2020 American Transplant Congress
Factors Associated with Hepatocellular Carcinoma Understaging for Liver Transplantation, and Variation in Understaging by Transplant Center
1Hospital of the University of Pennsylvania, Philadelphia, PA, 2University of Miami, Miami, FL
*Purpose: Hepatocellular carcinoma (HCC) may be cured by liver transplantation (LT) in selected patients, though recurrence rates remain high. Patients who are reported as within…2020 American Transplant Congress
Financial Feasibility of a Culturally Competent and Linguistically Congruent Hispanic Kidney Transplant Program
1Northwestern U Feinberg Sch of Medicine, Chicago, IL, 2University of Arizona, Tuscon, AZ
*Purpose: Relative to their representation on the waitlist, Hispanics/Latinos received significantly fewer LDKTs than non-Hispanic Whites in 2018: 5.0% versus 12.2%. In 2006, Northwestern Medicine…2020 American Transplant Congress
Outcomes and Health Care Utilization after Early Hospital Dismissal in Kidney Transplantation: An Analysis of 1001 Consecutive Cases
*Purpose: Perioperative care after kidney transplantation has improved with reduction in length of operative stay to as low as two days, but this has an…2020 American Transplant Congress
Identification of Novel Gene Targets Inducing Resistance in Liver Ischemia Reperfusion Injury by CRISPR Screening
*Purpose: Liver transplantation (LT) is the best treatment option for patients with end-stage liver disease (ESLD). However, the gap between available donors and recipients in…2020 American Transplant Congress
Autophagy-Lysosome Inhibitor Chloroquine Prevents CTLA-4 Degradation of T Cells and Attenuates Acute Rejection in Murine Skin and Heart Transplantation
*Purpose: The immune checkpoint cytotoxic T lymphocyte antigen-4 (CTLA-4), which was induced upon T cell activation but degraded quickly, has been targeted in the clinical…2020 American Transplant Congress
Steroid Withdrawal and Lymphocyte Subsets in Graft Capillary Blood versus Peripheral Blood in Low Immunological Risk Kidney Transplant Patients: Randomized, Parallel Group, Controlled Clinical Trial
Regional University Hospital, Malaga, Spain
*Purpose: Whether steroid withdrawal can modulate the subclinical inflammatory response after a kidney transplant is unknown.*Methods: We undertook a controlled multicenter clinical trial involving 105…2020 American Transplant Congress
Three-Month Results of a Phase 2 Trial Evaluating Clazakizumab in Late Antibody-Mediated Rejection – Early Impact of Interleukin-6 Blockade on Donor-Specific Antibody Levels, Rejection Morphology and Gene Expression
*Purpose: Targeting Interleukin-6 (IL-6) is a promising strategy to counteract antibody-mediated rejection (ABMR). This phase 2 trial (NCT03444103) was designed to evaluate the safety and…2020 American Transplant Congress
Does Choice of Inferior Vena Cava Reconstruction Technique Have an Impact on the Short and Long Term Postoperative Renal Function in Liver Transplant Recipient?
1Vancouver General Hospital, Vancouver, BC, Canada, 2Baylor University Medical Center, Dallas, TX
*Purpose: Postoperative acute kidney injury (AKI) is common after liver transplant (Oltx). It is associated with increased morbidity and mortality and is a risk factor…2020 American Transplant Congress
Impact of Frailty on Early and Late Hospital Readmission after Kidney Transplantation
*Purpose: Currently there are no tools to predict outcomes after kidney transplantation (KTx). This study assesses whether frailty influences post-KTx complications. Understanding frailty and its…2020 American Transplant Congress
Effect of DSA-Free Heart Allocation
1University of Michigan, Ann Arbor, MI, 2SRTR, Minneapolis, MN, 3UT Southwestern, Dallas, TX
*Purpose: Currently, donation service area (DSA) is the first geographic unit for heart allocation, which creates discrepancies in access for high-urgency candidates. We studied the…
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