ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Missing Self Increases the Incidence of Microvascular Inflammation after Kidney Transplantation

    J. Callemeyn1, A. Senev2, M. Coemans1, E. Lerut3, B. Sprangers1, D. Kuypers1, A. Koenig4, O. Thaunat4, M. Emonds2, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Histocompatibility and Immunogenetics Laboratory, Red Cross-Flanders, Mechelen, Belgium, 3Imaging and Pathology, KU Leuven, Leuven, Belgium, 4INSERM U1111, Université Claude Bernard Lyon I, Lyon, France

    *Purpose: Anti-HLA donor-specific antibodies (HLA-DSA) are often absent in serum of kidney allograft recipients with biopsies demonstrating microvascular inflammation (MVI), the histological hallmark of antibody-mediated…
  • 2020 American Transplant Congress

    Timing of Bariatric Surgery for Obese Liver Transplant Candidates

    R. A. Choudhury1, D. Yoeli2, G. Hoeltzel3, H. B. Moore2, H. Yaffe2, K. R. Dumon4, N. N. Williams4, P. L. Abt5, K. D. Conzen2, J. J. Pomposelli2, E. A. Pomfret2, T. L. Nydam2

    1Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Denver, CO, 2Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 3Thomas Jefferson University Hospital, Philadelphia, PA, 4Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA, 5Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA

    *Purpose: The timing of bariatric surgery for obese liver transplant candidates remains controversial. Surgery prior to transplant may improves one’s chance of receiving a transplant,…
  • 2020 American Transplant Congress

    The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients

    H. Hirao1, T. Ito1, B. V. Naini1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
  • 2020 American Transplant Congress

    A Stroke Volume-Based Fluid Resuscitation Protocol Decreases Vasopressor Support and Increases Organ Yield in Brain-Dead Donors

    G. F. Marklin

    Mid-America Transplant, St Louis, MO

    *Purpose: Brain-dead donors are frequently hypovolemic and hypotensive requiring vasopressor support. The goal of fluid resuscitation is to increase perfusion and oxygen delivery and avoid…
  • 2020 American Transplant Congress

    Impact of Ozone Exposure of Lung Donors and Recipients on All-Cause Mortality after Lung Transplant

    T. Egan1, S. Arunachalam2, C. Chang2, P. Strassle1

    1Surgery, UNC at Chapel Hill, Chapel Hill, NC, 2Institute of the Environment, UNC at Chapel Hill, Chapel Hill, NC

    *Purpose: A Belgian study found proximity to a motorway increased risk of bronchiolitis obliterans syndrome after lung transplant (LT). Using zip codes as a surrogate…
  • 2020 American Transplant Congress

    T and B Lymphocyte Dynamics after Genetically-Modified Pig-To-Baboon Kidney Xenotransplantation with an Anti-CD40mAb-Based Immunosuppressive Regimen

    A. Jagdale1, H. Iwase1, H. Nguyen1, T. Yamamoto1, D. Ayares2, D. Anderson1, D. Eckhoff1, D. Cooper1, H. Hara1

    1Surgery, University of Alabama at birmingham, Birmingham, AL, 2Revivicor, Blacksburg, VA, VA

    *Purpose: We have evaluated recovery of T and B lymphocytes and their subsets after depletion by anti-thymocyte globulin (ATG) and an anti-CD20mAb (Rituximab), followed by…
  • 2020 American Transplant Congress

    One Year of COIIN Outcomes: Did Cohorts A and B Maintain Graft Survival?

    J. Foutz, R. J. Carrico, K. Sisaithong, H. Tosoc-Haskell, D. Klassen

    United Network for Organ Sharing, Richmond, VA

    *Purpose: The Collaborative Innovation and Improvement Network (COIIN) was a 3-year OPTN project aimed at increasing the utilization of kidneys with a kidney donor profile…
  • 2020 American Transplant Congress

    Empowering Recipients Through a Champion Program: A Life Saving Initiative

    C. L. Rochon, D. Woch, K. Rancourt, O. K. Serrano, A. K. Asamoah

    Transplantation, Hartford Hospital, Hartford, CT

    *Purpose: Our purpose was to increase access to living donor kidney transplantation for patients referred at our center. With our interventions, our patients and their…
  • 2020 American Transplant Congress

    Living Donor Liver Transplantation for Unresectable Liver Confined Colorectal Liver Metastases: A North American Experience

    L. I. Ruffolo, K. Dokus, M. Larye, J. Errigo, J. Bhoely, R. Dunne, M. Levstik, B. Al-Jadaibi, K. Tomiyama, R. Hernandez-Alejandro

    Surgery, University of Rochester Medical Center, Rochester, NY

    *Purpose: Colorectal cancer is the third leading cause of cancer related death, and 50% of patients will either present with synchronous or develop colorectal liver…
  • 2020 American Transplant Congress

    Donor Derived Transmissions 2018: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)

    M. Michaels1, B. Plucinski2, E. Ward2, L. Strasfeld1, M. Malinis1, C. Ho1, L. Danziger-Isakov1, J. Bucio1, G. Berry1, M. Rana1, C. Marboe1, S. Aslam1, R. Razonable1, S. Pouch1, G. F. Marklin1, J. Levitsky1, D. Levine1, A. Agarwal1, R. LaHoz1

    1OPTN DTAC, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: The OPTN DTAC, a multidisciplinary group, evaluates potential donor derived transmission events (PDDTE), mostly infections (I) & malignancies (M), to assess the likelihood of…
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