ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Kidney after Intestinal Transplantation: A Comparison with Combined Kidney with Intestinal Transplant. A UNOS Database Analysis

    A. Sharfuddin, M. Panezai, O. Adebiyi, T. Taber, M. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: There is limited data on outcomes for patients receiving a isolated kidney transplant (KAIT) after any prior Multi-organ or Isolated Intestinal transplant (IT). We…
  • 2020 American Transplant Congress

    Immunomodulation with FasL Presenting Biomaterials Achieves Long-Term Survival of Allogeneic Islets in the Absence of Chronic Immunosuppression in a Non-Human Primate Model

    J. Lei1, H. Deng1, T. Chen1, K. Lee1, C. Peters1, Z. Yang1, K. Deng1, G. Rickert1, I. Rosales1, N. Serifis1, M. Coronel2, M. Hunckler2, E. Yolcu3, H. Shirwan3, A. García2, J. Markmann1

    1Surgery, Mass General, Boston, MA, 2School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, 3School of Mechanical Engineering, University of Louisville School of Medicine, Louisville, KY

    *Purpose: The full potential of islet transplantation will only be realized by the development of tolerogenic strategies that obviate the need for maintenance immunosuppressants. We…
  • 2020 American Transplant Congress

    Outcomes Associated with Mycophenolate Weight-Based Dosing in Varying Immunologic Risk Kidney Transplant Recipients

    A. A. Al-Bahou, A. R. Webb, M. Bloxam, L. J. Bowman Anger, R. S. Baliga, A. J. Brueckner

    Tampa General Hospital, Tampa, FL

    *Purpose: Mycophenolate acid (MPA) is traditionally dosed in kidney transplant recipients (KTR) using the FDA-approved fixed dosing which is irrespective of patient-specific variables such as…
  • 2020 American Transplant Congress

    CHAIR Score: A Novel Risk Stratification in Transplant Renal Artery Stenosis

    X. Tian, W. Duan, T. Yan, X. Wu

    Henan Province People's Hospital, Zhengzhou, Henan Province, China

    *Purpose: The aim of the study is to evaluate the clinical application of CHAIR score based on creatinine (C), hypertension (H), age (A), imaging evidence…
  • 2020 American Transplant Congress

    The Impact of Cold Ischaemia Time on Living Donor Kidney Transplantation Outcomes

    S. C. van de Laar1, M. Robb2, R. Hogg2, V. Papalois1, F. J. Dor1

    1Department of Surgery & Cancer, Imperial College London, Imperial College Renal and Transplant Centre, Hammersmith Hospital, Imperial College Healthcare NHS Trust, White City, London, United Kingdom, 2NHS Blood and Transplant, Bristol, United Kingdom

    *Purpose: Living donor KTx (LDKT) provides the best option for patients with end-stage kidney disease (ESKD). ESKD patients who have an incompatible living donor still…
  • 2020 American Transplant Congress

    Sequential Protocol Biopsies Post-Liver Transplant from Donors with Moderate Macrosteatosis: What Happens to the Fat?

    K. Croome, D. Livingston, C. Taner, R. Nakhleh

    Mayo Clinic Jacksonville, Jacksonville, FL

    *Purpose: The number of steatotic deceased donor livers encountered has continued to rise as a result of the obesity epidemic. Little is known about the…
  • 2020 American Transplant Congress

    Anticipated Cost Savings of Using Lungs from Hepatitis C-Positive Lung Donors for Hepatitis C-Negative Recipients

    K. Ryland1, J. Mallea2, J. Moriarty3, L. White4, B. Borah5, J. Naessens3

    1Transplantation, Mayo Clinic, Jacksonville, FL, 2Medicine, Mayo Clinic, Jacksonville, FL, 3Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, 4Health Sciences Research, Mayo Clinic, Jacksonville, FL, 5Health Sciences Research, Mayo Clinic, Rochester, MN

    *Purpose: We assessed the cost savings generated by additional organ availability due to utilizing lungs from hepatitis-C infected donors for transplantation in comparison to existing…
  • 2020 American Transplant Congress

    TIM-4+ Kupffer Cells Play Homeostatic Roles in Liver Ischemia Reperfusion Injury

    M. Ni1, J. Zhang1, R. Sosa2, S. Kageyama1, R. Busuttil1, R. Elaine2, J. Kupiec-Weglinski1, X. Wang3, Y. Zhai1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2Pathology, David Geffen School of Medicine-UCLA, Los Angeles, CA, 3Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: Liver ischemia reperfusion injury (IRI) remains a significant clinical problem. Although the molecular mechanism of liver inflammatory response against IR has been studied extensively,…
  • 2020 American Transplant Congress

    T Cell Activation by Allogeneic EVs and Allogeneic MHC Cross-Dressed Cells In Vitro and In Vivo

    A. Prunevieille1, B. Gonzalez-Nolasco1, G. Benichou1, N. Mooney2, A. Colleen3

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2INSERM, Paris, France, 3Boston College, Boston, MA

    *Purpose: The recognition of donor-MHC molecules by recipient T cells triggers the immune response leading to rejection of allografts. Our recent studies have documented the…
  • 2020 American Transplant Congress

    Consequences of Turning Down High KDPI Kidney Organ Offers for Kidney Transplant Candidates

    J. D. Motter, L. Liyanage, K. R. Jackson, M. G. Bowring, T. Ishaque, Y. Yu, S. Yu, J. M. Garonzik-Wang, A. B. Massie, D. L. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Kidneys with a high Kidney Donor Profile Index (KDPI, 80-100%) are frequently declined as they are associated with higher graft loss; yet, candidates that…
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