Am J Transplant, Volume 20, Suppl 3 Archives - Page 110 of 223 - ATC Abstracts

2020 American Transplant Congress
Development of a Transplant Financial Aid Tool Kit
C. Rogers¹, K. Minghella¹, K. Sullivan¹, J. Ryan¹, E. Keegan-Pits¹, M. Cote¹, S. Shao¹, K. Joyal¹, R. Youn², N. Elias¹
¹Massachusetts General Hospital Transplant Center, Boston, MA, ²Community, A Walgreens Pharmacy, Boston, MA
*Purpose: Medication access is an essential element to post transplant medication adherence. Access to medications can often be hindered by high copays, insurance premiums, changes…
2020 American Transplant Congress
Effect of Obesity on Short and Long Term Outcomes on Simultaneous Kidney- Pancreas Transplantation
S. Karhadkar, K. Lau, P. Singh, A. Di Carlo
Temple University School of Medicine, Philadelphia, PA
*Purpose: Pancreas transplantation has been very effective in normalizing glucose control in type 1 diabetes and more recently in type 2 diabetes with equivalent patient…
2020 American Transplant Congress
Splenectomy Impedes B Cell Infiltration Associated with Rejection of Neonatal Porcine Islet Xenografts
Z. W. Fitch, M. Song, R. Schmitz, F. Leopardi, M. Ribeiro, A. Miller, G. Devi, B. Collins, X. Luo, A. D. Kirk
Duke University, Durham, NC
*Purpose: Xenotransplantation has historically been frustrated by antibody-mediated rejection. Splenectomy has shown efficacy in mediating humoral immunity. We hypothesized that adding splenectomy to a clinically…
2020 American Transplant Congress
A Multicenter Analysis of the Proportion and Pattern of Unexplained HLA Antibodies in Kidney Recipients without a History of Sensitization
J. Lan¹, J. S. Gill¹, H. M. Gebel², R. A. Bray², R. Liwski³, A. Vinson⁴, A. Greenshields³, S. Dobrer⁵, O. Gunther⁵, K. Sherwood⁵, F. H. Claas⁶, S. Heidt⁶, G. Karahan⁶, J. Gill⁷, M. Gill¹, U. Varyani¹, P. Jindal¹, P. Keown⁵
¹Medicine, Division of Nephrology, University of British Columbia, Vancouver, BC, Canada, ²Pathology, Emory University, Atlanta, GA, ³Pathology, Dalhousie University, Halifax, NS, Canada, ⁴Nephrology, Dalhousie University, Halifax, NS, Canada, ⁵Pathology, University of British Columbia, Vancouver, BC, Canada, ⁶Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands, ⁷Nephrology, Emory University, Atlanta, GA
*Purpose: Previous studies report a high prevalence of unexplained antibody reactivities on the single antigen bead (SAB) test. In a contemporary multicenter cohort of non-sensitized…
2020 American Transplant Congress
Does Recovery Rate of Renal Plasma Flow after Kidney Transplantation Differ in the Choice of Renal Arterial Anastomotic Site?
T. Yonekura, K. Shinoda, K. Nishikawa, M. Maeda, H. Oguchi, Y. Hidaka, T. Mizutani, K. Sakurabayashi, M. Muramatsu, T. Kawamura, K. Sakai, S. Shishido
Toho University, Ota, Japan
*Purpose: Acquiring better inflow and recovery of blood supply to the renal graft is very critical in clinical kidney transplantation. Whether inflow to the renal…
2020 American Transplant Congress
Validity and Utility of Urinary CXCL10/Cr Monitoring in Pediatric Kidney Transplant Recipients
T. Blydt-Hansen¹, A. Sharma², I. Gibson², C. Weibe², A. Sharma³, V. Langlois⁴, C. Teoh⁴, D. Rush², P. Nickerson², D. Wishart⁵, J. Ho²
¹University of British Columbia, Vancouver, BC, Canada, ²University of Manitoba, Winnipeg, MB, Canada, ³University of Western Ontaria, London, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵University of Alberta, Edmonton, AB, Canada
*Purpose: Effective post-transplant monitoring is hampered by a lack of effective biomarkers. We sought to validate the utility of urinary CXCL10/Cr monitoring of rejection in…
2020 American Transplant Congress
Thalidomide and Dexamethasone Combinatorial Treatment Induces Tolerogenic Signals by Systemic Immunomodulation of T Cells and Dendritic Cells
B. Kim¹, E. Kim², J. Kim², H. Choi³, H. Lee², J. Lee⁴, M. Kim⁴, Y. Kim⁴, K. Huh⁴
¹Department of Internal Medicine, Yonsei University Health System, Seoul, Korea, Republic of, ²The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea, Republic of, ³Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of, ⁴Department of Transplantation Surgery, Yonsei University Health System, Seoul, Korea, Republic of
*Purpose: Preventing or reducing allograft rejection is critical in organ transplantation, and the need for immune modulation rather than immune suppression has been emphasized. Many…
2020 American Transplant Congress
Antibiotic Pretreatment Alleviates Liver Transplant Damage by Modulating the Composition of Commensal Microbiota
K. J. Dery, S. Kageyama, H. Hirao, K. Kadono, H. Kojima, R. W. Busuttil, J. W. Kupiec-Weglinski
Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: The human intestinal microbiome contains more than 100 trillion commensal microorganisms, exceeding the number of cells in the human body by 10-fold. Although recent…
2020 American Transplant Congress
IL-21, a Potential Target of Active Rejection in Renal Transplantation
J. Shen, R. Wang, L. Guo, J. Lv, J. Wu, J. Chen
Kidney Disease Center, First Affiliated Hospital of Zhejiang University, Hangzhou, China
*Purpose: Rejection remains an obstacle to overcome after transplantation. IL-21 is the most potent stimulators of driving GC B cells into plasma cells. Basic researches…
2020 American Transplant Congress
Impact of Liver Graft Preservation Methods on the Gut Microbiome and Metabolome
G. A. Cresci¹, N. Sangwan², A. Simioni³, Q. Liu³, C. Quintini³
¹Pediatric Gastroenterology and Inflammation & Immunity, Cleveland Clinic, Cleveland, OH, ²Lerner Research Institute, Cleveland Clinic, Cleveland, OH, ³Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Normothermic ex-vivo liver perfusion (NEVLP) is a powerful platform for organ preservation and assessment. It induces metabolic reactivation that potentially helps clear accumulated toxic…