ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Multidisciplinary Practitioner Perspectives on Cardiovascular Disease Guideline Interventions in Liver Transplant Recipients

    M. Kosirog1, L. Adamski1, A. Daud2, D. Finn2, D. Gregory1, D. M. Lloyd-Jones3, J. L. Holl4, L. B. VanWagner5

    1Medicine-GI & Hepatology, Northwestern University, Chicago, IL, 2Center for Healthcare Studies, Northwestern University, Chicago, IL, 3Medicine-Cardiology and Preventive Medicine, Northwestern University, Chicago, IL, 4Pediatrics & Center for Healthcare Studies, Northwestern University, Chicago, IL, 5Medicine-GI & Hepatology and Preventive Medicine, Northwestern University, Chicago, IL

    *Purpose: Cardiovascular disease (CVD) is a leading cause of mortality in liver transplant recipients (LTRs). However, there is a lack of LT-specific CVD clinical practice…
  • 2019 American Transplant Congress

    Totally Robotic Donor Hepatectomy: Feasibility And Early Outcomes

    Y. Cheah, C. J. Simon, W. D. Lewis, R. L. Jenkins, M. E. Akoad

    Lahey Hospital & Medical Center, Burlington, MA

    *Purpose: Robotic surgery is emerging as a surgical technique to enable resection of the liver using minimally invasive techniques; however, very few living donor liver…
  • 2019 American Transplant Congress

    Activation of Renal Fibroblasts by Anti- Major Histocompatibility Complex Antibody: A Missing Link in Allograft Fibrosis

    M. B. Oliver1, J. Chen2, A. Zmijewska1, R. B. Mannon1

    1Medicine, Division of Nephrology, The University of Alabama at Birmingham, Birmingham, AL, 2Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, The University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Chronic antibody-mediated rejection (CAMR) is an important contributor to late kidney allograft loss, frequently accompanied by interstitial fibrosis and tubular atrophy. Donor-specific antibodies (DSA)…
  • 2019 American Transplant Congress

    Bortezomib Attenuates the Progression of Epithelial to Mesenchymal Transition through Smurf1 Akt mTOR P70S6K Pathway in Rat Allograft Renal Interstitial Fibrosis Model

    R. Tan, Z. Wang, S. Fei, Z. Han, J. Tao, X. Ju, M. Gu

    No.300 Guangzhou Road of Nanjing, Nanjing, China

    *Purpose: Our study was to detect the effects of Bortezomib and Smurf1 in the EMT and allograft renal interstitial fibrosis.*Methods: Biomarkers of EMT, as well…
  • 2019 American Transplant Congress

    Deficiency of IRE1a Ameliorates Renal Allograft Injury via Remodeling of Graft-Infiltrating Macrophages

    L. Qiu1, J. Wang1, X. Yeap1, S. Han1, F. Zheng1, D. Fang2, Z. J. Zhang1

    1Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL, 2Department of Pathology, Northwestern University, Chicago, IL

    *Purpose: Inflammatory macrophages contribute to the development of ischemia-reperfusion injury (IRI) and allograft rejection. However, the underlying mechanisms by which macrophage mediate allograft injury and…
  • 2019 American Transplant Congress

    Comparison of Oral Microbiome in Stable vs Declining Kidney Function in Renal Transplant Recipients

    J. Wu1, A. Muthusamy2, G. Al-Ghalith3, B. Wu4, B. Guo4, W. Guan4, D. Knights3, W. Oetting5, D. Schladt2, R. Remmel5, P. Jacobson5, A. K. Sharma6, A. Matas7, A. Israni1, D. Skaar8

    1Nephrology, Hennepin Healthcare, Minneapolis, MN, 2Hennepin Health Research Institute, Minneapolis, MN, 3Computer Science, University of Minnesota, Minneapolis, MN, 4Biostatistics, University of Minnesota, Minneapolis, MN, 5Pharmacy, University of Minnesota, Minneapolis, MN, 6Animal Science, University of Minnesota, Minneapolis, MN, 7Surgery, University of Minnesota, Minneapolis, MN, 8Denistry, University of Minnesota, Minneapolis, MN

    *Purpose: Transplantation causes dysbiosis of the oral microbiome of renal transplant recipients and has been correlated with worse allograft outcomes. We hypothesize that there are…
  • 2019 American Transplant Congress

    Mesangiopathic Glomerulonephritis in Kidney Transplants

    G. Towns, G. Agarwal, S. Ong, R. Mundra, C. Kew

    UAB, Birmingham, AL

    *Purpose: Describe higher than anticipated prevalence of Mesangiopathic Glomerulonephritis on surveillance biopsies.*Methods: Review of all surveillance biopsies from September 2014 through September 2018 for presence…
  • 2019 American Transplant Congress

    The Interaction between Post-Transplant Anemia and Allograft Function in Kidney Transplantation

    Y. Kakuta1, M. Okumi1, T. Kanzawa1, K. Unagami2, H. Ishida2, K. Tanabe1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan, 2Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: Post-transplant anemia (PTA) is one of the common complications, which was observed in about 30% to 40% of kidney transplant recipients. The interaction effect…
  • 2019 American Transplant Congress

    Comparison of Planned vs. Unplanned Pregnancies in Female Kidney Transplant Recipients

    S. Rao1, L. A. Coscia2, D. Kliniewski2, S. Constantinescu3, M. J. Moritz4

    1Medicine, University of Virginia Health System, Charlottesville, VA, 2Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA, 3Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 4Surgery, Lehigh Valley Health Network, Allentown, PA

    *Purpose: The purpose of this study is to analyze the impact of planned vs. unplanned pregnancies in 897 female kidney transplant recipients.*Methods: Data were collected…
  • 2019 American Transplant Congress

    Attitude towards Organ Donation among Medical Students: Relationship to Knowledge and Beliefs

    A. Cerrato, M. Salifu, M. Markell

    Nephrology/Medicine, SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Lack of knowledge or misunderstanding of organ donation may underlie physician unwillingness to refer patients for organ donation. We examined baseline knowledge and beliefs…
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