Am J Transplant, Volume 20, Suppl 3 Archives - Page 127 of 223 - ATC Abstracts

2020 American Transplant Congress
Co-Stimulatory Blockade Immunosuppression Facilitates Lung Allograft Acceptance Through an Increase in Local IL-5 Production by Type 2 Innate Lymphoid Cells
Y. Guo, Z. Mei, A. Hata, B. Mahgoub, D. Li, A. Manafi, A. Banerjee, A. Gelman, D. Kreisel, A. Krupnick
Surgery, University of Virginia, Charlottesville, VA
*Purpose: We have recently demonstrated that co-stimulatory blockade (CSB)-induced mouse lung allograft acceptance depends on a rapid influx of eosinophils that function to downregulate T…
2020 American Transplant Congress
Eplet Mismatch Not Correlated with Antibody Mediated Rejection or Allograft Loss Among Kidney Transplant Recipients with De Novo Donor Specific Antibody
A. Basu¹, W. Jiqiu², A. Bentall², M. Gandhi², B. Dukek², N. Henderson², C. Schinstock²
¹Emory Healthcare, Atlanta, GA, ²Mayo Clinic, Rochester, MN
*Purpose: Eplet mismatches are associated with development of de novo DSA (dnDSA) in kidney transplant recipients. However, it remains unclear how the degree of eplet…
2020 American Transplant Congress
Normothermic Machine Perfusion of Extended Criteria Donor Livers: Identification of Protein Biomarkers Predictive of Graft Viability and Post-Transplant Complications
L. L. Wallace¹, J. Attard¹, Y. Boteon¹, R. Laing¹, J. Yu², T. Perera³, D. Mirza³, H. Mergental³, S. Afford¹
¹Centre for Liver and Gastrointestinal Research, University of Birmingham and the NIHR Biomedical Research Centre, UHB NHS Foundation Trust, Birmingham, United Kingdom, ²School of Biosciences, Advanced Mass Spectrometry Facility, University of Birmingham, Birmingham, United Kingdom, ³Liver Unit, The Queen Elizabeth Hospital, Birmingham, United Kingdom
*Purpose: The Viability Testing and Transplantation of mArginal donor Livers Clinical Trial (VITTAL) demonstrated the capacity of Normothermic Machine Perfusion (NMP) to increase the proportion…
2020 American Transplant Congress
The Experience of 1000 Cases of Hand Assisted Laparoscopic Donor Nephrectomy for Living Donor Kidney Transplantation
T. Hiramitsu¹, T. Tomosugi¹, K. Futamura¹, M. Okada¹, N. Goto¹, S. Narumi¹, K. Uchida², Y. Watarai¹
¹Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan, ²Masuko Memorial Hospital, Nagoya Aichi, Japan
*Purpose: Due to the increasing number of kidney transplant candidates, living donor kidney transplantation becomes more necessary. For living donor kidney transplantation, safe and efficient…
2020 American Transplant Congress
Predicting Renal Graft Function Post Transplantation Using Clinical and Biological Features Supported by Machine Learning Algorithms
Y. Gao¹, Y. Cui¹, C. Kuscu², C. Kuscu², L. Gallon³, A. Bajwa², E. Akalin⁴, J. D. Eason², D. Maluf², V. Mas²
¹Department of Genetics, University of Tennessee Health Science Center, Memphis, TN, ²Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ³Northwestern University, Chicago, IL, ⁴Albert Einstein Medical College, New York, NY
*Purpose: Predicting renal function post transplantation is a frequent challenge impacting physician decisions and patient quality of life. We aimed to develop a composite score…
2020 American Transplant Congress
Efficacy and Safety of Single-Dose Rabbit Anti-Thymocyte Globulin versus Basiliximab Induction among Pediatric Kidney Transplant Recipients
L. Porini Custodio, S. Stopa Martins, L. Almeida Viana, M. Pontello Cristelli, M. Rika Nakamura, H. Tedesco-Silva, J. Medina-Pestana
Hospital do Rim, Sao Paulo, Brazil
*Purpose: Induction therapy is a standard component of kidney transplant immunosuppression protocols. However, in the pediatric population, there are still uncertainties about the ideal induction…
2020 American Transplant Congress
Pharmacokinetic Evaluation of a De Novo Envarsus XR® (tacrolimus Extended Release) Dosing Strategy in Kidney Transplant Recipients
J. Schulte¹, C. Kane¹, K. Cunningham¹, C. D'Agostino¹, M. Kapugi¹, A. Novak¹, A. Shetty², J. Leventhal², J. Friedewald²
¹Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ²Division of Transplantation, Northwestern Memorial Hospital, Chicago, IL
*Purpose: Envarsus XR® is a once-daily tablet formulation of tacrolimus recently approved for the prophylaxis of organ rejection in de novo kidney transplant recipients (KTx).…
2020 American Transplant Congress
Sleeve Gastrectomy Compared with Gastric Bypass for Morbidly Obese Liver Transplant Candidates: A Decision Analysis
R. A. Choudhury¹, D. Yoeli¹, G. Hoeltzel², H. B. Moore¹, H. Yaffe¹, K. R. Dumon³, N. N. Williams³, P. L. Abt⁴, K. D. Conzen¹, J. J. Pomposelli¹, E. A. Pomfret¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: The use of bariatric surgery has increased for morbidly obese liver transplant candidates for whom placement on the waitlist is often restricted until they…
2020 American Transplant Congress
Karnofsky Performance Status Significantly Increases Waitlist Mortality among Different Grades of Acute on Chronic Liver Failure
A. Ashhab¹, R. Wong², V. Sundaram¹
¹Cedars Sinai Medical Center, Los Angeles, CA, ²Alameida Health System, Oakland, CA
*Purpose: Acute on chronic liver failure (ACLF) is a condition associated with high waitlist mortality and graded according to the number of organ system failures…
2020 American Transplant Congress
Induction Immunosuppression with Thymoglobulin May Improve Graft Outcomes without Increasing a Risk for Infection in Patients Undergoing Liver Transplantation Alone
M. Henry¹, T. Kitajima², J. Konel¹, S. Yeddula², M. Rizzari², K. Collins², D. Moonka², A. Yoshida², M. Abouljoud², S. Nagai³
¹Wayne State University School of Medicine, Detroit, MI, ²Henry Ford Hospital, Detroit, MI, ³Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Immunosuppression protocols for liver transplant (LT) vary between institutions and roles of induction immunosuppression in LT remain controversial. The aim of this study was…