Am J Transplant, Volume 20, Suppl 3 Archives - Page 167 of 223 - ATC Abstracts

2020 American Transplant Congress
Attempted Validation of Lims1 Variant Rs893403 with Acute Rejection Risk
W. S. Oetting¹, G. Weihua¹, C. R. Dorr¹, R. B. Mannon², A. J. Matas¹, P. A. Jacobson¹, A. K. Israni¹
¹University of Minnesota, Minneapolis, MN, ²University of Alabama, Birmingham, AL
*Purpose: Acute rejection (AR) in kidney allograft recipients is a significant risk factor for reduced graft survival. Identifying individuals at risk for AR could facilitate…
2020 American Transplant Congress
Ex Vivo Normothermic Perfusion Improves Cold Ischemic Injury and DGF in an Experimental Model of DBD Kidney Transplantation
A. Gutierrez-Dalmau¹, V. Alastrue², Á. García De Jalon³, M. Sánchez³, C. Del Agua⁴, V. P. González⁵, Á. Roncales³, J. Gómez-Arrue⁶, C. Pastor⁶, B. Sáez⁷, L. M. Esteban⁸, M. J. Gil³, M. Doblaré⁹, Á. Borque-Fernando³
¹Nephrology, Hospital Universitario Miguel Servet (HUMS), IIS Aragón, Zaragoza, Spain, ²EBERS, Zaragoza, Spain, ³Urology, HUMS, Zaragoza, Spain, ⁴Pathology, HUMS, Zaragoza, Spain, ⁵Hematology, HUMS, Zaragoza, Spain, ⁶Experimental Surgery, IACS, Zaragoza, Spain, ⁷Faculty of Health Sciences, San Jorge University, Zaragoza, Spain, ⁸EUPLA, Zaragoza University, Zaragoza, Spain, ⁹Department of Mechanical Engineering, Zaragoza University, Zaragoza, Spain
*Purpose: Cold ischemic (CI) injury results in high rates of DGF, reduced graft function and survival. Ex vivo normothermic perfusion (EVNP) has shown to improve…
2020 American Transplant Congress
Intra-Lymph Node Injection of Rapamycin-Alloantigen Microparticles Regulates Dendritic Cell Antigen Presentation
C. M. Paluskievicz¹, Y. Xiong¹, W. Piao¹, M. Willson-Shirkey¹, H. Eppler², C. M. Jewell², J. S. Bromberg¹
¹U Maryland, Baltimore, MD, ²U Maryland, College Park, MD
*Purpose: Microparticles (MPs) carrying peptide antigen with immune signals can be directly delivered to lymph nodes (LNs) via intra-LN injections to shape both pro-inflammatory or…
2020 American Transplant Congress
Robot-Assisted versus Open Kidney Transplantation for Morbidly Obese Patients
S. D. Lee¹, B. Rawashdeh², E. K. McCracken², L. A. Cantrell³, A. Demirag², A. Agarwal², K. L. Brayman², S. J. Pelletier², J. Oberholzer²
¹Surgery, VCU Health, Richmond, VA, ²Surgery, University of Virginia, Charlottesville, VA, ³Obstetrics and Gynecology, University of Virginia, Charlottesville, VA
*Purpose: Obesity significantly impacts intraoperative and postoperative complications following kidney transplantation. Consequently, many centers deny access to transplantation in patients with a body mass index…
2020 American Transplant Congress
Anti-T Lymphocyte Immunoglobulins versus Basiliximab in Highly Sensitized Kidney-Transplant Patients without Preformed DSAs: The Satir Study
N. Kamar¹, L. Couzi², L. Albano³, A. Durrbach⁴, V. Pernin⁵, L. Esposito¹, M. Lequintrec⁵, P. Merville², A. Del Bello¹
¹Toulouse University Hospital, Toulouse, France, ²Bordeaux University Hospital, Bordeaux, France, ³Nice University Hospital, Nice, France, ⁴Henri Mondor University Hospital, Paris, France, ⁵Montpellier University Hospital, Montpellier, France
*Purpose: Two prospective studies that were performed before the era of highly sensitive solid-phase assays have shown a lower incidence of acute rejection in highly…
2020 American Transplant Congress
Double or Nothing: Reducing Organ Discards by Preemptive Dualization of ‘at Risk’ Single Kidney Offers
S. K. Patel¹, S. Chang², R. Plews¹, R. Sussman³, D. Disante³, D. Schuster¹, P. Nguyen¹, R. Lopez-Soler⁴, D. Conti¹
¹Kidney Pancreas Transplant Division, Albany Medical Center, Albany, NY, ²Nephrology, University at Buffalo, Buffalo, NY, ³CDT, Albany Medical Center, Albany, NY, ⁴Renal Transplant Program, Edward Hines Jr., VA Medical Center, Chicago, IL
*Purpose: The purpose of this study is to evaluate a protocol designed to (1) enhance early identification of “at risk” single kidney offers (SKO) and…
2020 American Transplant Congress
Serum Osteopontin Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Kidney Transplant Patients
B. Hsu¹, Y. Lai¹, M. Lee²
¹Division of Nephrology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, ²Department of Surgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
*Purpose: Osteopontin (OPN) is a potent inhibitor of mineralization and is a potent inducible inhibitor of vascular calcification. Studies in patients noted elevated levels of…
2020 American Transplant Congress
Facebunk: Does Social Media Have a Positive Impact on Living Kidney Donation
E. K. Venniro¹, R. Kashyap², J. G. Taylor¹
¹Nephrology, University of Rochester Medical Center, Rochester, NY, ²Surgery, University of Rochester Medical Center, Rochester, NY
*Purpose: More kidney transplant recipients are reaching out beyond their immediate contacts in order to find potential living donors. In addition, transplant centers and organizations…
2020 American Transplant Congress
Effect of Cold Ischemia Time on Long-Term Graft Survival of Post-One Year Survivor Deceased Donor Kidney Transplant Recipients
B. Murthy¹, H. Nguyen², A. Rana¹, A. Awan¹, C. Van Buren³, J. Goss¹
¹Baylor College of Medicine, Houston, TX, ²University of Texas Medical Branch, Galveston, TX, ³University of Texas Houston Medical School, Houston, TX
*Purpose: Prolonged cold ischemia time (CIT) is known to adversely affect short-term graft survival among renal allografts. However, its effect on long-term graft survival is…
2020 American Transplant Congress
Can HLA-DQ Molecular Mismatch Analysis Be Used to Predict Generation of De Novo Donor-Specific Antibody at an Individual Patient Level?
D. Pinelli¹, M. Casillas Abundis¹, R. Hod Dvorai², H. McDowell¹, A. R. Tambur¹
¹Northwestern University, Chicago, IL, ²SUNY Upstate Medical University, Syracuse, NY
*Purpose: De novo donor-specific antibodies (dnDSA), especially to HLA-DQ, are one of the leading causes of late kidney graft failure. Many investigators have attempted to…