Am J Transplant, Volume 20, Suppl 3 Archives - Page 149 of 223 - ATC Abstracts

2020 American Transplant Congress
Cyclophilin-D Inhibition Mitigates Cardiac Allograft Ischemia-Reperfusion Injury and Rejection
A. Qamar¹, P. McLeod², J. Jiang², X. Huang², A. M. Jevnikar², Z. Zhang²
¹Pathology & Laboratory Medicine, University of Western Ontario, London, ON, Canada, ²London Health Sciences Center, London, ON, Canada
*Purpose: The clinical relevance of ischemia-reperfusion injury (IRI) in the context of organ transplantation is well-established. IRI is associated with various forms of programmed cell…
2020 American Transplant Congress
Contamination of Acinar Cells Impairs Therapeutic Effect of Islet Transplantation Due to Induction of Inflammatory Reaction in Not Only Graft Islets but Also Hepatic Parenchyma
K. Chinen, G. Yoshimatsu, N. Sakata, S. Kodama
Regenerative Medicine and Transplantation, Fukuoka University, Fukuoka City, Japan
*Purpose: Islet transplantation is a promising treatment option for type 1 diabetes. Edmonton protocol recommended that over 30 % purity of islets is essential for…
2020 American Transplant Congress
Intra-Lymph Node Injection of Microparticles Reprograms the Laminin Stromal Network to Prolong Allograft Survival
C. M. Paluskievicz¹, Y. Xiong¹, W. Piao¹, M. Willson-Shirkey¹, H. Eppler², C. M. Jewell², J. S. Bromberg¹
¹U Maryland, Baltimore, MD, Baltimore, MD, ²U Maryland, College Park, MD, College Park, MD
*Purpose: Microparticles (MPs) carrying peptide antigen with immune signals can be directly delivered to lymph nodes (LNs) to induce pro-inflammatory or anti-inflammatory responses. We hypothesized…
2020 American Transplant Congress
Safety and Efficacy of Low Dose Rabbit Antithymocyte Globulin in Pediatric Renal Transplant Recipients
V. K. Sigurjonsdottir¹, L. Maestretti¹, A. McGrath¹, A. Gallo², W. Concepcion², P. Grimm¹, A. Chaudhuri¹
¹Pediatric Nephrology, Stanford University, Stanford, CA, ²Surgery - Multi-Organ Transplantation, Stanford University, Stanford, CA
*Purpose: Currently there is no consensus among pediatric kidney transplant centers regarding the use and regimen for immunosuppressive induction therapy.The safety and effectiveness of reduced…
2020 American Transplant Congress
The Time is Now: Improving Waiting Times in Minority Populations
L. Mendez-Castaner, L. Preczewski, M. Muldoon, A. Harshman, M. Goble, G. Guerra
Miami Transplant Institute, Miami, FL
*Purpose: A significant limiting factor to transplantation resides on waiting time based on blood type. Historically candidates in blood groups B and O experience higher…
2020 American Transplant Congress
Persistent Tertiary Hyperparathyroidism in the First Year after Kidney Transplantation is Associated with Calcium Phosphate Deposition in the Kidney Allograft
R. S. Avasare¹, N. K. Andeen², M. Stack¹, E. N. Dewey³, S. Rehman¹, M. Shindo⁴, J. Y. Lim³
¹Nephrology & Hypertension, OHSU, Portland, OR, ²Pathology, OHSU, Portland, OR, ³Surgery, OHSU, Portland, OR, ⁴Otolaryngology, OHSU, Portland, OR
*Purpose: To investigate risk factors for calcium phosphate deposition in the kidney allograft.*Methods: This is a single-institution, retrospective analysis of adult patients who underwent kidney…
2020 American Transplant Congress
Belatacept Conversion is Safe and Effective in Adolescent and Young Adult Kidney Transplant Recipients
A. Moudgil, C. Petyak, K. Sgambat
Nephrology, Children's National Med. Ctr., Washington, DC
*Purpose: Though tacrolimus (TAC) is a cornerstone of maintenance immunosuppression in kidney transplant recipients, some patients have significant side effects related to TAC. Conversion from…
2020 American Transplant Congress
Risk of Histological Relapse in Patients with Monoclonal Gammopathy of Renal Significance after Kidney Transplantation
A. Bentall¹, C. Heybeli², F. G. Cosio¹, M. El Ters¹, N. Leung¹, M. P. Alexander³
¹Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ²Department of Internal Medicine, Dokuz Eylul University, Izmir, Turkey, ³Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
*Purpose: There is increased recognition of Monoclonal Gammopathy of Renal Significance (MGRS) but data on kidney transplant (ktx)outcomes are lacking. We assessed KTX outcomes of…
2020 American Transplant Congress
The Impact of Preoperative Glucose Intolerance and Hypertension on the Living Kidney Donors
T. Hiramitsu¹, T. Tomosugi¹, K. Futamura¹, M. Okada¹, N. Goto¹, S. Narumi¹, K. Uchida², Y. Watarai¹
¹Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan, ²Department of Transplant Surgery, Masuko Memorial Hospital, Nagoya Aichi, Japan
*Purpose: Recently the mortality of living kidney donors was demonstrated to be significantly worse than that of healthy general population. However, the impact of preoperative…
2020 American Transplant Congress
Sirolimus Combined with Low-Dose Calcineurin Inhibitor in Kidney Transplant Recipients from Expanded Criteria Donors
J. Zhang, J. Lin, Y. Tian, W. Sun, L. Zhang
Beijing Friendship Hospital, Capital Medical University, Beijing, China
*Purpose: To evaluate the efficacy and safety of conversion from calcineurin inhibitor-based immunosuppressive regimen to sirolimus combined with low-dose calcineurin inhibitor in recipients with abnormal…