ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Effectiveness Of Percutaneous Embolization As Treatment Compared To Nephrectomy For Renal Graft Intolerance Syndrome In Late Graft Failure Patients

    S. Kwon, J. Go, S. Park, S. Yoon, J. Kim, I. Moon

    Department of Vascular and Transplant Surgery, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea, Republic of

    *Purpose: Failed renal allografts left in situ may cause inflammation presenting as graft intolerance syndrome (GIS). But there is no standardization for treatment of a…
  • 2019 American Transplant Congress

    Conversion from Calcineurin Inhibitors to Belatacept in Kidney Recipients with Donor-Specific Anti-HLA Antibodies and Calcineurin Inhibitor Nephrotoxicity Decreases the Pathogenicity of Donor-Specific Anti-HLA Antibodies

    K. Louis1, D. Viglietti1, D. Pievani1, O. Aubert1, D. Glotz1, C. Legendre1, A. Zeevi2, A. Loupy1, C. Lefaucheur1

    1Paris Translational Research Center for Organ Transplantation, Paris, France, 2University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Switching from CNI- to Belatacept-based regimen has been associated with improved graft function in low-immunologic risk kidney recipients. We investigated the efficacy and safety…
  • 2019 American Transplant Congress

    Lower Extremity Impairment and Frailty among Adults with Diabetes Awaiting Kidney Transplantation

    E. Lorenz, A. Kukla, C. Kennedy, R. McCoy, L. Hickson

    Mayo Clinic, Rochester, MN

    *Purpose: Frailty and lower extremity impairment, both indicators of poor physical performance, are predictive of all-cause mortality among patients awaiting kidney transplantation (KT). Diabetes, the…
  • 2019 American Transplant Congress

    Increase in 48 Month Cumulative Acute Rejection Rates in the Most Recent Cohort: The 2018 Transplant Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)

    V. Dharnidharka1, C. Cramer2, A. Chua3, A. Moudgil4, K. Martz5, T. Blydt-Hansen6, J. Smith7, A. Neu, on Behalf of The NAPRTCS Investigators8

    1Washington University in St. Louis, Saint Louis, MO, 2Mayo Clinic, Rochester, MN, 3Duke University, Durham, NC, 4Children's National Medical Center, Washington, DC, 5Emmes Corporation, Rockville, MD, 6BC Children's Hospital, Vancouver, BC, 7Seattle Children's Hospital, Seattle, WA, 8Johns Hopkins University, Baltimore, MD

    *Purpose: The NAPRTCS registry has collected data on children receiving kidney transplants in North America since 1987. The registry has served to document and influence…
  • 2019 American Transplant Congress

    microRNA-375 Provides an Objective Measure of Pancreas Quality in Organ Donors

    I. Shapey1, A. Summers1, J. O'Sullivan1, P. Yiannoullou1, J. Casey2, S. Forbes2, M. Rosenthal3, P. Johnson4, P. Choudhary1, J. Bushnell5, J. Shaw6, N. Hanley1, T. Augustine1, M. Rutter1, D. van Dellen1

    1University of Manchester, Manchester, United Kingdom, 2University of Edinburgh, Edinburgh, United Kingdom, 3Royal Free Hospital, London, United Kingdom, 4University of Oxford, Oxford, United Kingdom, 5Southmead Hospital, Bristol, United Kingdom, 6University of Newcastle, Newcastle, United Kingdom

    *Purpose: Donor pancreatic beta cells are at high risk from apoptosis. Objective methods for assessing the quality of donor pancreases for transplantation are limited. We…
  • 2019 American Transplant Congress

    Tolerance Induction by Myeloid Progenitor Cells Modulates T and B Cell Responses

    J. Domen, Y. Li

    Allergy, Asthma and Immunology, Children's Mercy Hospital, Kansas City, MO

    *Purpose: Modulation of the immune system using cellular therapy is an increasingly attractive option to prevent solid organ graft rejection, while at the same time…
  • 2019 American Transplant Congress

    Association between Respiratory Virus Infections and the Development of De Novo HLA Donor-Specific Antibodies in Lung Transplant Recipients

    M. I. Ali, J. Hata, J. Mallea, M. Elrefaei

    Mayo Clinic, Jacksonville, FL

    *Purpose: The detection of de novo donor-specific anti-HLA antibodies (DSA) post lung transplant have been associated with significantly increased risk for antibody-mediated rejection (AMR) and…
  • 2019 American Transplant Congress

    Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells Regulates Treg Migration and Allograft Protection

    V. Saxena, W. Piao, L. Li, C. M. Paluskievicz, Y. Xiong, T. Simon, J. S. Bromberg

    U Maryland, Baltimore, MD

    *Purpose: Lymphotoxin beta receptor (LTβR) mediated signaling in lymphatic endothelium cells (LEC) is important for migration of regulatory T cells (Treg) to afferent lymphatic vessels…
  • 2019 American Transplant Congress

    The Changing Face of T Cell-Mediated Rejection

    A. Perkowska-Ptasinska and INTERCOMEX investigators1, P. F. Halloran2

    1Medical University of Warsaw, Warsaw, Poland, 2Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada

    *Purpose: We studied how the problem of TCMR in indication biopsies was changing with time by exploring features of 138 biopsies with molecular TCMR in…
  • 2019 American Transplant Congress

    Kidney Transplantation in the Lower-Income Bracket of South Korea; Widening Gap in Accessibility and Inferior Graft Outcome

    G. Park1, S. Park1, J. Kim1, M. Yu1, Y. Kim1, K. Kim1, M. Park2, Y. Kim1, H. Lee1

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Severance Hospital, Seoul, Korea, Republic of

    *Purpose: Kidney transplant (KT) benefits in various aspects of end-stage renal disease (ESRD) patients. However, the financial burden is one of the main obstacles to…
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