2020 American Transplant Congress
Role of B-Cell Subsets in Allograft Rejection in Intestinal Transplantation
Transplant Institute, MedStar Georgetown University, Washington, DC
*Purpose: While B-cells contribute to allograft rejection by presenting antigens to T-cells and by producing donor-specific antibodies (DSAs) and various cytokines, their pathophysiology in transplant…2020 American Transplant Congress
Early Post-Transplant Infusion of Ex Vivo-Expanded Autologous Polyclonal Regulatory T Cells (Treg) Prolongs Kidney Allograft Survival in Non-Lymphodepleted, CTLA4Ig-Treated Rhesus Monkeys
Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: Rodent studies have demonstrated the utility of regulatory T cell (Treg) infusion for the promotion of tolerance to organ allografts. Here, we evaluated the…2020 American Transplant Congress
End-Hypothermic Oxygenated Machine Perfusion after Static Cold Storage versus Static Cold Storage Alone in Kidneys from Extended Criteria Brain-Dead Donors: An International Randomized Controlled Trial
*Purpose: A prospective, randomized, single-blinded, multicenter trial comparing the effect of short-term 'in house' oxygenated hypothermic machine preservation (End-HMPO2) following static cold storage (SCS) versus…2020 American Transplant Congress
Pulmonary Hypertension is Associated with Inferior Graft and Patient Survival after Kidney Transplantation
Johns Hopkins Hospital, Baltimore, MD
*Purpose: Pulmonary hypertension (PH) is increasingly recognized among patients with chronic kidney disease largely driven by left heart failure, high cardiac output, hypoxic lung diseases…2020 American Transplant Congress
Long-Term Outcomes of Stone Former Donors at the University of Minnesota
1University of Minnesota, Minneapolis, MN, 2Surgery, University of Minnesota, Minneapolis, MN
*Purpose: As the National kidney shortage continues to rise, efforts to expand the donor pool by utilizing living kidneys from stone-forming donors have become widely…2020 American Transplant Congress
A Multidisciplinary Protocol for the Management of Hyponatremia at the Time of Liver Transplantation is Associated with Reduced Post-Transplant Neurologic Complications
*Purpose: The primary purpose of this study was to assess whether implementation of a multidisciplinary protocol (Figure 1) aimed at limiting rapid changes in serum…2020 American Transplant Congress
Compliance with OPTN Living Kidney Donor Follow-Up Policy Remains Low
1University of North Carolina, Chapel Hill, NC, 2Johns Hopkins, Baltimore, MD
*Purpose: OPTN implemented a policy in 2013 that required all centers to perform 6-, 12-, and 24-month living donor follow-up (LDF). Early compliance with this…2020 American Transplant Congress
Single Cell Analysis of Living Donor Kidneys Characterizes Resident Parenchymal and Immune Populations in Male and Female Donors
*Purpose:Understanding the molecular profiles and individual contributions of kidney parenchymal and resident/infiltrating immune cells during homeostasis would facilitate development of treatments for kidney graft disease.…2020 American Transplant Congress
Role of Cross-Dressing in Kidney Transplantation
Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Activation of host T cells that mediate allograft rejection is relied on dendritic cells (DCs) presenting alloantigens to T cells. Our recent study revealed…2020 American Transplant Congress
Waitlist-Conditioned Transplant Rate is Not an Appropriate Metric for Benchmarking Access to Kidney Transplantation
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Transplant rate is used as a primary metric of center performance as reported by the SRTR. However, the calculation of transplant rate can be…
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