ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Donor Lymphocyte Chimerism and Homozygosity Are Critical Indicators for Timely and Accurate Diagnosis of Acute Graft vs. Host Disease after Liver Transplantation

    A. Zhang, B. Eghtesad

    Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: The mortality of Acute Graft vs. Host Disease (aGvHD) after Liver Transplantation (LT) can be greater than 85% due to delays in diagnosis and…
  • 2019 American Transplant Congress

    Thymoglobulin Induction with Tacrolimus and Everolimus Maintenance Therapy in Elderly Kidney Transplantation Results in Prolonged Lymphocyte Depletion and Do Not Favor Regulatory Profile

    E. David-Neto1, G. Ramos de Freitas1, M. Fernandes1, F. Agena1, F. Brambate Carvalhinho Lemos1, F. Jota de Paula1, V. Coelho2, N. Zocoler Galante1

    1Renal Transplantation Service, Hospital das Clínicas - University of São Paulo School of Medicine, Sao Paulo, Brazil, 2Laboratory of Immunology – LIM 19, Heart Institute - University of São Paulo School of Medicine, Sao Paulo, Brazil

    *Purpose: Despite the growing number of elderly kidney transplant (Ktx) recipientes few studies describe the effects of immunosuppression on this group. We evaluated the immunological…
  • 2019 American Transplant Congress

    S1PR1 and S1PR4 Regulate T Cell Migration into Afferent Lymphatics

    Y. Xiong1, W. Piao1, C. Brinkman1, L. Li1, J. Kulinski2, A. Olivera2, A. Cartier3, T. Hla4, K. Hippen5, B. Blazar6, S. Schwab7, J. Bromberg1

    1Surgery, UMB, Baltimore, MD, 2NIH, Bethesda, MD, 3Boston Children's hospital, Boston, MA, 4Boston Children's, Boston, MA, 5U.Minnesota, Minneapolis, MN, 6U.Minnesota, Minneapolis, MD, 7NYU, NY, NY

    *Purpose: T cells utilize S1PR1 to traffic from thymus into blood, and lymph nodes (LN) into efferent lymphatics. Whether T cell S1PR1 and S1PR4 regulate…
  • 2019 American Transplant Congress

    Opioid Use Policies and Practices in Liver Transplant and Lung Transplant Candidates: A Comparison of National Surveys

    H. Bruschwein1, V. Andersen1, H. Patel2, S. S. Rogal3, J. N. Fleming4

    1University of Virginia, Charlottesville, VA, 2University of North Carolina, Chapel Hill, NC, 3University of Pittsburgh, Pittsburgh, PA, 4Medical University of South Carolina, Charleston, SC

    *Purpose: Pre-transplant opioid use has been associated with increased risk of morbidity and mortality. Alternatively, opioid substitution therapy (OST) has been proven to be a…
  • 2019 American Transplant Congress

    Limited Accessibility of Kidney Transplantation in Rural Residents: A Nationwide Data of South Korea

    J. Kim1, K. Park1, S. Park1, M. Yu2, Y. Kim1, J. Jeong1, K. Kim1, M. Park3, H. Lee1

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Hanyang University Guri Hospital, Gyeonggi-do, Korea, Republic of, 3Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: Kidney transplantation (KT) is the best modality of renal replacement therapy (RRT) for patients with end-stage renal disease (ESRD). It is suggested that KT…
  • 2019 American Transplant Congress

    The Reduced Tacrolimus Metabolism Rate and Its Association with Estimated Glomerular Filtration Rate and Interstitial Fibrosis: A Study Using Korean Organ Transplantation Registry (KOTRY) Dataset

    J. Jeong1, H. Ro2, T. Koo3, J. Yang3, M. Kim4, S. Shin5, J. Park6, T. Ban7, S. Han8, T. Kim9, C. Ahn10

    1Ajou University School of Medicine, Suwon, Korea, Republic of, 2Gachon University, Incheon, Korea, Republic of, 3Seoul National University Hospital, Seoul, Korea, Republic of, 4Yonsei University College of Medicine, Seoul, Korea, Republic of, 5Asan Medical Center, Seoul, Korea, Republic of, 6Samsung Medical Center, Seoul, Korea, Republic of, 7Seoul St Mary's Hospital, Seoul, Korea, Republic of, 8Keimyung University School of Medicine, Daegu, Korea, Republic of, 9Inje University, Busan Paik Hospital, Busan, Korea, Republic of, 10Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Tacrolimus is the key drug in clinical transplant, which has narrow therapeutic index. A few studies reported the association of tacrolimus metabolism rate with…
  • 2019 American Transplant Congress

    Unfavorable Donor after Cardiac Death Characteristics in Lung Transplantation: An Analysis of the UNOS Registry

    A. Y. Choi1, O. K. Jawitz2, V. Raman2, Y. Barac2, M. S. Mulvihill2, C. Moore2, M. G. Hartwig2

    1Duke University School of Medicine, Durham, NC, 2Department of Surgery, Duke University Medical Center, Durham, NC

    *Purpose: Despite growing evidence that donation after circulatory death (DCD) lung transplants have comparable survival outcomes and primary graft dysfunction rates to donation after brain…
  • 2019 American Transplant Congress

    REHANNA: Renal Transplants in Hepatitis C Negative Recipients with Nucleic Acid Positive Donors with Short Course Direct Acting Antiviral Prophylaxis

    C. Durand, B. Barnaba, D. Brown, N. Bair, F. Naqvi, M. Bowring, D. Segev, M. Sulkowski, N. Desai

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: To mitigate the current organ shortage and underutilization of hepatitis C-infected deceased donor (HCV D+) organs, we evaluated the use of HCV D+ kidneys…
  • 2019 American Transplant Congress

    Apparatus and Method to Facilitate In-Situ Cold Perfusion of Abdominal Organs in DCD Donors

    M. Jendrisak

    Gift of Hope Organ & Tissue Donor Network, Itasca, IL

    *Purpose: Rapid, effective in-situ cold perfusion of the abdominal organs in the setting of donation after circulatory death (DCD) is a critical surgical task to…
  • 2019 American Transplant Congress

    What Are Factors That Can Influence The High Immunological Graft Loss Rate In Young Pancreas Transplant Recipients

    A. C. Gruessner, J. Renz, S. Saggi, R. W. Gruessner

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Pancreas transplants (tx) are increasingly performed in older patients with type 1 diabetes mellitus. This trend may be explained by the significantly higher immunologic…
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