ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Perioperative Coagulation Profile of Hepatocellular Carcinoma During Liver Transplantation Compared to Patients with Non-Malignant Disease: A Cause or Association for Decreased Blood Product Utilization During Liver Transplantation?

    H. B. Moore, E. Pomfret, J. Pomposelli, C. Walker, R. Choudhury, H. Yaffe, M. Wachs, T. Bak, K. Conzen, M. Adams, T. Pshak, T. L. Nydam

    University of Colorado, Aurora, CO

    *Purpose: Hepatobiliary malignancies have been associated with hyper-coagulability. However, the impact of hepatocellular carcinoma (HCC) on coagulation during liver transplantation remains less clear. We hypothesize…
  • 2020 American Transplant Congress

    The Impact of Purposeful Reductions in Immunosuppression on Clinical Outcomes in Kidney Transplantation

    K. Foster, H. Perkins, N. Patel, C. Perez, N. Pilch, H. Meadows, F. Bartlett, V. Rao, M. Casey, M. Posadas Salas, K. Soliman, J. McGillicuddy, D. Taber

    MUSC Health, Charleston, SC

    *Purpose: Reductions to immunosuppressive therapy (IS) are often made due to infection or other IS intolerances, but little is known of impact of these reductions…
  • 2020 American Transplant Congress

    Pre-Renal Transplant Education and Psychosocial Evaluation Positively Impacts Post-Transplant Medication Adherence

    M. Jesse1, D. Kim1, A. Patel1, R. Patil1, S. Bhavsar1, S. Desai1, K. Gartrelle1, A. Eshelman1, E. Fleagle1, D. Nicholson1, E. Clifton2

    1Henry Ford Health System, Detroit, MI, 2University of Michigan, Ann Arbor, MI

    *Purpose: An essential element of the organ transplant evaluation process is the preparation of transplant candidates and their social supports. However, approaches to this process…
  • 2020 American Transplant Congress

    Role of APC Subsets in Rejection and Graft-Versus-Host-Disease in Intestinal Transplantation

    H. Dhani, N. Svetlicky, J. Kang, S. Moturi, A. Duttargi, K. Khan, C. Matsumoto, T. S. Fishbein, A. Kroemer

    Transplant Institute, MedStar Georgetown University, Washington, DC

    *Purpose: Intestinal transplantation (ITx) is arguably the most immunogenic and complex organ transplantation, often accompanied with high rates of allograft rejection (AR) and graft-versus-host disease…
  • 2020 American Transplant Congress

    Treg-Lymphatic Interfaces: Unique Molecular Structures for Cell-Cell Interactions During Migration

    C. M. Paluskievicz, W. Piao, Y. Xiong, J. S. Bromberg

    U of Maryland, Baltimore, MD

    *Purpose: To promote transplant tolerance, T regulatory cells (Treg) must enter the afferent lymphatic vasculature by migrating across lymphatic endothelial cells (LECs), and then home…
  • 2020 American Transplant Congress

    Exposure to Tacrolimus Trough Levels Below 6ng/ml During the First Year is Associated with Inferior Kidney Graft Survival

    T. Agur, B. Rozen-Zvi, R. Rahamimov

    Department of Nephrology and Hypertension, Rabin Medical Center, Petah Tikva, Israel

    *Purpose: Accumulating data indicates that sub-therapeutic levels of calcineurin inhibitors are associated with long-term graft loss. However, while widely used tacrolimus (TAC) was shown to…
  • 2020 American Transplant Congress

    Glomerular Filtration Rate Based on Cystatin C Provides the Best Prediction of Cardiovascular Events and Mortality Compared to Measured GFR and Creatinine Based GFR in Kidney Transplant Recipients

    L. Galapia1, J. Lieske2, A. Rule2, H. Amer2, N. Zhang1, D. Butterfield1, M. Keddis1

    1Mayo Clinic, Scottsdale, AZ, 2Mayo Clinic, Rochester, MN

    *Purpose: GFR estimated by cystatin C (CysC) is a better predictor of cardiovascular (CV) events and mortality compared to eGFR by creatinine (Cr) in native…
  • 2020 American Transplant Congress

    Predonation Hypertension and Early Postdonation Systolic Blood Pressure among Older Living Kidney Donors

    F. Al Ammary1, A. D. Muzaale2, D. C. Brennan1, D. L. Segev2, A. B. Massie2

    1Medicine, Johns Hopkins University, Baltimore, MD, 2Surgery, Johns Hopkins University, Baltimore, MD

    *Purpose: One mechanism underlying predonation hypertension in older (age≥50) living kidney donors is a reduced number of nephrons. The 50% nephron mass reduction associated with…
  • 2020 American Transplant Congress

    Safety and Immunogenicity of Adjuvanted Recombinant Subunit Herpes Zoster Vaccine in Lung Transplant Recipients

    C. Hirzel1, V. H. Ferreira1, A. G. L’Huillier1, T. Ku1, M. Ierullo1, C. Miao2, D. S. Schmid2, J. Tikkanen1, L. G. Singer1, A. Humar1, D. Kumar1

    1University Health Network, Toronto, ON, Canada, 2CDC, Atlanta, GA

    *Purpose: The new adjuvanted subunit recombinant herpes zoster vaccine (RZV; Shingrix™) may have potential utility in transplant patients for the prevention of shingles, but there…
  • 2020 American Transplant Congress

    Did the 250 Nautical Mile Circle Work? Geographic Disparities in Lung Transplantation Before and after the Policy Change

    M. Kosztowski1, Y. Yu2, A. Massie2, D. L. Segev2, S. E. Gentry2

    1University of Iowa, Iowa City, IA, 2Johns Hopkins, Baltimore, MD

    *Purpose: In November 2017, the lung allocation policy was challenged in court due to concern that candidates living in New York City were being disadvantaged…
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