Am J Transplant, Volume 19, Suppl 3 Archives - Page 4 of 214 - ATC Abstracts

2019 American Transplant Congress
Regulating T Cell Responses by Forced Transgenic Expression of Decay-Accelerating Factor
D. Heja¹, Z. He¹, S. A. Lira¹, F. Lin², D. Homann¹, P. S. Heeger¹
¹Icahn School of Medicine at Mount Sinai, New York, NY, ²Cleveland Clinic, Cleveland, OH
*Purpose: Decay-accelerating factor (DAF, CD55) is a cell surface expressed, glycophosphatidylinositol-(GPI)-anchored, complement regulator. Previous studies showed that during cognate T cell/antigen presenting cell (APC) interactions…
2019 American Transplant Congress
Factors Associated with Subclinical Cardiovascular Damage after Pediatric Liver Transplantation: A Longitudinal Observational Study
N. Memaran¹, I. Goldschmidt¹, B. Borchert¹, R. I. Sugianto¹, H. Wilke¹, R. Blöte¹, U. Baumann¹, E. Bauer¹, A. von Wick¹, N. Junge¹, C. Leiskau¹, E. D. Pfister¹, N. Richter², B. M. Schmidt³, A. Melk¹
¹Department of Pediatric Kidney, Liver, and Metabolic Diseases, Hannover Medical School, Hannover, Germany, ²Department of General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany, ³Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany
*Purpose: Cardiovascular (CV) events account for 8-13% of deaths after liver transplantation (LT) in adulthood. While CV risk factors are present in children after LT…
2019 American Transplant Congress
Kidney Paired Donation Transplant Outcomes: Experiences from the First Ten Years of the National Kidney Registry
D. B. Leeser¹, A. G. Thomas², A. A. Shaffer², J. Veale³, A. B. Massie², M. Cooper⁴, S. Kapur⁵, S. Kapur⁵, S. Kapur⁵, N. Turgeon⁶, D. Segev², A. Waterman³, S. Flechner⁷
¹East Carolina Univ Sch of Med, Greenville, NC, ²Johns Hopkins, Baltimore, MD, ³UCLA, Los Angeles, CA, ⁴Georgetown, Washington, DC, ⁵Weill Cornell Medical School, New York, NY, ⁶Emory, Atlanta, GA, ⁷Cleveland Clinic, Cleveland, OH
*Purpose: In the United States (US), kidney paired donation (KPD) networks have facilitated an increasing proportion of KTs annually, but longer-term transplant outcomes and differences…
2019 American Transplant Congress
Epidemiology and Outcomes of BKV Nephropathy Management by Screening Policy in a Real-Life Setting
V. D. GARCIA¹, F. V. Raupp¹, G. MEINERZ¹, K. Piegas², E. KEITEL¹
¹Nephrology and Kidney and Pancreas Transplant Department, ISCMPA, Porto Alegre, Brazil, ²Pathology Department, ISCMPA, Porto Alegre, Brazil
*Purpose: To verify the frequency of BKVAN in a single center's clinical setting and evaluate the response to immunosuppressive adjustments through graft survival analysis.*Methods: Retrospective…
2019 American Transplant Congress
Assessing Pressure to Donate among Potential Living Kidney Donors
D. R. Helfer¹, J. Stanton², E. A. King¹, A. K. Eno¹, J. M. Ruck¹, A. A. Shaffer¹, A. G. Thomas¹, M. M. Waldram¹, A. M. Cameron¹, J. Kahn¹, L. Erby¹, M. L. Henderson¹, D. L. Segev¹, J. M. Garonzik Wang¹
¹Johns Hopkins University, Baltimore, MD, ²East Carolina University, Greenville, NC
*Purpose: In the setting of ongoing methods to increase living donation, including novel methods that harness the power of social media, it is imperative that…
2019 American Transplant Congress
Basiliximab versus T-cell Depleting Induction Therapy in Elderly Kidney Transplant Recipients
G. Vranic, H. Shah, B. Thomas, B. Javaid, J. Moore, M. Cooper, A. Gilbert
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: The ideal induction therapy for elderly kidney transplant recipients is not known. Given concerns about increased risk of infection and malignancy and perceived decreased…
2019 American Transplant Congress
Circulating Donor T and NK Cells in Lung Transplantation Recipients Are Derived from the Donor Lung Parenchyma and Represent Tissue-Resident Memory Cells
J. F. Kuehne¹, R. Ballmàs Sanz¹, A. Hitz¹, B. Wiegmann², K. A. Bläsing¹, F. Ius², A. Knoefel², I. Tudorache², M. Avsar², D. Jonigk³, A. Haverich², G. Warnecke², C. Falk¹
¹Institute of Transplant Immunology, Hannover Medical School (MHH), Hannover, Germany, ²Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School (MHH), Hannover, Germany, ³Institute of Pathology, Hannover Medical School (MHH), Hannover, Germany
*Purpose: We previously identified donor lymphocytes in peripheral blood of recipients directly after transplantation and persisting at least three weeks that were characterized by the…
2019 American Transplant Congress
Lineage Tracing Identifies C-Kit Cells as a Population of Kidney-Specific Stem Cells during Development and in Acute and Chronic Kidney Diseases
E. B. Rangel¹, E. Higuti-Sousa¹, G. Goss², B. Goldstein², B. Seidler³, D. Saur³, S. A Gomes⁴, J. M. Hare²
¹Albert Einstein Hospital, São Paulo, Brazil, ²University of Miami, Miami, FL, ³Medizinische Klinik, Technische Universität München, Munich, Germany, ⁴University of São Paulo, São Paulo, Brazil
*Purpose: We recently reported that c-Kit cells isolated from developing kidneys exhibit regenerative potential in mouse models of acute nephrotic syndrome and ischemia-reperfusion injury. These…
2019 American Transplant Congress
Using Liver Transplant (LT) Data And Analytics to Improve Program Clinical and Financial Performance
A. Bonham¹, Z. Tulu², W. Concepcion¹, A. Gallo¹, M. Melcher¹, P. Kwo¹, A. Ahmed¹, C. Esquivel¹
¹Stanford University Medical School, Palo Alto, CA, ²Stanford Health Care, Palo Alto, CA
*Purpose: In 2017, we developed a simple algorithm for use prior to transplantation to determine risk of fatal outcome. Pre-transplant organ system failure risk factors…
2019 American Transplant Congress
Donate HCV Trial: Transplanting Thoracic Organs from Hepatitis C Donors to Uninfected Patients
A. E. Woolley¹, S. K. Singh², H. J. Goldberg³, M. M. Givertz⁴, M. R. Mehra⁴, A. Coppolino, III⁵, V. Cheng¹, J. Fanikos⁶, D. P. Harrington⁷, H. R. Mallidi², L. R. Baden¹
¹Infectious Diseases, Brigham and Womens Hospital, Boston, MA, ²Cardiac and Thoracic Surgery, Brigham and Womens Hospital, Boston, MA, ³Pulmonary, Brigham and Womens Hospital, Boston, MA, ⁴Cardiology, Brigham and Womens Hospital, Boston, MA, ⁵Thoracic Surgery, Brigham and Womens Hospital, Boston, MA, ⁶Pharmacy, Brigham and Womens Hospital, Boston, MA, ⁷Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
*Purpose: Given the need for thoracic organs and the high mortality of patients awaiting heart or lung transplantation, it is imperative to find ways to…