Am J Transplant, Volume 19, Suppl 3 Archives - Page 23 of 214 - ATC Abstracts

2019 American Transplant Congress
Targeting Pyroptosis in Brain-Dead Donors Improves Renal Function after Transplantation in Rat
H. Yang¹, Y. Shi², X. Li¹, L. Luo¹, C. Long¹, Y. Xiong³, M. Chen⁴, J. Gao⁴, H. Li⁵, Z. Wang⁵
¹Department of Organ Transplantation, People's Hospital of Jiangxi Province, Nanchang, China, ²Department of Pathology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ³Department of Neurology, People's Hospital of Jiangxi Province, Nanchang, China, ⁴Department of Vascular Surgery, People's Hospital of Jiangxi Province, Nanchang, China, ⁵Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
*Purpose: Pyroptosis is a form of programmed cell death include necrosis, nuclear condensation, and release of proinflammatory after caspase-1 activation. It is unknown whether pyroptosis…
2019 American Transplant Congress
Peripheral Blood Chemokine Levels in Kidney Allograft Rejection
E. Van Loon, D. Schols, S. Claes, M. Naesens
University Hospitals Leuven, Leuven, Belgium
*Purpose: Cytokines and chemokines play a critical role in acute rejection after kidney transplantation and may be of importance in the quest for better diagnostic…
2019 American Transplant Congress
Association of Histological Findings in Renal Graft Biopsy with Non-Adherence to Immunosuppressive Treatment
B. D. Cardoso¹, J. Montagner², K. Pegas³, R. Kist⁴, J. Neumann⁵, H. S. Pinheiro⁶, V. D. Garcia⁴, E. Keitel¹
¹Department of Nephrology and Kidney Transplantation/ Post Graduation Program in Pathology, Irmandade Santa Casa de Misericórdia/ Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil, ²Transplant Immunology Laboratory,, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, ³Department of Pathology, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, ⁴Department of Nephrology and Kidney Transplantation, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, ⁵Transplant Immunology Laboratory, Irmandade Santa Casa de Misericórdia, Porto Alegre, Brazil, ⁶Renal Transplant Unit, NIEPEN/NIDEAL (UFJF), Porto Alegre, Brazil
*Purpose: Non-adherence to immunosuppressive treatment after renal transplantation is a frequent issue, but the magnitude of its impact has been debated. It is unknown whether…
2019 American Transplant Congress
Calcineurin Inhibitors and Long-Term Outcomes of Kidney Transplantation from Thai Transplant Registry
S. Udomkarnjananun, N. Townamchai, Y. Avihingsanon, K. Praditpornsilpa
Chulalongkorn University, Bangkok, Thailand
*Purpose: Calcineurin inhibitors (CNIs) have became the primary immunosuppressive medications (IS) for kidney transplantation (KT) in the current era. However, the long-term outcomes of KT…
2019 American Transplant Congress
Impact of Delayed Graft Function on Allograft Survival in DCD versus DBD Kidneys
T. Ishaque, A. B. Massie, J. Ruck, C. Holscher, J. G. Wang, D. L. Segev
Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Several single-center studies have suggested no link between delayed graft function (DGF) and graft survival in recipients of donation after cardiac death (DCD) kidneys,…
2019 American Transplant Congress
Assessment of Health-Related Quality of Life and Graft Failure among Kidney Transplant Patients in the Benefit and Benefit-EXT Trials
I. Purnajo¹, J. L. Beaumont¹, M. Polinsky², E. Alemao², M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Bristol Myers Squibb, Princeton, NJ
*Purpose: To achieve patient focused drug development in renal transplant, we need to better understand how the patient’s perspective of health-related quality of life (HRQoL)…
2019 American Transplant Congress
Self-reported Marijuana Use In Kidney Transplant Candidates And Its Association With Access To Transplantation
S. Rodriguez Ramirez, E. Tang, O. Famure, A. Bansal, J. Kim, I. Mucsi
Kidney Transplant, Toronto General Hospital, Toronto, ON, Canada
*Purpose: In light of the current legislative changes in Canada, and the variable approach to marijuana use in the United States, it is important to…
2019 American Transplant Congress
Diagnostic Efficacy of Color Doppler Ultrasound on Recipients with Transplanted Renal Artery Stenosis: A Single Center Experience
Y. Yang, Z. Wang, S. Fei, H. Chen, L. Sun, Z. Han, J. Tao, X. Ju, R. Tao, M. Gu
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: Our study was to explore the diagnostic efficacy of Color Doppler ultrasound (CDUS) on the diagnosis of allogeneic transplanted renal artery stenosis (TRAS) during…
2019 American Transplant Congress
The Molecular Pathology of Immune Checkpoint Inhibitor-Associated Renal Allograft Rejection: Overlap with Acute Interstitial Nephritis
B. Adam¹, C. Boils², L. Bu³, K. Renaudin⁴, K. Wen¹, M. Mengel¹
¹University of Alberta, Edmonton, AB, Canada, ²Arkana Labs, Little Rock, AR, ³University of Minnesota, Minneapolis, MN, ⁴CHU Nantes, Nantes, France
*Purpose: The use of immune checkpoint inhibitors (ICIs) for various malignancies has been associated with numerous immunological adverse events, including acute interstitial nephritis (AIN) in…
2019 American Transplant Congress
Comparison of Long-Term Outcomes between Alemtuzumab and Rabbit Anti-Thymocyte Globulin for Acute Kidney Allograft Rejection
M. van der Zwan, M. C. Clahsen-van Groningen, D. L. Roelen, M. W. van den Hoogen, M. Van Agteren, J. I. Roodnat, C. C. Baan, D. A. Hesselink
Erasmus MC, Rotterdam, Netherlands
*Purpose: T cell-depleting antibody therapy with rabbit anti-thymocyte globulin (rATG) is the treatment of choice for glucocorticoid-resistant, recurrent and/or severe acute kidney allograft rejection (AR).…