ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    CURATE.AI: Personalized Liver Transplant Tacrolimus Dosing

    A. Zarrinpar1, T. Kee2, P. Wang3, J. Khong3, U. Kim1, J. Chong2, J. B. Jeong3, A. T. Truong2, S. Tan2, B. K. Betzler2, W. Ng2, C. Ho3, D. Ho2

    1Surgery, University of Florida, Gainesville, FL, 2National University of Singapore, Singapore, Singapore, 3UCLA, Los Angeles, CA

    *Purpose: Transplant immunosuppressive regimens include multiple drugs with varying pharmacokinetics, metabolic pathways, and drug-drug interactions. This study aimed to use CURATE.AI, an artificial intelligence platform,…
  • 2019 American Transplant Congress

    Lower Alcohol Taxes Are Associated with Increased Liver Transplant Listing

    N. T. Shen1, M. Raver1, N. Hutchison1, A. Jesudian1, J. Bray2, B. Schackman3, R. S. Brown1

    1Medicine; Division of Gastroenterology and Hepatology, New York Presbyterian Hospital - Weill Cornell, New York, NY, 2Economics, University of North Carolina at Greensboro, Greensboro, NC, Greensboro, NC, 3Healthcare Policy and Research, Weill Cornell Medicine, New York, NY

    *Purpose: Alcoholic liver disease (ALD) is a leading indication for liver transplantation worldwide with rising prevalence. Whether relationships exist between transplant listing for ALD and…
  • 2019 American Transplant Congress

    Redox State of HMGB1 Drives Ischemia-Reperfusion Injury in Human Liver Transplantation

    R. A. Sosa1, A. Q. Terry1, J. Nevarez-Mejia1, M. Rossetti1, B. V. Naini1, V. M. Groysberg1, F. M. Kaldas2, R. W. Busuttil2, D. W. Gjertson1, J. W. Kupiec-Weglinski2, E. F. Reed1

    1Pathology & Laboratory Medicine, UCLA, Los Angeles, CA, 2Surgery, UCLA, Los Angeles, CA

    *Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor of acute and chronic graft rejection in orthotopic liver transplantation (OLT) involving a complex interplay between…
  • 2019 American Transplant Congress

    Obese Simultaneous Pancreas And Kidney Transplant Recipients In Type 2 Diabetes Have Similar Risks Of Pancreas Failure As Non-obese

    T. Alhamad1, K. Espinoza1, J. R. Wellen1, S. Chang1, D. C. Brennan2, K. L. Lentine3

    1Washinton University in St. Louis, St. Louis, MO, 2Johns Hopkins University, Baltimore, MD, 3Saint Louis University, St. Louis, MO

    *Purpose: In October 2014, United Network for Organ Sharing (UNOS) implemented criteria for simultaneous pancreas and kidney transplant (SPKT) in patients with c-peptide 2 >…
  • 2019 American Transplant Congress

    Pancreas Allograft Importation Should Be Fostered by Any Transplant Center Challenged by Excessively Long Waitlist Times

    J. Torabi, J. P. Rocca, L. Lirano, Y. Azzizi, M. Ajaimy, C. Pynadath, E. Akalin, M. Kinkhabwala, J. A. Graham

    Montefiore Medical Center, Bronx, NY

    *Purpose: Pancreas transplantation is a durable option for patients with insulin dependent diabetes. However, geographic inequity has created a supply side problem for our region.…
  • 2019 American Transplant Congress

    Pre-Operative C-Peptide Predicts Weight Gain after Pancreas Transplantation

    J. Torabi, J. P. Rocca, E. Kestenbaum, M. Ajaimy, M. Kinkhabwala, J. A. Graham

    Montefiore Medical Center, Bronx, NY

    *Purpose: Transplant recipients are susceptible to metabolic syndrome as typified by hyperglycemia, central obesity and increased insulin resistance after transplant, which may precede the onset…
  • 2019 American Transplant Congress

    Prevalence of Non-Adherence to Immunosuppressive Medications in Kidney Transplant Recipients, Barriers and Predictors

    S. Taj1, H. Baghaffar2, D. Alnajjar2, N. Almashabi3, S. Ismail4

    1King Saud Bin Abdulaziz University For Health Sciences, Jeddah, Saudi Arabia, 2Ibn Sina College, Jeddah, Saudi Arabia, 3Umm Al-Qura University, Makkah, Saudi Arabia, 4Pharmaceutical Care Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia

    *Purpose: Non-adherence to immunosuppressant therapy (IST) is one of the major factors leading to graft rejection. To our knowledge, limited data exist on the prevalence…
  • 2019 American Transplant Congress

    Racial Differences in Cancer Mortality for Kidney Transplant Recipients

    K. Cordrey, J. Motter, A. Kernodle, K. Jackson, M. Camp, T. Purnell, D. Segev, J. Garonzik Wang

    Johns Hopkins University, Baltimore, MD

    *Purpose: Cancer is the second leading cause of post-transplant mortality. Since racial disparities have been reported in many aspects of transplant care, we sought to…
  • 2019 American Transplant Congress

    Long Term Follow-Up of the Use of Checkpoint Inhibitors in Kidney Transplant Recipients

    K. Venkatachalam, R. Delos Santos, T. Alhamad

    Transplant nephrology, Washington University, St. Louis, MO

    *Purpose: To report the long term impact of check point inhibitors in patient and allograft survival among kidney transplant recipients.*Methods: We report follow up of…
  • 2019 American Transplant Congress

    EBV+ PTLD in the Modern Immunosuppression Era: Role of EBV Serology and DNAemia-Preliminary Data from CTOT-C06

    O. M. Martinez1, S. M. Krams1, M. A. Robien2, M. Lapasaran1, S. D. Boyd1, B. Armstrong3, C. Twist4, K. Weinberg1, D. Gratzinger1, B. Tan1, M. Sever3, D. Ikle3, M. Brown2, D. Bernstein1, C. O. Esquivel1

    1Stanford University Sch of Med, Stanford, CA, 2NIAID/NIH, Rockville, MD, 3Rho, Chapel Hill, NC, 4Roswell Park, Buffalo, NY

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOT-C)-06 is an…
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