2019 American Transplant Congress
Halt-hcc At The Time Of Listing Is Superior To Other Allocation Metrics At Predicting Waitlist Dropout; An Srtr Analysis
*Purpose: A recently developed liver allocation metric, Hazard Associated with Liver Transplant for Hepatocellular Carcinoma (HALT-HCC), has been shown to predict post-transplantation survival and recurrence.…2019 American Transplant Congress
Outcomes and Clinical Utility of the kSORT Assay in the Prism Prospective Clinical Trial of Highly Sensitized Kidney Transplant Recipients
Department of Surgery, UCSF, San Francisco, CA
*Purpose: kSORT, a 17 gene blood biomarker, has been retrospectively validated for detection of biopsy proven acute rejection (AR) and immune quiescence in kidney transplantation…2019 American Transplant Congress
Normothermic Ex-Vivo Kidney Perfusion Preservation Consistently Improves Extreme Marginal Graft Function Compared to Hypothermic Machine Perfusion
*Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) is an emerging technique for renal graft preservation. We investigated whether NEVKP promoted improved marginal graft function compared to…2019 American Transplant Congress
Women Who Undergo Liver Transplant Have Increased Health Care Utilization in the Peri-Transplant Period Compared with Men
*Purpose: We have previously shown that women on the liver transplant (LT) waitlist are at greater risk of hospitalization compared with men, but whether this…2019 American Transplant Congress
Intact Lymphatics Are Essential for Costimulation Blockade-Induced Lung Allograft Survival
*Purpose: Blocking lymphangiogenesis is thought to diminish immune responses to donor tissues. However, lung transplantation (Tx), which involves airway and vascular but not lymphatic anastomoses,…2019 American Transplant Congress
Depletional Induction Therapy in Non-Human Primates – Preclinical Modeling of Polyclonal Depletion with Rhesus-Specific ATG
*Purpose: Antithymocyte globulins (ATG) have been used in transplantation since the late 1960s to prevent and treat acute allograft rejection. Over the past decade, induction…2019 American Transplant Congress
Effects of Standard Drug Immunosuppression on Peripheral Transitional B Cells and Gene Expression in Non-Human Primates
*Purpose: Operationally tolerant renal transplant recipients exhibit an increased number of transitional B cells and an upregulation of selected B-cell associated genes in the periphery…2019 American Transplant Congress
Increasing Expression of B-cell Maturation Antigen during the Development of Recall Antibody Responses: A Prospective Pharmaceutical Target for B-cell Suppression?
Cedars-Sinai Med Ctr, Los Angeles, CA
*Purpose: Our previous study found that B cell maturation antigen (BCMA) is increasingly expressed by B/plasma cells during the development of de novo alloantibody responses.…2019 American Transplant Congress
Deceased Donor Vascularized Abdominal Wall Allograft Procurement – Lessons Learned from Early Experiences
Abdominal Transplant Surgery, Duke University Medical Center, Durham, NC
*Purpose: Vascularized abdominal wall allografts (AWA), which protect solid organs in patients with loss of abdominal domain or extensive abdominal wall damage, remain an essential…2019 American Transplant Congress
Differential Regulation of Phosphokinases by Anti-HLA Class I and 11 Antibodies
*Purpose: Anti-HLA antibodies, both pre-formed and de novo are associated with worse graft survival. Glomerular endothelial cells are the targets for antibody mediated rejection. We…
American Transplant Congress abstracts