Am J Transplant, Volume 20, Suppl 3 Archives - Page 101 of 223 - ATC Abstracts

2020 American Transplant Congress
TGR5/Cathepsin E Signaling Regulates Macrophage Innate Immune Activation in the Sterile Inflammatory Liver Injury
H. Zhou, S. Zhou, Q. Wang, Z. Rao, X. Wang, L. Lu
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: The hepatic proinflammatory response represents a major cause of liver ischemia and reperfusion (IR) injury. Although the role of plasma membrane-bound G protein-coupled bile…
2020 American Transplant Congress
Withaferin A Prolongs Islet Allograft Survival in a Mouse Transplant Model by Preventing T Lymphocyte Proliferation and Dendritic Cell Maturation
K. Kumano¹, M. A. Kanak², S. Vasu¹, Y. Liu¹, M. Lawrence¹, B. Naziruddin¹
¹Baylor University Medical Ctr, Dallas, TX, ²Virginial Commonwealth University Medical Center, Richmond, VA
*Purpose: Chronic decline in islet graft function and toxicities imposed by immunosuppressant drugs remain as challenges to the widespread use of islet transplantation for type…
2020 American Transplant Congress
Next Generation Sequencing Based Analysis of the T-Cell Receptor Repertoire Reveals an Increase of Alloreactive T-Cell Clones after Kidney Transplantation
C. Aschauer¹, K. Jelencsics¹, K. Hu¹, R. Reindl-Schwaighofer¹, J. Vetter², A. Heinzel¹, A. Kainz¹, G. Gualdoni¹, S. Schaller², S. Winkler², R. Oberbauer¹
¹Department of Medicine III - Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria, ²Bioinformatics Research Group, University of Applied Sciences Upper Austria, Hagenberg im Muehlkreis, Austria
*Purpose: The development of the alloreactive T-cell repertoire after kidney transplantation (KTX) is not yet fully understood. The combination of mixed lymphocyte reaction (MLR) and…
2020 American Transplant Congress
Comparing Early Kidney after Liver Transplant (KALT) and Simultaneous Liver-Kidney Transplant (SLK): Evaluating Racial Disparities. Will Everyone Have the Same “Safety Net”?
C. Jay¹, R. Stratta¹, W. Washburn², J. Rogers¹, S. Rudnick¹, A. Reeves-Daniel¹, J. Heimbach³
¹Wake Forest Baptist Health, Winston-Salem, NC, ²The Ohio State University Wexner Medical Center, Columbus, OH, ³Wake Forest Baptist Health, Winston-Salem, MN
*Purpose: In 2017, UNOS implemented simultaneous liver-kidney transplant (SLK) guidelines that included medical eligibility criteria and a “safety net” providing prioritization on the kidney transplant…
2020 American Transplant Congress
Does the Distance from the Transplant Center Impact Kidney Transplant (KT) DGF, CIT and Outcomes?
M. Laftavi¹, O. Pankewycz², R. Shahbazov¹, A. Almonte¹, B. Gallay², J. Leggat², R. Hod Dvorai¹, C. Hubbell¹, S. Narsipur²
¹Transplant, Upstate Medical University, SYRACUSE, NY, ²Nephrology, Upstate Medical University, SYRACUSE, NY
*Purpose: Currently, there is an ongoing debate regarding the efficient use of available organs (utility) versus the fair access to transplant (equity). UNOS is now…
2020 American Transplant Congress
Impact of Kidney Donor Profile Index (KDPI) on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury
A. Brar¹, M. Salifu², D. Adey¹, A. Gruessner²
¹University of California, San Francisco, San Francisco, CA, ²SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Kidneys with donor acute kidney injury (AKI) are discarded at a higher rate. The purpose of the study is to assess long term renal…
2020 American Transplant Congress
Impact of Immunosuppression Protocol on the Incidence of EBV Viremia and PTLD in Pediatric Kidney Transplant Recipients: A Single Center Experience
K. Bowers¹, V. M. Panzarino¹, A. Campos¹, J. Buggs², V. D. Bowers²
¹Pediatrics, USF, Tampa, FL, ²Transplant Surgery, TGH, Tampa, FL
*Purpose: The purpose of this study was to evaluate the efficacy of an immunosuppression protocol change, which included avoidance of anti-thymocyte globulin for induction and…
2020 American Transplant Congress
Living Kidney Donor Assessment: Kidney Length versus Differential Function
K. J. Schumacher, J. A. Akoh
General and Transplant Surgery, Plymouth University Hospitals NHS Trust, Plymouth, United Kingdom
*Purpose: The key question in living kidney donor assessment is how best to determine the contribution of each kidney to overall renal function as a…
2020 American Transplant Congress
The Long Term Impact of Metabolic Syndrome on Post-Donation in Living Kidney Donors
C. Chen, T. Yu, Y. Chuang, S. Tsai, M. Wu
Division of Nephrology, Taichung Veterans General Hospital, Taichung, Taiwan
*Purpose: The long waiting list for kidney transplant (KTx) in Taiwan, the willingness of transplant centers increase to accept complex donors, eg. metabolic syndrome (MS).…
2020 American Transplant Congress
Validation of Patient Reported Outcomes Measurement Information System (PROMIS) Computer Adaptive Testing Depression Item Bank in Kidney Transplant Recipients
V. Shah¹, A. Rezaeishahreza¹, E. Lui¹, R. Aser¹, S. Bartlett², M. Li¹, D. Howell¹, J. Peipert³, M. Novak¹, I. Mucsi¹
¹University Health Network, Toronto, ON, Canada, ²McGill University, Montreal, QC, Canada, ³Northwestern University, Chicago, IL
*Purpose: To evaluate the reliability and validity of the PROMIS Depression computerized adaptive test (PROMIS-D CAT) in relation to a legacy measure in adult Kidney…