Comparison of Planned vs. Unplanned Pregnancies in Female Kidney Transplant Recipients
1Medicine, University of Virginia Health System, Charlottesville, VA, 2Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA, 3Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 4Surgery, Lehigh Valley Health Network, Allentown, PA
Meeting: 2019 American Transplant Congress
Abstract number: C100
Keywords: High-risk, Kidney transplantation, Pregnancy, Quality of life
Session Information
Date: Monday, June 3, 2019
Session Name: Poster Session C: Kidney Psychosocial
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall C & D
*Purpose: The purpose of this study is to analyze the impact of planned vs. unplanned pregnancies in 897 female kidney transplant recipients.
*Methods: Data were collected by the Transplant Pregnancy Registry International (TPR), a voluntary pregnancy registry using questionnaires, telephone interviews, and medical records review. Maternal, fetal, and transplant outcomes were compared between women who self-reported planned versus unplanned pregnancies.
*Results: Shown in Table 1 are the results of the analyses.
Recipients reporting an unplanned pregnancy were: significantly younger at the time of transplant and conception, had shorter transplant to conception intervals, were more likely to be taking mycophenolic acid products during pregnancy, and had higher rates of hypertension, rejection both during and after pregnancy, and graft loss within 2 years of pregnancy. Newborn outcomes were similar between planned and unplanned pregnancies.
*Conclusions: Overall, pregnancy outcomes were similar when comparing planned and unplanned pregnancies. However, maternal and transplant outcomes were significantly worse for those with an unplanned pregnancy, with more rejection and greater risk of graft loss within 2 years of pregnancy. Contraception and pre-pregnancy counseling for kidney transplant recipients is imperative to attempt to reduce the number of unplanned pregnancies in kidney transplant recipients.
To cite this abstract in AMA style:
Rao S, Coscia LA, Kliniewski D, Constantinescu S, Moritz MJ. Comparison of Planned vs. Unplanned Pregnancies in Female Kidney Transplant Recipients [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/comparison-of-planned-vs-unplanned-pregnancies-in-female-kidney-transplant-recipients/. Accessed March 7, 2021.« Back to 2019 American Transplant Congress