Am J Transplant, Volume 20, Suppl 3 Archives - Page 135 of 223 - ATC Abstracts

2020 American Transplant Congress
Machine Learning Model Outperforms Linear Regression Models for 1- and 3-Year Post-Transplant Survival: Is This the Future?
R. W. Pettit¹, S. J. Corr², J. Havelka³, A. Rana¹
¹Baylor College of Medicine, Houston, TX, ²Interdisciplinary Surgical Technology and Innovation Center, Baylor College of Medicine, Houston, TX, ³InformAI, Houston, TX
*Purpose: Modeling is essential for regulatory oversight and risk stratification in clinical practice. Our hypothesis was that machine learning models would be superior to linear/logistic…
2020 American Transplant Congress
Estrogen Receptor Beta Deletion in the Vascular Endothelium is Protective in Renal Ischemia Reperfusion Injury
L. Krumeich¹, P. Hernandez¹, C. O'Brien¹, S. Concors¹, Z. Wang¹, G. Ge¹, W. Hancock², M. Levine¹
¹Hospital of University of Pennsylvania, Philadelphia, PA, ²Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Renal ischemia reperfusion injury (IRI) is a major contributor to early allograft dysfunction (EAD) in kidney transplantation. We previously identified lower rates of EAD…
2020 American Transplant Congress
AIPCs Home to and Engraft in the Pancreas When Injected Intravenously
J. B. Pollett¹, N. Thai²
¹Imagine Pharma, Pittsburgh, PA, ²Allegheny Health Network, Pittsburgh, PA
*Purpose: AIPCs (Activated Islet Proliferating Cells) are a recently developed cell population generated from isolated islets of mice and humans. AIPCs are over 65% CD133-,…
2020 American Transplant Congress
The Fibrinogen-Like Protein 2 Molecule Influences the Development of Thymic Regulatory T-Cells
C. Lam¹, S. Moshkelgosha¹, G. A. Levy², A. Chruscinski³, S. C. Juvet⁴
¹Latner Thoracic Surgery Research Laboratories, University Health Network, Toronto, ON, Canada, ²Multi Organ Transplant Program, University Health Network, Toronto, ON, Canada, ³Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON, Canada, ⁴Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada
*Purpose: Transplantation is the primary treatment for patients with end-stage organ failure. However, long-term outcomes are limited by immunosuppressant toxicities and chronic graft rejection. Identifying…
2020 American Transplant Congress
Efficacy of Generic Sofosbuvir and Branded Daclatasvir Compared to Sofosbuvir and Ledipasvir Combination in the Treatment of Genotype 4 Hepatitis C Virus
H. Joharji, D. Alkortas, A. Ajlan, E. Devol, M. Ahmed, F. Aba Al-Khail, H. Elsiesy, M. Alsebayel, H. Alashgar, M. Alquaiz, W. Alhamoudi, A. Almoshishir, A. Aljedai
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: Genotype 4 HCV is the most common genotype in Saudi Arabia and the Middle East. Management of HCV has shifted in the last few…
2020 American Transplant Congress
Post-Transplant Rebound and Not Baseline Anti-A Titers are Associated with Acute Antibody-Mediated Rejection in A₂– to B/O Incompatible Kidney Transplantation
V. Kumar, D. Mompoint-Williams, M. Marques, P. MacLennan, M. Mustian, J. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Decreased antigen expression among blood group A subtype 2 (A2) donor kidneys allows these organs to be considered as universal donors; under the new…
2020 American Transplant Congress
Bariatric Surgery to Improve Candidacy for Kidney Transplantation: A Systematic Review and Meta-Analysis
J. Purvis¹, S. Mehta¹, R. Stahl¹, J. Grams¹, M. Hanaway¹, D. Anderson¹, C. Young¹, R. Cannon¹, C. Lewis¹, N. Terrault², J. Locke¹, B. Orandi¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Southern California, Los Angeles, CA
*Purpose: There is a growing epidemic of obesity in patients with end stage kidney disease in need of kidney transplant, paralleling the general population. Most…
2020 American Transplant Congress
Significance of DSA Clearance in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients on 1 Year Outcomes: Interim Results from PARAMOUr “Pediatric Renal AMr Outcomes” Study
I. Ashoor¹, R. Garro², S. Solomon³, A. Jain⁴, M. Kallash⁵, K. Twombley⁶
¹LSHUSC Children's Hospital New Orleans, New Orleans, LA, ²Emory University School of Medicine, Atlanta, GA, ³New York Medical College, Valhalla, NY, ⁴Wayne State University School of Medicine, Detroit, MI, ⁵Nation Wide Children's Hospital, Columbus, OH, ⁶Medical University of South Carolina, Charleston, SC
*Purpose: Little is known about how donor specific antibody (DSA) clearance correlates with outcomes in pediatric antibody mediated rejection (AMR). There is also little data…
2020 American Transplant Congress
Delayed Graft Function Adversely Affects Long-Term Survival for Kidney Recipients after Non-Renal Solid-Organ Transplantation
J. A. Reyes, C. Blanton, M. Eerhart, G. Leverson, P. Chlebeck, Y. Yankol, L. Fernandez
Surgery, University of Wisconsin, Madison, WI
*Purpose: End-stage renal disease (ESRD) frequently develops after nonrenal solid-organ transplantation, increasing the number of patients with a prior heart, liver or lung transplant on…
2020 American Transplant Congress
Long-Term Outcomes in Recipients of Allografts from Living Kidney Donors with Hypertension
F. Al Ammary¹, S. Yu², A. Muzaale², L. Luckmini², D. C. Crews¹, D. Brennan¹, D. Segev², A. B. Massie²
¹Medicine, Johns Hopkins, Baltimore, MD, ²Surgery, Johns Hopkins, Baltimore, MD
*Purpose: Allografts from living kidney donors may “carry” subclinical pathological abnormalities to the recipient and thus lead to adverse clinical outcomes. Because one mechanism underlying…