ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Liver Plasmacytoid Dendritic Cells Express High Levels of DAP12, TREM2 and PD-L1 and Promote Effector T Cell Exhaustion and Augmented Treg Responses in Spontaneous Liver Transplant Tolerance

    R. Nakano, O. Yoshida, S. Kimura, D. Geller, A. Thomson

    University of Pittsburgh, Pittsburgh, PA

    *Purpose: The precise mechanisms of liver transplant tolerance are yet to be elucidated. Non-conventional plasmacytoid dendritic cells (pDCs) are thought to promote immune regulation, including…
  • 2020 American Transplant Congress

    A Machine-Learning Approach for Estimating Likelihood of Transplant Benefit from Older-Donor Kidneys

    T. Pruett1, P. Martin2, D. Gupta3

    1University of Minnesota, Minneapolis, MN, 2University of Texas, Austin, TX, 3McCombs School of Business, University of Texas, Austin, TX

    *Purpose: There is a shortage of transplantable kidneys in the US. Yet, the discard rate among older donors (55+) is approx. 38% per year. The…
  • 2020 American Transplant Congress

    Belatacept Provides Superior Inhibition of Donor Specific Antibody Formation in Kidney Transplant Recipients with Acute Rejection

    O. Cristea, C. Larsen, I. Badell

    Emory Transplant Center, Emory University School of Medicine, Atlanta, GA

    *Purpose: The factors responsible for chronic renal allograft dysfunction and premature graft loss are incompletely understood and likely multifactorial. Immunologic injury partially attributable to the…
  • 2020 American Transplant Congress

    Biliary Reconstructionwith High Biliary Radicals is Safe Option for Multiple Graft Bile Ducts in Right Lobe Living Donor Liver Transplantation

    J. Kim, D. Choi, E. Jwa

    Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of

    *Purpose: Multiple small size donor bile ducts (BDs) are related to higher incidence of biliary complications (BCs) and biliary reconstruction for multiple BDs still remains…
  • 2020 American Transplant Congress

    Comparative Analysis of Risks Factors for Kidney Allograft Loss Due to Bk Nephropathy and Graft Loss Due to Other Causes: UNOS Data Set

    H. Patel1, L. Kruger1, K. Agarwal1, A. Pawar1, N. Leeaphorn2, F. Cardarelli1, N. Agrawal1

    1Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, 2Transplant Nephrology, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO

    *Purpose: 1-10% of the kidney transplant recipients develop BK virus nephropathy (BKVN). The risk factors associated with BKVN are not clearly understood. Here, we evaluate…
  • 2020 American Transplant Congress

    CCL18 Plays a Crucial Role in T Cell Recruitment in Upper Extremity Transplant Rejection

    T. J. Borges1, P. Abarzua2, B. Kollar2, M. Lima-Filho1, B. T. Aoyama1, G. F. Murphy2, B. Pomahac2, C. G. Lian2, S. G. Talbot2, L. V. Riella1

    1Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA

    *Purpose: Upper extremity transplantation (UET) is a life-changing procedure for amputee patients. However, 90% of patients experience acute skin rejection in the first post-transplant year,…
  • 2020 American Transplant Congress

    Pilot Study: Effect of Dual Ex Vivo Lung Perfusion on Human Lung Preservation

    K. Noda1, J. Sembrat2, B. J. Philips1, T. Harano1, M. Rojas2, P. G. Sanchez1, N. Shigemura3

    1Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, 2Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, 3Division of Cardiovascular Surgery, Temple University, Philadelphia, PA

    *Purpose: We have developed a novel lung preservation technique, dual ex vivo lung perfusion (dual EVLP) where both pulmonary artery (PA) and bronchial artery (BA)…
  • 2020 American Transplant Congress

    Prolonged In Vivo Perfusion of a Re-Endothelialized Human-Scale Tissue Engineered Kidney Graft

    J. S. Uzarski1, E. E. Russell1, E. C. Beck1, M. Holzner2, V. Wadhera2, D. Adamson2, T. Gilbert1, S. Florman2, D. S. Davidow1, R. Shapiro2, J. Ross1

    1Research & Development, Miromatrix Medical Inc., Eden Prairie, MN, 2Recanati/Miller Institute, Mount Sinai, New York, NY

    *Purpose: Advances are desperately needed to increase the supply of transplantable kidneys for the 100,000 patients on the waiting list. Whole organ engineering is one…
  • 2020 American Transplant Congress

    Simultaneous Robotic Kidney Transplantation and Sleeve Gastrectomy versus Transplant Alone for Morbidly Obese Patients with End-Stage Renal Failure: A Prospective Randomized Trial

    K. A. Tulla, P. West-Thielke, P. DiCocco, O. Okoye, K. Bruno, J. Almario Alvarez, M. Spaggiari, I. G. Tzvetanov, E. Benedetti

    University of Illinois at Chicago, Chicago, IL

    *Purpose: The purpose of this study is to demonstrate that simultaneous robotic assisted kidney transplant and robotic assisted sleeve gastrectomy results in fewer surgical complications…
  • 2020 American Transplant Congress

    Carfilzomib-Based Desensitization: Effects on HLA, Non-HLA, Auto, and Antiviral Antibodies

    S. Tremblay1, E. Portwood1, A. R. Shields2, R. R. Alloway1, P. A. Brailey1, E. Woodle1

    1U Cincinnati, Cincinnati, OH, 2U Cincinnati, Christ Hospital, Cincinnati, OH

    *Purpose: An important question in plasma cell (PC) therapies is the specificity of therapy for PC populations. It is known that plasmablast populations are exquisitely…
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