Am J Transplant, Volume 20, Suppl 3 Archives - Page 164 of 223 - ATC Abstracts

2020 American Transplant Congress
Acute Liver Failure Etiology is an Independent Predictor of Waitlist Outcome Accounting for Severity of Illness in a National Cohort
N. Z. Wong, K. R. Reddy, T. Bittermann
University of Pennsylvania, Philadelphia, PA
*Purpose: Severity of illness and liver transplant (LT) waitlist outcome can differ according to acute liver failure (ALF) etiology. However, it is unknown whether ALF…
2020 American Transplant Congress
Pharmacokinetics of Maribavir in Subjects with Moderate Hepatic Impairment
I. H. Song¹, K. Ilic², J. Wu³
¹Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, ²Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, ³Biostat, Shire, a Takeda Company, Lexington, MA
*Purpose: Maribavir, an investigational agent for cytomegalovirus (CMV) infection in transplant recipients, has received Breakthrough Therapy Designation. Maribavir is metabolized primarily in the liver through…
2020 American Transplant Congress
Impact and Outcomes of Primary Cytomegalovirus Infection in Seronegative Abdominal Solid Organ Transplant Recipients of Cytomegalovirus Unexposed Donors (D-/R-)
M. Jorgenson¹, M. Hillis¹, N. Friedlander¹, A. Gracon², D. Yang², G. Leverson², J. Smith², R. Redfield²
¹UWHC, Madison, WI, ²UWMF, Madison, WI
*Purpose: Primary cytomegalovirus infection (CMV) in high risk (D+/R-) abdominal solid organ transplant recipients (aSOTRs) is well described, however there is a paucity of literature…
2020 American Transplant Congress
Long-Term Safety in Epstein-Barr Virus (EBV)-Seropositive Kidney-Only Transplant Recipients Treated with Belatacept (BELA) in Clinical Practice: Final Study Results from the ENLiST Registry
C. Larsen¹, F. Vincenti², T. Kou³, C. Shadur⁴, B. Bresnahan⁵, S. Jordan⁶, E. S. Woodle⁷, N. Goes⁸, J. Vella⁹, D. Wojciechowski¹⁰, M. Polinsky³, A. Gomez-Caminero³
¹Emory University Transplant Center, Atlanta, GA, ²UCSF Transplant Center, San Francisco, CA, ³Bristol-Myers Squibb, Princeton, NJ, ⁴Iowa Kidney Physicians, Des Moines, IA, ⁵Medical College of Wisconsin, Milwaukee, WI, ⁶Cedars-Sinai Medical Center, Los Angeles, CA, ⁷University of Cincinnati, Cincinnati, OH, ⁸Kaiser Permanente, San Francisco, CA, ⁹Maine Nephrology Associates, PA, Portland, ME, ¹⁰University Hospital Kidney and Liver Transplant Clinic, Dallas, TX
*Purpose: BELA, a selective T-cell costimulation blocker, is approved for the prophylaxis of organ rejection in EBV-seropositive adult kidney transplant recipients. In phase 3 BENEFIT…
2020 American Transplant Congress
The Role and Impact of Transplant Pharmacist Evaluation in a Pre-Kidney Transplant Clinic
B. Valdepenas, D. Choi, J. Benken, M. Campara
Pharmacy Practice and Transplant Surgery, University of Illinois at Chicago, Chicago, IL
*Purpose: The Centers for Medicare and Medicaid Services’ interpretative guidelines for conditions of participation for transplant centers define the transplant pharmacist’s role ambiguously. Limited evidence…
2020 American Transplant Congress
Geographical Disparities in Transplantation: Exploring the Association between County Health Rankings and an Individual’s Access to Transplantation
A. J. Carter, R. D. Reed, D. Hendricks, K. N. Baldwin, A. C. Kale, J. E. Locke
Surgery, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Since 2004, living kidney donation has declined, with the southeastern United States disproportionately affected. Programs such as the Living Donor Navigator (LDN), designed to…
2020 American Transplant Congress
Estimating the Potential Pool of Uncontrolled DCD Donors in the United States
B. J. Boyarsky, K. R. Jackson, A. B. Kernodle, J. V. Sakran, J. M. Garonzik Wang, S. E. Ottmann, D. L. Segev
Johns Hopkins, Baltimore, MD
*Purpose: In contrast to donation after brain death (DBD), donation after circulatory death (DCD) involves recovery of organs from people with devastating neurologic injury who…
2020 American Transplant Congress
Impact of Worsening Renal Function While Waiting for Heart Transplantation
A. Kumar¹, C. P. Thomas²
¹Internal Medicine, University of Vermont, Burlington, VT, ²Internal Medicine, University of Iowa, Iowa City, IA
*Purpose: Pre transplant renal function has been shown to be a strong predictor of long term renal as well as patient survival in heart transplant…
2020 American Transplant Congress
Improved Kidney Function Post Lung Transplant with Intravenous Tacrolimus Avoidance
C. Burt¹, A. Feist¹, K. Afshar², L. Awdishu¹, M. Mariski¹, J. Kozuch¹, G. Yung², E. Golts³
¹Pharmacy, UC San Diego Health, San Diego, CA, ²Pulmonology, UC San Diego Health, San Diego, CA, ³Cardiothoracic Surgery, UC San Diego Health, San Diego, CA
*Purpose: Tacrolimus (TAC) poses a dose-dependent risk of acute kidney injury (AKI) as well as chronic kidney disease (CKD) post-transplant. In 2017, our institution’s lung…
2020 American Transplant Congress
Single Center Snapshot Experience of dd-cfDNA in Lung Transplantation
D. Levine, P. Ong, D. De Armond, E. Sako
University of Texas Health San Antonio, San Antonio, TX
*Purpose: Chronic lung allograft dysfunction (CLAD) is the primary etiology of graft failure and associated with poor survival post lung transplantation (LT). Risk factors for…