ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Platelets Stimulate Liver Regeneration in a 30% Partial Liver Transplantation Model in Rat

    C. Liang, K. Takahashi, T. Oda, N. Ohkohchi

    University of Tsukuba, Tsukuba, Japan

    *Purpose: Thirty years after the first living donor liver transplantation (LDLT), this technique has been widely recognized as the golden standard in treatment of end-stage…
  • 2019 American Transplant Congress

    Effects of Pretreated Bortezomib on Renal Function after Renal Ischemia – Reperfusion Injury in Mice

    X. Zheng

    Beijing Chaoyang Hospital, Capital Medical University, Beijing, China

    *Purpose: To observe the effects of pretreated bortezomib at different points on renal function and renal histology after renal ischemia-reperfusion injury in mice.*Methods: A mice…
  • 2019 American Transplant Congress

    Immunization Status at the Time of Pediatric Liver Transplant: A 1-year Study through The Society of Pediatric Liver Transplantation

    A. G. Feldman1, A. Kempe2, B. L. Beaty3, R. Torres1, D. Curtis4, S. S. Sundaram1

    1Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, 2Pediatrics, University of Colorado, Aurora, CO, 3University of Colorado, Aurora, CO, 4Pediatric Infectious Diseases, University of Colorado, Aurora, CO

    *Purpose: Vaccine preventable infections are a serious and common complication following transplant. Immunizations are a minimally invasive and cost-effective approach to reducing infections. The objectives…
  • 2019 American Transplant Congress

    Heart En Bloc Thymus Cotransplantation in NHPs

    J. O1, W. Sommer2, K. Pruner3, J. T. Paster4, I. M. Hanekamp1, A. Dehnadi1, I. Rosales1, R. N. Smith1, R. B. Colvin1, G. Benichou1, J. S. Allan1, J. C. Madsen1

    1Center for Transplantation Sciences, MGH, Boston, MA, 2Hannover Medical School, Hannover, Germany, 3University of Washington, Seattle, WA, 4MGH, Boston, MA

    *Purpose: Tolerance of isolated cardiac allografts has never been achieved in NHPs. We investigated whether a cotransplanted, vascularized, donor thymus could induce tolerance of a…
  • 2019 American Transplant Congress

    Deficiency of the Transcription Factor Satb1 in T Cells Promotes Solid Organ Allograft Survival

    P. K. Gupta1, M. L. Miller2, L. Chen1, Y. Wang1, J. Conejo-Garcia3, A. Chong1, M. Alegre1

    1University of Chicago, Chicago, IL, 2University of Pittsburgh, Pittsburgh, PA, 3Moffitt Cancer Center & Research Institute, Tampa, FL

    *Purpose: Conventional CD4+ T cells are key effectors of allograft rejection and novel therapies limiting their response may hold promise in the context of organ…
  • 2019 American Transplant Congress

    Xenorejection of Porcine Islets in Humanized Mice is Dominated by a Human Th17 Cytokine Immune Response

    F. T. Lee1, A. Dangi2, M. Burnette2, B. Hering3, X. Luo2

    1Transplant Surgery, Northwestern University, Chicago, IL, 2Nephrology, Duke University, Durham, NC, 3Diabetes Institute, University of Minnesota, Minneapolis, MN

    *Purpose: We have previously shown that interleukin(IL)-17 producing CD4 T cells (Th17 response) dominate in the early anti-donor immune responses of a pig-to-mouse xenogeneic model…
  • 2019 American Transplant Congress

    Impact of Glomerulitis at 4-Month Biopsy on Long Term Kidney Allograft Outcomes

    M. Whigham, G. Mour, M. Buras, S. Sukumaran Nair, A. Jaramillo, D. Ramon, R. Heilman

    Mayo Clinic, Phoenix, AZ

    *Purpose: Antibody mediated rejection (AMR) is diagnosed based on combination of elevated creatinine, histopathological findings defined as glomerulitis (g), and peritubular capillaritis (ptc), with or…
  • 2019 American Transplant Congress

    Hope Act Donors With Organs Recovered For Transplant: The First Two Years

    W. A. Werbel, O. Kusemiju, B. Barnaba, M. Bowring, B. Doby, C. Kirby, R. Fernandez, Y. Eby, J. Miller, D. Brown, S. Seaman, D. Ostrander, A. Tobian, D. Segev, C. M. Durand

    Johns Hopkins University, Baltimore, MD

    *Purpose: The HOPE Act expands the potential deceased donor pool to include HIV+ donors (HIV D+) and donors with false-positive (FP) HIV screens. The objective…
  • 2019 American Transplant Congress

    Simultaneous Robotic Kidney Transplantation and Bariatric Surgery for Morbidly Obese Patients with End-Stage Renal Failure

    P. West-Thielke, K. A. Tulla, O. T. Okoye, J. A. Almario Alvarez, M. Spaggiari, I. G. Tzvetanov, E. Benedetti

    University of Illinois at Chicago, Chicago, IL

    *Purpose: The purpose of this study is to evaluate the safety and efficacy of simultaneous robotic assisted kidney transplant and robotic assisted sleeve in obese…
  • 2019 American Transplant Congress

    Ex-Vivo Perfusion Mediated Delivery of Rituximab to Clear Latent Epstein-Barr Virus

    T. Ku, M. Cypel, R. V. Ribeiro, V. H. Ferreira, D. Kumar, A. Humar

    UHN, Toronto, ON, Canada

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) can manifest as a B-cell malignancy associated with Epstein-Barr virus (EBV) infection. Risk of PTLD is greatest in EBV D+/R-…
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