Am J Transplant, Volume 19, Suppl 3 Archives - Page 47 of 214 - ATC Abstracts

2019 American Transplant Congress
Outcomes of Liver Transplantation for Hepatocellular Carcinoma in Septuagenarians
M. Najjar¹, K. Bruestle¹, P. Jiang¹, E. Lieberman¹, R. Hwang¹, A. Mathur¹, E. C. Verna¹, A. Griesemer¹, B. Samstein², T. Kato¹, Y. M. Saenger¹, K. J. Halazun², J. C. Emond¹
¹Columbia University Medical Center, New York, NY, ²Weill Cornell Medicine, New York, NY
*Purpose: The impact of advanced age on liver transplantation (LT) for hepatocellular carcinoma (HCC) has not been well studied. We sought to compare post-OLT survival…
2019 American Transplant Congress
Natural Course Of Tacrolimus Intra-patient Variability In Liver Transplant Recipients
N. Wilson, S. Tremblay, N. S. Ejaz, K. Zheng, J. Garrett, S. A. Shah, R. R. Alloway, T. E. Kaiser
University of Cincinnati, Cincinnati, OH
*Purpose: The evolution of tacrolimus (TAC) intra-patient variability (IPV) post liver transplant (LT) remains to be characterized. Identification of factors associated with high TAC-IPV may…
2019 American Transplant Congress
Phenotypic and Functional Analysis of Non-Activated and Allo-Activated Eomesodermin+ CD8+ T Cells in Humans and Nonhuman Primates
A. Perez Gutierrez¹, A. W. Thomson², D. M. Metes², M. B. Ezzelarab²
¹Transplantation Institute, University of Chicago Medicine, Chicago, IL, ²Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
*Purpose: The T-box transcription factors Eomesodermin (Eomes) and T-bet play a critical role in differentiation and function of CD8+ memory T cells (Tmem). We have…
2019 American Transplant Congress
The Immunomodulatory Role of Type I Interferons in Alloimmunity
I. Sulkaj, H. Allos, S. K. Eskandari, J. M. Safadi, J. Y. Choi, B. S. Al Dulaijan, E. Al-Hussain, S. Cai, J. R. Azzi
Medicine, Brigham and Women's Hospital, Boston, MA
*Purpose: Despite a growing body of work on type 1 interferon (IFNAR1) signaling, there is a lack of consensus on the immunological properties of type…
2019 American Transplant Congress
Developing a Patient Specific Search: Feedback from Kidney Transplant Candidates and Recipients
W. T. McKinney¹, M. J. Bruin², C. R. Schaffhausen¹, S. Chu², J. Snyder³, A. Matas⁴, B. Kasiske⁵, A. K. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, St. Paul, MN, ³Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: Patients in need of kidney transplantation face numerous obstacles when identifying a transplant center for treatment. Acceptance criteria, waiting time, and post-transplant allograft survival…
2019 American Transplant Congress
Costs In Contemporary Transplant Practice
M. Wyld, T. Ying, K. Wyburn, S. Chadban
Renal Department, Royal Prince Alfred Hospital, Camperdown, Australia
*Purpose: The cost of kidney transplantation, in the context of increasing immunological and medical complexity and higher donor and recipient age, remains uncertain. In 2009,…
2019 American Transplant Congress
The lncRNA-mRNA Co-Expression Analysis in Acetaminophen-Induced Liver Injury
J. Zheng, F. Xue
Liver Surgery and Liver Transplantation Center, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
*Purpose: Acetaminophen (APAP) could cause liver injury, or even acute liver failure, accounting for approximately one-half of all cases in developed countries. Once acute liver…
2019 American Transplant Congress
Identifying Barriers to Organ Donation among Asians Americans
M. T. Li, G. C. HIllyer, S. Mohan
Columbia University Medical Center, New York, NY
*Purpose: Queens County, NY, one of the most densely populated and most diverse areas in the country with >27% Asian but has one of the…
2019 American Transplant Congress
Long-Term Efficacy of Direct-Acting Antiviral Agents
J. Zhang, W. Sun, J. Lin, Y. Tian, L. Ma, L. Zhang, Y. Zhu
Beijing Friendship Hospital, Capital Medical University, Beijing, China
*Purpose: Long-term efficacy of direct-acting antiviral agents (DAAs) therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort…
2019 American Transplant Congress
Innate Immunity in Brain Dead Donors: Implications of Necroptosis in Kidney Allograft Outcomes
A. Ang¹, A. Zmijewska², T. M. Stevens³, J. Murphy¹, R. B. Mannon²
¹School of Medicine, UAB, Birmingham, AL, ²Medicine/Nephrology, UAB, Birmingham, AL, ³Pathology, UAB, Birmingham, AL
*Purpose: Regulated necrosis (necroptosis) has been implicated in renal injury from nephrotoxic agents and ischemia. With the use of suboptimal brain dead donors (BDDs) to…