ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Textbook Outcome: Definition and Analysis of a Novel Quality Measure in Kidney Transplantation

    S. E. Halpern1, D. Moris2, B. I. Shaw2, L. M. McElroy2, M. J. Ellis3, D. Sudan2, S. J. Knechtle2, B. H. Collins2, A. S. Barbas2

    1Duke University School of Medicine, Durham, NC, 2Department of Surgery, Duke University Medical Center, Durham, NC, 3Department of Medicine, Duke University Medical Center, Durham, NC

    *Purpose: Textbook outcomes (TO) is an emerging concept in surgery, which represents an effort to define a standardized, composite quality metric based on multiple postoperative…
  • 2020 American Transplant Congress

    Torque Teno Virus Level for Risk Stratification of Subclinical Graft Rejection at 12 Months after Kidney Transplantation – An Prospective Observational Cohort Study

    K. Doberer, E. Puchhammer, G. Böhmig, G. Bond

    Medical University Vienna, Vienna, Austria

    *Purpose: Non-invasive monitoring strategies are insufficient to detect patients at risk for subclinical graft rejection after kidney transplantation. The highly prevalent and non-pathogenic Torque Teno…
  • 2020 American Transplant Congress

    Integrated Multicohort Analysis of Transcriptome Profiles Identifies Blood Gene Signature to Distinguish Rejection from Infection in Patients with Solid Organ Transplants

    L. C. Murphy, A. Rao, M. Donato, P. Khatri

    School of Medicine, Stanford University, Stanford, CA

    *Purpose: Allograft rejection and infection are now leading causes of morbidity and mortality in transplant recipients. Current diagnosis relies on nonspecific markers of graft injury,…
  • 2020 American Transplant Congress

    Novel micro-RNA and Microbiome Signature Profiles as Biomarkers for Predicting the Risk of Autoimmune Type 1 Diabetes Development

    P. Chhabra1, G. Ricardo1, A. Spano2, V. Mas1, M. Timko2, K. Brayman1

    1Dept of Surgery, University of Virginia Health System, Charlottesville, VA, 2Dept of Biology, University of Virginia Health System, Charlottesville, VA

    *Purpose: To identify reliable microRNA (miRNA) and microbiome biomarkers for predicting risk of autoimmune beta-cell destruction in type 1 diabetes (T1D) and to investigate alterations…
  • 2020 American Transplant Congress

    Donor and Recipient Sex Affect Transplant Outcomes in an Age-Specific Fashion

    R. Maenosono1, Y. Nian1, J. Iske1, Y. Liu1, H. Azuma2, E. Milford3, S. G. Tullius1

    1Division of Transplant Surgery, Brigham and Women's Hospital, Boston, MA, 2Urology, Osaka Medical College, Osaka, Japan, 3Renal Division, Brigham and Women's Hospital, Boston, MA

    *Purpose: Donor and recipient sex impact transplant outcomes. The biology of sex-specific alloimmune responses has not been studied in detail.*Methods: Using clinical data from more…
  • 2020 American Transplant Congress

    Exosomes Derived from MSC Ameliorate Renal Ischemic-Reperfusion Injury Through Inhibiting Inflammation and Cell Apoptosis

    Y. Jia, M. Xu, T. Zhu

    Shanghai Key Laboratory of Organ Transplantation, Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China

    *Purpose: Investigate the underlying mechanism of mesenchymal stem cells (MSCs) on protection of renal ischemia reperfusion injury (IRI) .*Methods: Exosomes originated from MSCs (MSC-ex) were…
  • 2020 American Transplant Congress

    The Financial Concerns of Non-Directed (Altruistic) Living Kidney Donors – How Can We Improve the Donation Process?

    A. Maghen1, G. Mendoza1, G. B. Vargas1, S. E. Connor1, S. Nassiri1, L. Kwan1, E. L. Wood1, J. Lalezari1, S. Friedman1, A. D. Waterman2, S. George3, S. L. Maliski4, J. L. Veale1

    1Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 2Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 3Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, CA, 4Office of the Dean, University of Kansas Medical Center School of Nursing, Kansas City, KS

    *Purpose: The recent increase in non-directed (altruistic) kidney donors (NDDs) in the United States (U.S.) suggests their potential to help reduce the overburdened kidney transplant…
  • 2020 American Transplant Congress

    Thymoglobulin Induction in Kidney Transplant Recipients: A Single Center Experience Comparing 3 Mg/kg vs 5 Mg/kg Cumulative Dosing

    K. Progar1, S. January1, N. Nesselhauf1, J. Hagopian1, A. Malone2

    1Transplant, Barnes-Jewish Hospital, St. Louis, MO, 2Transplant Nephrology, Washington University, St. Louis, MO

    *Purpose: Beginning in 2016, our center implemented a protocol change to thymoglobulin (r-ATG) induction dosing in kidney transplant recipients at low rejection risk from 5…
  • 2020 American Transplant Congress

    The Effect of African American Race on Morbidity for Donors Undergoing Living Kidney Donation: A Single Center Study

    D. R. White, F. Desrosiers, S. Sultan, R. Craig-Schapiro, J. del Pizzo, S. Kapur, A. Watkins

    Kidney and Pancreas Transplantation, Weill Cornell Medicine, New York, NY

    *Purpose: To assess perioperative complication rates in African-Americans (AA) undergoing living donor nephrectomy in a large, single center program in the northeast.*Methods: We performed a…
  • 2020 American Transplant Congress

    Patient and Kidney Allograft Outcomes in Septuagenarians – A Single Center Experience

    G. Katz-Greenberg, A. Yadav, M. P. Martinez-Cantarin, P. Singh

    Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA

    *Purpose: Based on Scientific Registry of Transplant Recipients reporting, the proportion of patients 65 years or older on the kidney transplant (KT) waiting list has…
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