH, ⁴U Wisconsin, Madison, WI, ⁵U Cincinnati, Cincinnati, OH, ⁶U Colorado, Denver, CO, ⁷U Minnesota, Minneapolis, MN, ⁸UIC, Chicago, IL
*Purpose: Previous trials have not examined 2-year longitudinal differences in patient-reported outcomes (PRO) between belatacept (BELA)- and tacrolimus (TAC)-based therapies in adult kidney transplant (KTx)…
2020 American Transplant Congress
Broader Distribution of Kidneys Not Projected to Systematically Favor “Low” Performing OPOs
A. Wilk¹, S. Gustafson², D. Stewart¹, N. Salkowski², D. Zaun², J. Snyder²
¹UNOS, Richmond, VA, ²Hennepin Healthcare Research Institute, Minneapolis, MN
*Purpose: In August 2019, the OPTN Kidney (KI) Transplantation Committee put forth a proposal for public comment to replace DSA and region from KI allocation…
2020 American Transplant Congress
Development of a New Kidney Paired Donation (KPD) Program: Starting a Domino Chain with a Deceased Donor
L. Furian¹, C. Di Bella², C. Silvestre², F. Neri², F. Tuci², M. Cardillo³, E. Cozzi⁴, P. Rigotti¹
¹Kidney and Pancreas Transplantation Unit, University of Padova, Padua, Italy, ²Kidney and Pancreas Transplantation Unit, University of Padova, Italy, Italy, ³Italian National Transplant Center, Rome, Rome, Italy, ⁴Transplant Immunology Unit, Padova University-Hospital, Padua, Padua, Italy
*Purpose: The option of initiating a domino chain of living donor kidney transplants with a deceased donor (DD) has been proposed but never enforced. The…
2020 American Transplant Congress
A Multi-Center Pilot and Feasibility Randomized Clinical Trial of a Home-Based Exercise Program for Patients with Cirrhosis: The Strength Training Intervention
J. C. Lai¹, M. R. Kappus², J. L. Dodge¹, R. Wong¹, Y. Mohamad¹, D. L. Segev³, M. A. McAdams-DeMarco⁴
¹University of California, San Francisco, San Francisco, CA, ²Duke University, San Francisco, NC, ³Johns Hopkins Medical Institute, Baltimore, MD, ⁴Johns Hopkins School of Public Health, Baltimore, MD
*Purpose: Patients with cirrhosis experience progressive physical frailty and functional decline that may ultimately lead to an increased risk of death. We developed the Strength…
2020 American Transplant Congress
Impact of Donor Multidrug-Resistant Organisms on Risk of Recipient Infection
J. A. Anesi¹, E. A. Blumberg¹, J. H. Han², D. H. Lee³, H. Clauss⁴, R. Hasz⁵, E. Molnar⁴, D. Alimenti¹, A. R. Motzer⁴, S. West⁵, W. B. Bilker¹, P. Tolomeo¹, E. Lautenbach¹, T. Prevention Epicenters Program⁶
¹University of Pennsylvania, Philadelphia, PA, ²GlaxoSmithKline, Rockville, MD, ³Drexel University, Philadelphia, PA, ⁴Temple University, Philadelphia, PA, ⁵Gift of Life Donor Program, Philadelphia, PA, ⁶Centers for Disease Control and Prevention, Atlanta, GA
*Purpose: Although there is concern about the use of donor organs that are infected or colonized with multidrug-resistant organisms (MDROs), their impact on solid organ…
2020 American Transplant Congress
High-Risk Antibodies Pre-Transplant Impacts Outcome after Heart Transplantation
J. A. Kobashigawa, M. Kittleson, J. Patel, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, A. Shen, L. Czer, F. Esmailian
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Pre-transplant circulating antibodies (Abs) are known to impact outcome after heart transplantation (HTx). Abs can now be detected by single-bead assay but also characterized…
2020 American Transplant Congress
Transient Cd4+ T Cell and Cd20+ B Cell Depletion Leads to Prolonged Pig-To-Primate Kidney Xenograft Survival
B. P. Lovasik¹, A. J. Matar¹, D. A. Faber¹, D. V. Mathews¹, C. Breeden¹, S. C. Kim¹, A. J. Tector², A. B. Adams¹
¹Emory University School of Medicine, Atlanta, GA, ²University of Miami, Miami, FL
*Purpose: “Delayed” antibody-mediated xenograft rejection is the one of the most important obstacle to clinical application of pig organ xenografts. The aim of this study…
2020 American Transplant Congress
Prospective, Randomized Study of Conversion from Calcineurin Inhibitor (CNI)- to Belatacept (BELA)-Based Maintenance Immunosuppression in Renal Transplant Recipients
K. Budde¹, R. Prashar², H. Haller³, M. Rial⁴, N. Kamar⁵, A. Agarwal⁶, J. de Fijter⁷, L. Rostaing⁸, S. Berger⁹, A. Djamali¹⁰, N. Leca¹¹, L. Allamassey¹², S. Gao¹², M. Polinsky¹², F. Vincenti¹³
¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Henry Ford Hospital, Detroit, MI, ³The Hannover Medical School, Hannover, Germany, ⁴Instituto de Nefrologia, Nephrology SA, Buenos Aires, Argentina, ⁵University of Toulouse, Toulouse, France, ⁶UVA Health, Charlottesville, VA, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Université Grenoble Alpes, Saint-Martin-d'Hères, France, ⁹University Medical Centre Groningen, Groningen, Netherlands, ¹⁰University of Wisconsin, Madison, WI, ¹¹UW Medical Center, Seattle, WA, ¹²Bristol-Myers Squibb, Princeton, NJ, ¹³University of California, San Francisco, San Francisco, CA
*Purpose: CNIs are associated with adverse systemic and nephrotoxic effects that negatively impact long-term patient and graft survival. In a phase 2 study, switching renal…
2020 American Transplant Congress
Parathyroidectomy Post Kidney Transplant: A Single Center Report of Short Term Outcomes
S. Ong, F. Saad, K. Wille, C. Kew
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Whether parathyroidectomy in ESRD patients should be performed before or after kidney transplant remains controversial. There is concern that post-transplant parathyroidectomy can adversely affect…
2020 American Transplant Congress
Transarterial Chemoembolization and Radio-Embolization are Similarly Efficacious in Achieving Successful Hepatocellular Carcinoma (HCC) Down-Staging: Results from the Multicenter Evaluation of Reduction in Tumor Size Before Liver Transplantation (MERITS-LT) Consortium
N. Mehta¹, J. Guy², C. Frenette³, P. Tabrizian⁴, M. Hoteit⁵, N. Parikh⁶, T. Ghaziani⁷, R. Dhanasekaran⁷, J. L. Dodge¹, M. L. Holzner⁴, S. Florman⁴, F. Yao¹
¹UCSF, SF, CA, ²CPMC, SF, CA, ³Scripps Hospital, La Jolla, CA, ⁴Mt Sinai, NY, NY, ⁵U. Pennsylvania, Philadelphia, PA, ⁶U. Michigan, Ann Arbor, MI, ⁷Stanford, Palo Alto, CA
*Purpose: United Network of Organ Sharing (UNOS) Region 5 has reported excellent liver transplantation (LT) outcomes after successful down-staging (DS) in HCC patients exceeding Milan…