ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Laminin α5 Deficiency in Lymph Node Stromal Cells Promotes Treg Migration and Allograft Survival

    L. Li, M. Shirkey, W. Piao, Y. Xiong, V. Saxena, T. Zhang, T. Simon, N. Toney, C. Paluskievicz, J. S. Bromberg

    Surgery, U. Maryland, Baltimore, Baltimore, MD

    *Purpose: Laminins are a family of heterotrimeric glycoproteins, and lymph node (LN) stromal laminins α4 and α5 modulate suppression and immunity, respectively. We created laminin…
  • 2019 American Transplant Congress

    No Gains In Long-term Survival Of Pediatric Patients After Liver Transplantation – A Three Decade Analysis

    S. Bakhtiyar, A. Rana, S. Ahmed, H. Naseem, M. Kueht, N. T. Galvan, R. T. Cotton, C. A. O'Mahony, J. A. Goss

    Baylor College of Medicine, Houston, TX

    *Purpose: The aim of this study was to assess improvements in long-term survival of pediatric patients after liver transplantation, by analyzing outcomes in transplant recipients…
  • 2019 American Transplant Congress

    Transplant Nephrologist

    K. A. AlMeshari1, D. Broering2, I. Alahmadi3, S. Raza3, T. Ali3, F. Alzayer4, A. Algharabli4

    1King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 2Organ Transplant Center, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 3Kidney & Pancreas Transplantation Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, 4Department of Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia

    *Purpose: Matching rates of very highly sensitized patients with cPRA of 91 - 100% (VHSP) and blood type O recipients of ABO incompatible donors (ABO…
  • 2019 American Transplant Congress

    Impact of Once-Daily Tacrolimus on Trough Concentration Variability in Stable Adolescent and Young Adult Renal Transplant Recipients

    M. Moss, J. Goebel, A. Lofton, E. Steinberg, M. Bock

    Children's Hospital Colorado, Aurora, CO

    *Purpose: High tacrolimus concentration variability (Vtac), likely influenced by medication non-adherence, is a risk factor for graft dysfunction and loss among renal transplant recipients (RTRs),…
  • 2019 American Transplant Congress

    Care of International Living Kidney Donor Candidates in the U.S.: A Survey of Contemporary Experience, Practice & Challenges

    K. Lentine1, M. Henderson2, S. Rasmussen2, E. Shukhman3, J. Hunt4, F. Al Ammary2, V. Kumar5, D. Lapointe-Rudow4, H. Schaefer6, M. Cooper7, R. Hays8, M. Dunbar-Forrest9, A. Nishio-Lucar10, D. Mandelbrot8

    1Saint Louis Univ, Saint Louis, MO, 2Johns Hopkins, Baltimore, MD, 3Cedars Sinai, Los Angeles, CA, 4Mount Sinai, New York, NY, 5Univ Alabama, Birmingham, AL, 6Vanderbilt, Nashville, TN, 7Georgetown, Washington, DC, 8Univ Wisconsin, Madison, WI, 9UCLA, Los Angeles, CA, 10Univ Virginia, Charlottesville, VA

    *Purpose: The evaluation and care of non-U.S. citizen, non-U.S. residents who wish to come to the U.S. to serve as living kidney donors (LKD) can…
  • 2019 American Transplant Congress

    Association Of Lymphocyte-depleting Antibody And Steroids Induction With The Risk And Outcomes Of Post-transplant Diabetes: Analysis Of Deceased-donor Kidney Transplants

    A. Santos1, J. Gregg2, U. L. Akanit3, K. Alquadan1, H. Bejjanki1, K. L. Womer1

    1Div. of Nephrology, Hypertension & Renal Transplantation, University of Florida, Gainesville, FL, 2University of Florida, Gainesville, FL, 3Ubon Ratchathani University, Ubonratchathani, Thailand

    *Purpose: We aimed to determine the risk and outcomes of post-transplant diabetes(PTDM) associated with combined lymphocyte-depleting antibody (LDA) [anti-thymocyte globulin (ATG) or alemtuzumab (ALM)] and…
  • 2019 American Transplant Congress

    Memory T Follicular Helper Cell Alloresponse is Memory B Cell Independent and Inhibited by CD28 Costimulation Blockade

    S. Zeng, G. M. La Muraglia II, M. L. Ford, I. R. Badell

    Emory University School of Medicine, Atlanta, GA

    *Purpose: Donor-directed HLA antibodies are an important cause of renal allograft injury, but reliable and durable therapeutic options to prevent or eliminate donor-specific antibodies (DSA)…
  • 2019 American Transplant Congress

    Human Urine-Derived Stem Cells Protect against Renal Ischemia Reperfusion Injury via Releasing Exosomal miR-146a-5p Which Targets IRAK1 in a Rat Model

    X. Li, Z. Bi, Q. Su, H. Huang, L. Liu, C. Wang

    Organ Transplant Center, Sun Yat-sen University, Guangzhou, China

    *Purpose: Severe ischemia reperfusion injury (IRI) causes delayed graft function and impaires renal allograft survival. Human urine-derived stem cells (hUSCs) is a new source of…
  • 2019 American Transplant Congress

    Improving Living Donor Follow Up

    L. Aronoff, V. Nair, C. Flores, M. Bhaskaran, E. Molmenti, A. Fahmy, M. Zhou, E. Grodstein, D. Campbell, C. Literello, L. Teperman

    Renal Transplant, Northwell Health, Manhasset, NY

    *Purpose: OPTN requires transplant centers follow living donors (LDs) at 6 months, 1 year and 2 years post donation with a minimum threshold of 95%…
  • 2019 American Transplant Congress

    After 10 Years: The Results of HLA Mismatched Combined Kidney and Bone Marrow Transplantation for Renal Allograft Tolerance

    T. Kawai1, D. H. Sachs1, T. Spitzer1, N. Tolkoff-Rubin1, R. B. Colvin1, N. Elias1, M. Sykes2, A. Cosimi1

    1Massachusetts General Hospital, Boston, MA, 2Columbia University, NYC, NY

    *Purpose: Based on decades-long basic studies in animal models, we have applied combined kidney and donor bone marrow transplantation (CKBMT) for induction of allograft tolerance…
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