Am J Transplant, Volume 19, Suppl 3 Archives - Page 47 of 214 - ATC Abstracts

2019 American Transplant Congress
Need For Protocol Driven Mmr/vzv Serologic Screening
A. Agarwal¹, L. Brumble¹, H. Wadei², C. Libertin¹
¹Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL, ²Department of Transplant, Mayo Clinic, Jacksonville, FL
*Purpose: The current American Society of Transplantation-ID guidelines recommend the MMR and VZV serologic screening pre transplantation for of all persons born after 1956. MMR…
2019 American Transplant Congress
Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant
N. A. Wickramaratne¹, R. Li², R. C. Fyffe-Freil², T. Tian², M. J. Mangino²
¹VCUHealth, Richmond, VA, ²Department of Surgery, VCUHealth, Richmond, VA
*Purpose: Epithelial-to-mesenchymal transition (EMT) is a genetic reprogramming that causes epithelial cells to assume a migratory, mesenchymal phenotype, and it is induced by hypoxia. Ischemic…
2019 American Transplant Congress
CD47 Blockade Promotes Hepatic Macrophage Polarization toward M1 during Normothermic Machine Perfusion of Discarded Human Livers
M. Xu¹, F. Zhou¹, S. Garcia-Aroz¹, B. Banan¹, W. Yang², G. Upadhya¹, K. Byrnes³, B. Wong¹, P. Manning⁴, Y. Lin¹, W. Chapman¹
¹Department of Surgery, Washington University School of Medicine, St. Louis, MO, ²Department of Genetics, Washington University School of Medicine, St. Louis, MO, ³Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, ⁴Arch Oncology, St. Louis, MO, USA, St. Louis, MO
*Purpose: M1 macrophages have been shown to be able to phagocytize dead cells after ischemia-reperfusion injury (IRI). This study investigated the therapeutic effect of CD47…
2019 American Transplant Congress
miRNA Signatures as Prediction Tool for DSA Development and Rejection
M. Hamdorf¹, L. M. Rebellato², K. P. Briley², M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²East Carolina University, Greenville, NC
*Purpose: Early and convenient diagnosis is urgently needed for acute and chronic transplant rejection due to its high risk of the loss of the transplant.…
2019 American Transplant Congress
Functional Dependence, Access to Kidney Transplantation and Waitlist Mortality
A. Muzaale¹, N. Chu¹, H. Ying¹, S. Norman², S. Sison¹, D. Segev¹, M. McAdams-Demarco¹
¹JHU, Baltimore, MD, ²UM, Ann Habor, MI
*Purpose: Among patients with ESRD, functional dependence is common and an important determinant of both HRQOL and adverse outcomes. Kidney transplant (KT) may help patients…
2019 American Transplant Congress
Personality Traits of Liver Transplant Candidates – Unappreciated Challenges
D. Ladner¹, J. Lai², A. N. Hall¹, E. D. Bastarache¹, A. Daud¹, T. Bogg³, A. Lebsack¹, T. Kalume¹, D. Mroczek¹
¹Northwestern University, Chicago, IL, ²UCSF, San Francisco, CA, ³Wayne State University, Chicago, IL
*Purpose: Liver transplant candidates are chronically ill, requiring complex medical care prior to and after transplant to optimize outcomes. Conscientiousness is one of the Big…
2019 American Transplant Congress
First UK Experience of the Molecular Microscope (MMDX™) in the Kidney Transplant Clinic
C. Lawrence¹, S. Thiru², A. Manoj¹, S. Fluck¹
¹Renal Medicine, The Lister Hospital, Stevenage, United Kingdom, ²Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom
*Purpose: Molecular diagnostic methods are now included in the Banff classification of kidney transplant pathology. Traditional histopathology may be limited by intra/inter pathologist variation. The…
2019 American Transplant Congress
Donor, Recipient Indices and Frailty Predict Outcomes after Heart-Kidney Transplantation
C. Beifeld¹, V. Dio Guardi¹, K. Lau¹, A. Di Carlo¹, S. Karhadkar²
¹Surgery, Temple University Hospital, Philadelphia, PA, ²Temple University Hospital, Philadelphia, PA
*Purpose: Simultaneous heart kidney transplantation (SHKT) is increasing in frequency; however there is a lack of consensus regarding patient selection criteria for this life saving…
2019 American Transplant Congress
Alteration of Myocardial Velocities and T1 Times in Patients with Acute Cellular Rejection during First Year Post Heart Transplant
R. Sarnari, A. Ruh, M. Abbasi, J. Blaisdell, R. Dolan, J. Wilcox, S. Khan, E. Vorovich, J. Rich, A. Anderson, C. Yancy, J. Carr, M. Markl, K. Ghafourian
Northwestern University, Chicago, IL
*Purpose: We hypothesize that acute cellular rejection (ACR) episodes during the first year post heart transplant (HTx) may lead to structural and functional alterations of…
2019 American Transplant Congress
One Organ Procurement Organization’s Uncontrolled Donation After Cardiocirculatory Death Program Increases The Donor Pool And Results In The Transplantation Of 254 Organs
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: To demonstrate that an effective DCD program can lead to an increase in the procurement of transplantable organs with satisfactory transplant outcomes from uncontrolled…