Am J Transplant, Volume 20, Suppl 3 Archives - Page 102 of 223 - ATC Abstracts

2020 American Transplant Congress
Characterization of a Clinically Scaled Bioengineered Liver Seeded with Primary Hepatocytes and Endothelial Cells
D. S. Davidow¹, J. J. Ross¹, B. D. Anderson¹, A. Stumbras¹, A. A. Katane¹, R. Lindeman¹, B. G. Steiner¹, A. Mendenhall¹, K. Gahlbeck¹, S. Armstrong¹, B. P. Amiot², E. D. Nelson², T. Gilbert¹, S. L. Nyberg²
¹Miromatrix, Eden Prairie, MN, ²Mayo Clinic, Rochester, MN
*Purpose: Advancements in whole organ bioengineering have the potential to offer solutions to a chronically insufficient donor organ supply. We recently demonstrated an ability to…
2020 American Transplant Congress
Passenger Lymphocyte Syndrome Due to Anti-Rh(D) Reactivity after Kidney Transplantation: A Case Report
S. Nemr¹, S. Bani Hani¹, E. Klohe², C. Gresens³, S. Desmond¹, O. Ojogho¹
¹Kidney and Pancreas Transplant Program, Providence Sacred Heart Medical Center & Children's Hospital, Spokane, WA, ²HLA Laboratory, Inland Northwest Blood Center, Spokane, WA, ³Inland Northwest Blood Center, Spokane, WA
*Purpose: PLS can occur soon after solid organ transplantation when donor-derived antibodies against recipient red cell antigens are produced and lead to hemolysis. The anemia…
2020 American Transplant Congress
Tyrosine Receptor Kinase Axl Regulates Intragraft Trafficking of Alloreactive T Cells Post Kidney Transplantation
A. Dangi¹, K. Glinton², M. Sharma¹, S. Yu¹, M. DeBerge², E. B. Thorp², X. Luo¹
¹Nephrology/Medicine, Duke University, Durham, NC, ²Pathology, Northwestern University, Chicago, IL
*Purpose: Previous studies have shown that receptor tyrosine kinase Axl, primarily expressed on dendritic cells and some tissue-specific macrophage population, is required for T cells…
2020 American Transplant Congress
Undernutrition and Hypoleptinemia Modulate Cytomegalovirus Infection
E. David¹, M. Zhu², W. Parker², N. MacIver¹, A. D. Kirk², E. T. Chambers¹
¹Pediatrics, Duke University, Durham, NC, ²Surgery, Duke University, Durham, NC
*Purpose: Cytomegalovirus (CMV) viremia/infection remains a significant cause of morbidity in transplantation, especially in the undernourished population. Undernutrition and hypoleptinemia have been implicated in other…
2020 American Transplant Congress
Treg Lymphotoxin Signals Promote Cancer Metastatic Migration: Mechanisms for Treg-Cancer Interaction
W. Piao¹, R. Oakes², C. Paluskievicz¹, Y. Xiong¹, L. Li¹, V. Saxena¹, M. WillsonShirkey¹, C. Jewell², J. Bromberg¹
¹Surgery, U of Maryland, Baltimore, MD, ²U of Maryland, College Park, MD
*Purpose: Immune suppressive therapy can be complicated by malignancy. Regulatory T cells (Treg) control immune tolerance for graft survival but cause to immune suppression in…
2020 American Transplant Congress
Clinical Outcomes Associated with Long-Term Exposure to Airborne Particulate Pollution in Kidney Transplant Recipients
Y. Kim¹, J. Lee²
¹Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ²Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of
*Purpose: We aimed to evaluate the relationship of 10-μm particulate matter (PM10) with the risk of graft failure, mortality, and decline of graft function in…
2020 American Transplant Congress
Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates
A. Kardashian¹, J. Ge¹, C. McCulloch¹, M. R. Kappus², M. A. Dunn³, A. Duarte-Rojo³, M. L. Volk⁴, R. S. Rahimi⁵, E. C. Verna⁶, D. R. Ganger⁷, D. Ladner⁷, J. L. Dodge¹, B. Boyarsky⁸, M. McAdams-DeMarco⁸, D. L. Segev⁸, J. C. Lai¹
¹UCSF, SF, CA, ²Duke, Durham, NC, ³UPMC, Pittsburgh, PA, ⁴LLU, Loma Linda, CA, ⁵BSWH, Dallas, TX, ⁶Columbia, NY, NY, ⁷Northwestern, Chicago, IL, ⁸JHMI, Baltimore, MD
*Purpose: Frailty is associated with mortality in liver transplant (LT) waitlist candidates. We developed the Liver Frailty Index (LFI) to assess frailty in patients with…
2020 American Transplant Congress
Improving DRG Based Reimbursement to Reflect Complexity of Kidney Transplant
I. R. Schwantes¹, M. Schnitzler², K. Lentine², A. Reed¹, D. A. Axelrod³
¹Surgery, University of Iowa, Iowa City, IA, ²Saint Louis University, St. Louis, MO, ³Surgery, Universtiy of Iowa, Iowa City, IA
*Purpose: More than 90,000 individuals await a kidney transplant (KTx) in the US, yet up to 20% of recovered kidneys are discarded. Organ Transplant Centers…
2020 American Transplant Congress
Intimal Arteritis in Association with Microvascular Inflammation Leads to Inferior Graft Survival Regardless DSA
M. Novotny¹, E. Honsova², O. Viklicky¹
¹Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Intimal arteritis belongs between diagnostic criteria of both antibody-mediated rejection (AMR) and T cell-mediated vascular rejection (TCMRV). Patients with intimal arteritis must be assessed…
2020 American Transplant Congress
Application of Image-Guidance Using 2D Illustrations and 3D Modeling of Donor Anatomy During Living Donor Hepatectomy
M. Lim, S. Kim, K. Kim, O. Lee, J. Kwon, E. Jeong, J. Yang, G. Choi
Transplantation, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: For living donor liver transplantation, preoperative imaging is required for the safety of donor and recipient. As we started our image-guidance program using 2D…