2020 American Transplant Congress
Single Cell Gene Profiling Highlights Novel B Cell Populations Associated with the Development of Bronchiolitis Obliterates Syndrome after Lung Transplantation
*Purpose: The occurence of bronchiolitis obliterans syndrome (BOS) accounts for a poor long term prognosis after lung transplantation (LTx). Despite immunosuppressive T cell-targeting therapies the…2020 American Transplant Congress
Creation of a Low-Cost Kidney Transplant Surgery Simulator and Survey of its Utility for Education
Department of Surgery, Saint Louis University, Saint Louis, MO
*Purpose: Surgical skills education in transplant surgery is challenging as center-specific outcomes are scrutinized and trainees’ exposure to the sub-specialty is decreasing. Simulation could overcome…2020 American Transplant Congress
Anti-HLA IgM Antibodies are Unaffected by Imlifidase (IdeS) Treatment
*Purpose: The immunoglobulin G (IgG)-degrading cysteine protease, imlifidase (IdeS) is an IgG endopeptidase under development as a rapid desensitization treatment in kidney transplantation. Imlifidase is…2020 American Transplant Congress
Domino Transplantation – Expanding the Liver Donor Pool to the Pediatric Recipient
*Purpose: Background: Maple syrup urine disease (MSUD) is an inherited autosomal recessive metabolic disorder of amino acid metabolism, caused by a defect of the branched-chain…2020 American Transplant Congress
Mycophenolic Acid Exposure in Young, Middle Age and Older Stable Renal Transplant Recipients
*Purpose: Mycophenolic acid (MPA) is an essential drug in maintenance immunosuppressive regimens. In spite of increased kidney transplants in the elderly, limited pharmacokinetic investigations comparing…2020 American Transplant Congress
Torque Teno Virus for Risk Stratification of Graft Rejection and Infection in Kidney Transplant Recipients – A Prospective Observational Trial
Medical University Vienna, Vienna, Austria
*Purpose: The non-pathogenic and ubiquitous Torque Teno virus (TTV) is associated with immunosuppression in solid organ transplant recipients. This trial was designed to assess the…2020 American Transplant Congress
Type 1 Innate Lymphoid Cells Are Critical Pro-Inflammatory Effector Cells in a Fatty Liver Mouse Model of Ischemia-Reperfusion Injury
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis and immune regulation through the activation…2020 American Transplant Congress
Preformed Anti-HLA Donor-Specific Antibodies Immunological Risk Assessment: The Importance of HLA Antibody Locus-Specificity
*Purpose: The screening of preformed donor-specific HLA antibodies (pfDSA) by single antigen bead assays has increased the complexity of pre-transplant patient risk stratification. We evaluated…2020 American Transplant Congress
Paired-Donor Kidney Exchange Has Comparable Early Graft Function to Directed Living Donor
Transplant Surgery, University of Virginia, Charlottesville, VA
*Purpose: Living kidney donation in the United States is associated with improved graft and patient survival. However, there is minimal data on graft function in…2020 American Transplant Congress
Impact of Enhanced Recovery after Surgery Protocols on Robotic Living Kidney Donor Outcomes: A Single Center Experience
Virginia Commonwealth University, Richmond, VA
*Purpose: Traditional management of living donor nephrectomies includes intraoperative volume loading to maintain renal perfusion and urine output. Recently our center initiated fluid restriction as…
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