Am J Transplant, Volume 19, Suppl 3 Archives - Page 26 of 214 - ATC Abstracts

2019 American Transplant Congress
A Prognostic Biomarker to Estimate the Likelihood of Developing De Novo Donor Specific Antibody in Kidney Transplant Recipients
S. Kawakita¹, L. M. Rebellato², K. P. Briley², A. Q. Maldonado³, C. E. Haisch², P. Bolin², S. A. Kendrick⁴, H. Jones⁴, K. McLawhorn⁴, D. Leeser², V. Jucaud¹, V. Burnett¹, M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²East Carolina University, Greenville, NC, ³Vidant Medical Center, Greenville, NC, ⁴Eastern Nephrology Associates, Greenville, NC
*Purpose: Evaluation of human leukocyte antigen (HLA) mismatch at antibody epitope level rather than antigen level may explain better the impact of HLA mismatch on…
2019 American Transplant Congress
High Urinary Neutrophil Gelatinase Lipocalins (NGAL) Levels in Kidney Perfusates as Predictor of a Better Renal Function
A. Angeletti, C. Donadei, V. De Pace, I. Capelli, V. Corradetti, C. Zannini, F. Alviano, L. Bonsi, G. Comai, M. Ravaioli, G. La Manna
DIMES, S.Orsola-Malpighi Hospital, Bologna University, Bologna, Italy
*Purpose: Neutrophil gelatinase-associated lipocalin (NGAL) has recently emerged as a biomarker of different conditions, but the biological role remains unclear. We hypnotized that NGAL has…
2019 American Transplant Congress
Cell Coding Transcriptomic Analysis Of Serial Blood And Biopsy Samples In A Large Cohort Of Kidney Transplant Recipients
W. Zhang¹, Z. Yi¹, Z. Sun¹, K. Keung², C. Wei¹, C. Xi¹, S. Farouk¹, M. Menon¹, P. Cravedi¹, P. O'Connell², B. Murphy¹
¹Icahn School of Medicine at Mount Sinai, New York, NY, ²The University of Sydney, Sydney, Australia
*Purpose: Whole blood and graft biopsy RNA expression analyses are limited by the heterogeneous cell composition of the samples. Cell coding is an analytical tool…
2019 American Transplant Congress
Utilizing Imagestream Technology to Determine Hepatocellular CD38 Localization
Y. Lee, J. Kim, B. F. Reader, C. Akateh, K. R. Maynard, K. W. Washburn, J. L. Zweier, B. A. Whitson, S. M. Black
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: CD38 is an ecto-enzyme that modulates intracellular calcium levels by producing potent secondary messengers, which utilize the cellular NAD pool and lead to increased…
2019 American Transplant Congress
CD56+CD57+ Infiltrate is a Predominant Subset of Infiltrating Natural Killer Cell in Renal Transplant Biopsies with Antibody-Mediated Rejection
H. Jung¹, Y. Wee², J. Kim², M. Choi², J. Choi², H. Kwon², J. Jung², S. Kim³, Y. Cho⁴, Y. Park⁴, H. Go⁴, M. Han⁵, Y. Kim², D. Han², S. Shin²
¹Department of Biomedical Science, Asan Medical Institute of Convergence Science and Technology (AMIST), Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ²Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ³Department of Convergence Medicine, Asan Institute for life sciences, Asan Medical Center, Seoul, Korea, Republic of, ⁴Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ⁵Department of Clinical Epidemiology, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: To verify a subset of intragraft and circulating natural killer cells associated with kidney allograft rejection and fibrosis.*Methods: Thirty-nine clinically indicated transplant biopsies performed…
2019 American Transplant Congress
Graft Survival of Fourth Time Renal Transplant Recipients Are Similar to Third Time Transplants: A SRTR Database Analysis
B. Petrun, R. Nygaard, M. Hill, C. Richardson, A. Israni, P. Stahler
Hennepin County Medical Center, Minneapolis, MN
*Purpose: The number of candidates for repeat kidney transplant in the United States has steadily increased over the last 30 years. Second and third kidney…
2019 American Transplant Congress
Transplantation of the Highly Sensitized Renal Transplant Candidate in the Post-KAS Era: Who is Left Out?
C. Schinstock, B. Smith, A. Bentall, M. Stegall
Mayo Clinic, Rochester, MN
*Purpose: Highly sensitized kidney transplant candidates are given high priority under the new kidney allocation system (KAS), but it is unclear if all sensitized candidates…
2019 American Transplant Congress
Conversion from Tacrolimus Immediate Release to Tacrolimus Extended Release (Envarsus XR®): A Real World Cohort Highlighting Dosing Variability among Patients
K. D. Belfield¹, D. Malhotra², M. Waleed³, E. A. Cohen¹
¹Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, ²Yale University School of Medicine, New Haven, CT, ³University of Connecticut School of Pharmacy, Storrs, CT
*Purpose: Tacrolimus extended release (TacER) (Envarsus XR®) has become an attractive alternative to tacrolimus immediate release (TacIR) due to its once daily dosing scheme, favorable…
2019 American Transplant Congress
Delayed Achievement of Therapeutic Tacrolimus Levels with De Novo Extended-Release Tacrolimus Tablets and the Incidence of Rejection in Kidney Transplant Patients
C. E. Carthon¹, J. C. Hagopian¹, S. E. January¹, A. Gharabagi¹, R. Delos Santos², T. A. Horwedel³
¹Pharmacy, Barnes-Jewish Hospital, Saint Louis, MO, ²Nephrology, Washington University School of Medicine, Saint Louis, MO, ³Veloxis Pharmaceuticals, Inc., Cary, NC
*Purpose: Early therapeutic tacrolimus levels have been associated with improved outcomes in renal transplant recipients while lower exposure to tacrolimus during the first week of…
2019 American Transplant Congress
Early Rejection Outcomes with IL-2 vs. ATG Induction among Kidney Transplant Recipients Induction Differences with Early Steroid Withdrawal
C. Burelli, A. Szczepanik, K. Yadav, E. Sanchez, M. Debroy, V. Humphreville, J. Rabets, A. Padiyar, N. Sarabu, A. Jittirat, A. Palanisamy, K. Chavin
University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Early steroid withdrawal in kidney transplant (Ktx) patients is controversial and has demonstrated an increased risk of acute rejection with similar long-term outcomes. Data…