Am J Transplant, Volume 20, Suppl 3 Archives - Page 132 of 223 - ATC Abstracts

2020 American Transplant Congress
Laparoscopic Donor Nephrectomy – Call for a Selective Radical Approach
A. Vijay¹, M. Cooper², J. Verbesey², P. Abrams², S. Yi², S. Ghasemian²
¹Transplant Surgery, University of North Carolina, Chapel Hill, NC, ²Transplant Surgery, Medstar Georgetown Transplant Institute, Washington, DC
*Purpose: Introduction: Retrieval of kidneys in obese donor with excessive peri-renal fat has been reported to be more technically challenging with increased incidence of surgical…
2020 American Transplant Congress
Time-Zero Histology Correlates with Donor Characteristics but Does Not Predict Short-Term Outcomes in Kidney Transplantation
S. Raza, G. Agarwal, D. Anderson, M. Deierhoi, H. Fatima, M. Hanaway, J. Locke, P. MacLennan, B. Orandi, C. Young, R. Mannon, M. Seifert
University of Alabama School of Medicine, Birmingham, AL
*Purpose: Time-zero biopsies provide important information about baseline histology but their clinical utility compared to other non-invasive predictors is unclear. Our center performs universal time-zero…
2020 American Transplant Congress
HLA-DQ Plays an Important Role in Graft Survival in African American Transplant Recipients
L. M. Rebellato¹, W. Irish², D. Leeser², J. Tuttle², C. E. Haisch²
¹Pathology, The Brody School of Medicine at ECU, Greenville, NC, ²Surgery, The Brody School of Medicine at ECU, Greenville, NC
*Purpose: Our kidney transplant (KTx) program serves a medically underserved and racially diverse area of a southern state. The purpose of this study was to…
2020 American Transplant Congress
Cell-Free DNA (cfDNA) is Released by Necroptosis and Promotes Kidney Ischemia Reperfusion Injury
A. C. Dionne
Microbiology and Immunology, Western University, London, ON, Canada
*Purpose: Transplantation is invariably associated with ischemia reperfusion injury (IRI) which causes organ dysfunction. IRI is also directly linked to several forms of programmed cell…
2020 American Transplant Congress
Vesicle-Associated Tweak is Increased During Acute Cellular Rejection and Contributes to Endothelial Inflammation
O. Gidlof, J. Sadrian, M. Grossi, S. Alcevska, J. Lundgren, G. Rådegran, G. Smith
Cardiology, Lund University, Lund, Sweden
*Purpose: Extracellular vesicles (EVs) are released from immune cells upon activation and play direct roles in allograft tolerance and rejection, in part through delivery of…
2020 American Transplant Congress
Oral Administration of Nano-Sized Silicon Particles Regulates Gene Expression Related to Oxidative Stress and Attenuates Rat Renal Ischemia Reperfusion Injury
M. Kawamura¹, R. Imamura¹, Y. Kobayashi², A. Taniguchi¹, S. Nakazawa¹, T. Kato¹, T. Abe¹, H. Kobayashi², N. Nonomura¹
¹Department of Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, ²The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, Japan
*Purpose: Organ ischemia reperfusion injury (IRI) is unavoidable in kidney transplantation and induces reactive oxygen species and causes organ damage. Although the effectiveness of hydrogen…
2020 American Transplant Congress
Human, Monkey Transplant Tolerance and IL35 “Exokine
W. J. Burlingham¹, E. Jankowska-Gan², D. Lema², J. H. Fechner², J. A. Sullivan², D. B. Kaufman²
¹University of Wisconsin, Madison, WI, ²Surgery, University of Wisconsin, Madison, WI
*Purpose: Studies in B6 (H2b) mice tolerized to CBA (H2k) have shown that induced allospecific Tregs make 2 very different forms of immunoregulatory cytokines: 1)…
2020 American Transplant Congress
Thymoglobulin Dose and Incidence of Biopsy Proven Acute Rejections in the Early Post Transplant Period
K. Shimko, K. Schonder, D. Jorgensen, K. Kalra, A. Cherukuri, R. Mehta, I. Melgarejo, P. Sood, S. Hariharan, R. Mehta
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Optimal dosing of thymoglobulin (ATG) for induction has not been well defined. Our protocol aims for 5-6mg/kg cumulative dose divided over 4 doses. However,…
2020 American Transplant Congress
When CPRA Zero is Not the Hero: Does KAS Disadvantage Unsensitized Relisted Patients?
M. Casey, Z. Su, M. Mohamed Ahmed, D. Taber, E. Weeda, T. Morinelli, P. Mauldin, K. Soliman, M. A. Posadas-Salas, V. Rao, D. DuBay
Medical University of South Carolina, Charleston, SC
*Purpose: Since the 2014 Kidney Allocation System (KAS) changes, patients with a very high calculated panel reactive antibody (CPRA) have received greater priority in deceased…
2020 American Transplant Congress
Impact of Focal Cortical Necrosis (CN) in Preimplantation Biopsy (PBx) on Outcomes after Deceased Donor Kidney Transplantation
S. S. Nair, J. Ninan, R. Heilman, K. Reddy, M. Smith
Mayo Clinic, Phoenix, AZ
*Purpose: The data on outcomes of focal CN in PBx after deceased donor transplantation is sparse. We studied the prognostic value of focal CN on…