Am J Transplant, Volume 20, Suppl 3 Archives - Page 140 of 223 - ATC Abstracts

2020 American Transplant Congress
Tolerant Liver Transplant Patients Have Higher Level of Y RNA Fragments in the Circulation
C. Kuscu¹, A. Wolen¹, A. Bajwa¹, C. Kuscu¹, J. Eason², B. Ramaswami³, D. Maluf¹, G. Mazariegos³, G. Chalasani³, V. Mas¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ³Thomas E. Starzl Transplantation Institute, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Tolerance post transplantation continue to be the ultimate goal in transplantation. Circulating small RNAs are one of the best candidates for biomarker studies. To…
2020 American Transplant Congress
Diagnostic Method of Acute Kidney Rejection after Transplantation Using Metabolome Analysis via a Liquid Biopsy Approach
H. Iwamoto
Department of Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: At present, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy…
2020 American Transplant Congress
Assessment of Deceased Donor Kidney and Liver Surgical Recovery Error Rates
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: There is no nationally available data related to the incidence of surgical errors in deceased donor organ recoveries or its impact on organ discard…
2020 American Transplant Congress
Memory T Cell-Mediated Rejection is Regulated by FcγRIIB Expression on CD8⁺ T Cells
A. B. Morris, D. F. Pinelli, D. Liu, M. L. Ford
Emory University, Atlanta, GA
*Purpose: Donor-reactive memory T cells represent a potent immunologic barrier to long-term graft survival and tolerance induction. To identify novel pathways that regulate memory T…
2020 American Transplant Congress
The Impact of Multi-Organ Transplant Allocation Priority on Wait-Listed Isolated Kidney Transplant Candidates
S. Westphal¹, E. Langewisch¹, A. Robinson², A. Wilk², T. Plumb¹, R. Mullane¹, S. Merani¹, A. Hoffman¹, A. Maskin¹, C. Miles¹
¹University of Nebraska Medical Center, Omaha, NE, ²United Network for Organ Sharing, Richmond, VA
*Purpose: Multi-Organ Transplant (MOT) candidates involving a kidney receive higher allocation priority than kidney alone transplant (KAT) candidates. The increasing utilization of MOT has the…
2020 American Transplant Congress
High Volume, Highly Efficient, Outcome- Centric KPD Program: A Single Center Experience with Direct Exchange Based Strategies
K. Al Meshari, D. Broering, I. Alahmadi, S. Raza, T. Ali, A. Alabbassi, H. Alahdal, F. Alzayer
King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
*Purpose: We report our three and a half year experience with direct exchange (loop) based strategy single center KPD program.*Methods: 1. Inclusion of HLA and…
2020 American Transplant Congress
Frailty is Strongly Associated with Self-Reported Symptom Burden among Patients with Cirrhosis Undergoing Evaluation for Liver Transplantation
L. X. Deng, K. E. Bischoff, D. S. Kent, D. L. O’Riordan, S. Z. Pantilat, J. C. Lai
University of California, San Francisco, San Francisco, CA
*Purpose: Among patients with cirrhosis, frailty has most commonly been measured using instruments that focus on malnutrition, muscle wasting, and functional impairment. Little is known…
2020 American Transplant Congress
Comparison of Oropharyngeal Candidiasis Outcomes in Renal Transplant Recipients Receiving Nystatin or No Antifungal Prophylaxis
T. Q. Ky, L. Cotiguala, L. Fitzgerald, K. McMurry, J. Park, S. Tischer
Pharmacy, University of Michigan, Michigan Medicine, Ann Arbor, MI
*Purpose: Oropharyngeal candidiasis (OC) rate in the absence of antifungal prophylaxis has been reported as low as 7.4% after renal transplant. Due to perceived low…
2020 American Transplant Congress
The Liver Protects All? Donor Specific Antibody Formation in Heart-Liver Transplant Recipients
A. W. Rogers¹, T. N. Eagar², C. Pham¹, J. Krisl¹, B. J. Pierce¹, M. Moaddab¹, R. Ghobrial³, B. Trachtenberg⁴, A. Bhimaraj⁴, A. O. Gaber³
¹Department of Pharmacy, Houston Methodist Hospital, Houston, TX, ²Department of Pathology, Houston Methodist Hospital, Houston, TX, ³Department of Surgery, Houston Methodist Hospital, Houston, TX, ⁴Houston Methodist Hospital, Houston, TX
*Purpose: Donor specific antibodies (DSAs) are key in the development of antibody mediated rejection (AMR). Their role in decreased patient and graft survival has been…
2020 American Transplant Congress
Life-Supporting Pig Thymus Plus Kidney Transplantation Leads to Generation of New Baboon T-Cells and Swine-Specific Hyporesponsiveness
Y. Okumura¹, K. Takeuchi¹, Y. Ariyoshi¹, T. Pomposelli¹, L. Boyd¹, D. Alper¹, K. Miyake¹, K. Okubo¹, S. Arn¹, D. Ayares², M. Lorber³, M. Sykes¹, D. Sachs¹, K. Yamada¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Revivicor Inc., Blacksburg, VA, ³Lung BioTechnology PBC, Silver Spring, MD
*Purpose: We have achieved greater than 6-month survivals in baboons that received vascularized thymus plus kidney xenotransplants (VT+K XTx). We assessed the thymic function and…