ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Change in Hypertension (HTN) Guidelines in Living Kidney Donors (LKDs) and Long-Term Renal Outcomes

    M. Merzkani1, A. Denic1, M. D'Costa1, L. Ricaurte1, R. Narasimhan1, X. Benavides1, A. Mullan1, J. Larson1, W. Kremer1, W. Park1, M. P. Alexander1, H. Chakkera2, S. Textor1, S. Taler1, M. Stegall1, N. Issa1, A. Rule1

    1Mayo Clinic Rochester, Rochester, MN, 2Mayo Clinic Rochester, Scottsdale, AZ

    *Purpose: There is limited knowledge regarding the long-term renal outcomes in hypertensive LKDs. We performed a multicenter study assessing long-term outcomes with or without HTN…
  • 2020 American Transplant Congress

    Clinical Outcomes in Kidney Transplant Recipients Following Implementation of a Strategic Maintenance Reduction Protocol

    H. Perkins, K. Foster, N. Patel, H. Meadows, F. Bartlett, C. Perez, J. McGillicuddy, N. Pilch, M. Casey, M. A. Posadas-Salas, D. Taber

    Pharmacy, Medical University of South Carolina, Charleston, SC

    *Purpose: Post-transplant complications are commonly due to over-immunosuppression, particularly as it relates to infections. The purpose of this study was to assess clinical outcomes in…
  • 2020 American Transplant Congress

    Simultaneous Liver and Kidney Transplantation—The Lack of Influence of Pre-Formed DSA

    A. Bhansali, F. Mahir, M. Facciuto, R. Shapiro, J. Crismale, T. Schiano, G. De Boccardo

    Recanati-Miller Transplantation Institute, Mount Sinai Hospital, New York, New York, NY

    *Purpose: It is known that renal transplant recipients with preformed donor specific antibodies (DSA) have poorer outcomes associated with episodes of acute rejection (AR) and…
  • 2020 American Transplant Congress

    Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors

    A. Kernodle, M. Krach, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang

    Johns Hopkins Hospital, Baltimore, MD

    *Purpose: In a prior study using national registry data, deceased donor age greater than 50 was associated with a 35% to 61% increased risk of…
  • 2020 American Transplant Congress

    Acute Liver Failure Etiology is an Independent Predictor of Waitlist Outcome Accounting for Severity of Illness in a National Cohort

    N. Z. Wong, K. R. Reddy, T. Bittermann

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Severity of illness and liver transplant (LT) waitlist outcome can differ according to acute liver failure (ALF) etiology. However, it is unknown whether ALF…
  • 2020 American Transplant Congress

    Pharmacokinetics of Maribavir in Subjects with Moderate Hepatic Impairment

    I. H. Song1, K. Ilic2, J. Wu3

    1Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, 2Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, 3Biostat, Shire, a Takeda Company, Lexington, MA

    *Purpose: Maribavir, an investigational agent for cytomegalovirus (CMV) infection in transplant recipients, has received Breakthrough Therapy Designation. Maribavir is metabolized primarily in the liver through…
  • 2020 American Transplant Congress

    Impact and Outcomes of Primary Cytomegalovirus Infection in Seronegative Abdominal Solid Organ Transplant Recipients of Cytomegalovirus Unexposed Donors (D-/R-)

    M. Jorgenson1, M. Hillis1, N. Friedlander1, A. Gracon2, D. Yang2, G. Leverson2, J. Smith2, R. Redfield2

    1UWHC, Madison, WI, 2UWMF, Madison, WI

    *Purpose: Primary cytomegalovirus infection (CMV) in high risk (D+/R-) abdominal solid organ transplant recipients (aSOTRs) is well described, however there is a paucity of literature…
  • 2020 American Transplant Congress

    Long-Term Safety in Epstein-Barr Virus (EBV)-Seropositive Kidney-Only Transplant Recipients Treated with Belatacept (BELA) in Clinical Practice: Final Study Results from the ENLiST Registry

    C. Larsen1, F. Vincenti2, T. Kou3, C. Shadur4, B. Bresnahan5, S. Jordan6, E. S. Woodle7, N. Goes8, J. Vella9, D. Wojciechowski10, M. Polinsky3, A. Gomez-Caminero3

    1Emory University Transplant Center, Atlanta, GA, 2UCSF Transplant Center, San Francisco, CA, 3Bristol-Myers Squibb, Princeton, NJ, 4Iowa Kidney Physicians, Des Moines, IA, 5Medical College of Wisconsin, Milwaukee, WI, 6Cedars-Sinai Medical Center, Los Angeles, CA, 7University of Cincinnati, Cincinnati, OH, 8Kaiser Permanente, San Francisco, CA, 9Maine Nephrology Associates, PA, Portland, ME, 10University Hospital Kidney and Liver Transplant Clinic, Dallas, TX

    *Purpose: BELA, a selective T-cell costimulation blocker, is approved for the prophylaxis of organ rejection in EBV-seropositive adult kidney transplant recipients. In phase 3 BENEFIT…
  • 2020 American Transplant Congress

    The Role and Impact of Transplant Pharmacist Evaluation in a Pre-Kidney Transplant Clinic

    B. Valdepenas, D. Choi, J. Benken, M. Campara

    Pharmacy Practice and Transplant Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: The Centers for Medicare and Medicaid Services’ interpretative guidelines for conditions of participation for transplant centers define the transplant pharmacist’s role ambiguously. Limited evidence…
  • 2020 American Transplant Congress

    Geographical Disparities in Transplantation: Exploring the Association between County Health Rankings and an Individual’s Access to Transplantation

    A. J. Carter, R. D. Reed, D. Hendricks, K. N. Baldwin, A. C. Kale, J. E. Locke

    Surgery, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Since 2004, living kidney donation has declined, with the southeastern United States disproportionately affected. Programs such as the Living Donor Navigator (LDN), designed to…
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