Am J Transplant, Volume 19, Suppl 3 Archives - Page 54 of 214 - ATC Abstracts

2019 American Transplant Congress
The Incidence of Fungal Infections in Pancreas Transplant Recipients in the Absence of Systemic Antifungal Prophylaxis
S. Shaikh¹, M. Cooper¹, A. Nolan¹, P. Abrams²
¹MedStar Georgetown University Hospital, Washington, DC, ²MedStar Gerogetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC
*Purpose: Fungal infections after pancreas transplantation have been associated with morbidity and mortality, therefore transplant centers may elect to use systemic perioperative antifungal prophylaxis (ppx).…
2019 American Transplant Congress
Can Cxcl8 Inhibitor (reparixin) Improve Islet Engraftment And Clinical Outcomes After Islet Allotransplantation? University Of Chicago Preliminary Results From A Phase 3 Multicenter Randomized, Double-blinded, Prospective Study.
P. Bachul¹, K. Golab¹, L. Basto¹, L. Wang¹, M. Tibudan¹, J. Golebiewska², M. Para¹, L. Perea¹, F. Antic¹, J. Fung¹, P. Witkowski¹
¹University of Chicago Medicine, Chicago, IL, ²Medical University of Gdansk, Gdansk, Poland
*Purpose: Reparixin is a novel CxCR1/2 chemokine receptor-blocking molecule, which has been shown improving islet engraftment in animal models. A multicenter trial was organized to…
2019 American Transplant Congress
Parental Anxiety and Depression Rates across Pediatric Solid Organ Transplant Populations
A. M. Lofton¹, A. Wille¹, E. A. Steinberg², C. Buchanan²
¹Psychiatry, Children's Hospital Colorado, Aurora, CO, ²Psychiatry, University of Colorado SOM, Children's Hospital Colorado, Aurora, CO
*Purpose: This study’s purpose is to examine parental self-report of depression and anxiety symptoms during the pre-transplant evaluation process for solid organ transplant pediatric candidates…
2019 American Transplant Congress
Post-Transplant Cancer Following Living Donor HLA-Incompatible Kidney Transplantation
J. D. Motter¹, K. Jackson¹, S. Bae¹, X. Luo¹, J. Long¹, L. Kucirka¹, B. Orandi², A. Muzaale¹, J. Coresh¹, J. Garonzik-Wang¹, D. Segev¹, A. Massie¹
¹Johns Hopkins University, Baltimore, MD, ²University of Alabama, Birmingham, AL
*Purpose: Incompatible living donor kidney transplantation (ILDKT) recipients require increased immunosuppression compared to their compatible living donor kidney transplant (CLDKT) counterparts. This continued exposure to…
2019 American Transplant Congress
Retrospective Nested Case Control Study of the Impact of Immunosuppression on Post Transplant Malignancy among Adult Heart Transplant Patients
S. Crow, R. J. Bubik, S. S. Kushwaha, K. C. Mara, R. A. Dierkhising, N. L. Pereira
Mayo Clinic, Rochester, MN
*Purpose: Post-transplant malignancy is diagnosed in approximately 18% of heart transplant (HTx) recipients and is a leading long-term cause of death among these patients. The…
2019 American Transplant Congress
Transplantation of Hepatitis C Virus Positive Donor Kidneys into Hepatitis C Negative Older Recipients
J. A. Graham¹, M. Ajaimy², J. Torabi¹, T. Powell³, J. Weiss⁴, T. Weinstein⁵, S. Greenstein¹, O. Andacoglu¹, A. Campbell⁶, J. Carrero¹, J. Lapponese¹, M. Kinkhabwala¹, E. Akalin², J. P. Rocca¹
¹Surgery, Montefiore Medical Center, Bronx, NY, ²Medicine, Montefiore Medical Center, Bronx, NY, ³Epidemiology and Psychiatry, Montefiore Medical Center, Bronx, NY, ⁴Medical Affairs, Montefiore Medical Center, Bronx, NY, ⁵Risk & Loss Prevention, Montefiore Medical Center, Bronx, NY, ⁶Pharmacy, Montefiore Medical Center, Bronx, NY
*Purpose: Patients awaiting transplantation are often at risk of developing life-threatening disease and complications. Older patients have a disproportionately higher risk of dropping out of…
2019 American Transplant Congress
Blood Profiling Reflects a Significant Down-Regulation in Oxidative Phosphorylation Following Renal Transplantation with DCD and AKI Allografts
S. Walker¹, L. Cox², C. Langefeld², B. Freedman², A. Farney², J. Rogers², C. Jay², R. Stratta², G. Orlando²
¹Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, ²Wake Forest Baptist Medical Center, Winston Salem, NC
*Purpose: The human kidney transplant (KT) patient provides a unique and compelling in situ model system to study molecular events that underlie graft recovery following…
2019 American Transplant Congress
Perioperative Blood Transfusion Significantly Increases Inpatient Morbidity and Mortality in Renal Transplant Recipients: 15-year Experience
K. Mahendraraj¹, G. Medrano del Rosal¹, M. Kruse¹, R. Shah¹, T. Katsichtis¹, T. Brennan², N. Nissen², T. Todo², K. Kosari², A. Klein², I. Kim²
¹Surgery, Lincoln Medical Center, New York, NY, ²Transplant Surgery, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: This study evaluates the immediate effects of perioperative blood transfusion (PBT) on inpatient morbidity and mortality among renal transplant (RT) recipients during their index…
2019 American Transplant Congress
Barriers to Pre-Transplant Immunization: A Qualitative Study of Pediatric Liver-Transplant Stakeholders
A. G. Feldman¹, R. Marsh², A. Kempe³, M. Morris²
¹Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, ²University of Colorado, Aurora, CO, ³Pediatrics, University of Colorado, Aurora, CO
*Purpose: Less than 30% of pediatric liver transplant recipients are up-to-date on age-appropriate immunizations at the time of transplant despite being at high-risk for infections…
2019 American Transplant Congress
Ablation of Interferon Regulatory Factor 4 in T Cells Induces “Memory” of Transplant Tolerance That is Irreversible by Immune Checkpoint Blockade
H. Zhang¹, J. Wu², D. Zou³, W. Chen³
¹The second Xiangya Hospital, Changsha, China, ²Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ³Immunobiology & Transplant Science Center, Houston Methodist Research Institute, Houston, TX
*Purpose: Achieving alloantigen-specific transplant tolerance through ablation of interferon regulatory factor 4 in T cells*Methods: 1. Irf4fl/flCD4-Cre recipients were first transplanted with BALB/c hearts and…