Am J Transplant, Volume 19, Suppl 3 Archives - Page 21 of 214 - ATC Abstracts

2019 American Transplant Congress
Nephrotoxicity Caused by Calcineurin Inhibitors is Meditated by BAX, NOL3 and XIAP Apoptotic Genes Dysregulation
G. Queipo¹, M. Fonsecha-Sanchez¹, J. Sanchez¹, L. Garcia¹, M. Carmona², E. Villanueva¹, G. Melendez¹, L. Morales-Buenrostro³, M. Alamilla¹
¹Hospital General de Mexico-Eduardo Liceaga Facultad de Medicina UNAM, Mexico City, Mexico, ²Facultad de Medicina UNAM, Mexico City, Mexico, ³Instituto Nacional de Ciencias Médicas Salvador Zubirán, Mexico City, Mexico
*Purpose: Calcineurin inhibitors (CNI) remain the most effective and widely used immunosuppressive agents in kidney transplantation. Nephrotoxicity is a major secondary effect, and renal biopsy…
2019 American Transplant Congress
Reference Ranges Donor-Derived Cell-Free DNA in a Heart Transplant Population
A. Kao¹, S. Dholakia², M. Deng³
¹Saint Luke's, Kansas City, MO, ²CareDx, Brisbane, CA, ³University of Los Angeles, Los Angeles, CA
*Purpose: Elevations in donor-derived cell-free DNA (dd-cfDNA) ≥0.20 % in heart transplant recipients (HTR) has been shown to be associated with a probability of acute…
2019 American Transplant Congress
Liver Allograft Provides Protection Against Cardiac Allograft Rejection In Combined Heart And Liver Transplantation
K. Zhao¹, R. Wang², M. Kamoun³, K. Olthoff¹, M. Hoteit⁴, E. Rame⁵, M. Levine¹, R. Mclean⁵, P. Abt¹
¹Surgery, University of Pennsylvania, Philadelphia, PA, ²Jefferson University, Philadelphia, PA, ³Pathology, University of Pennsylvania, Philadelphia, PA, ⁴Gastroenterology, University of Pennsylvania, Philadelphia, PA, ⁵Cardiology, University of Pennsylvania, Philadelphia, PA
*Purpose: Combined heart-liver transplant (CHLT) is indicated for patients with combination of heart and liver disease or amyloid heart disease for whom liver transplant can…
2019 American Transplant Congress
Trends in Utilization of Deceased Donor Kidneys Based on Donor Hep C Antibody and Nucleic Acid Status
V. Ariyamuthu¹, R. M. LaHoz¹, N. AbdulRahim¹, S. Levea¹, M. MacConmara², C. Hwang², B. Sandikci³, B. Tanriover¹
¹Internal Medicine, UT Southwestern Medical Center, Dallas, TX, ²Surgery, UT Southwestern Medical Center, Dallas, TX, ³University of Chicago Booth School of Business, Chicago, IL
*Purpose: HCV nucleic acid testing (NAT) testing for deceased donors (DD) has been routine since 2015. We intended to look at utilization/discard rates based on…
2019 American Transplant Congress
Primary Nonfunction after Kidney Transplantation is Associated with Elevated Donor Urinary Biomarkers
S. Mohan, P. Reese, I. Hall, M. Doshi, Y. Jia, H. T. Philbrook, E. Akalin, J. Bromberg, M. Harhay, S. Mansour, T. Muthukumar, B. Schröppel, P. Singh, F. Weng, C. Parikh
for the DDS Consortium, Baltimore, MD
*Purpose: Primary nonfunction (PNF) defined as dialysis dependent for 3 months post-transplant, is a rare but catastrophic outcome for recipients. PNF also negatively impacts transplant…
2019 American Transplant Congress
Determinants of Allograft Injury during Procurement in Deceased Donors
E. Taber-Hight¹, R. Cauwels², E. Eidbo², A. S. Paramesh³, R. Squires⁴, T. Taber¹
¹Nephrology, Indiana University, Indianapolis, IN, ²AOPO, Vienna, VA, ³Louisiana Organ Procurement Agency, New Orleans, LA, ⁴University of Oklahoma, Oklahoma City, OK
*Purpose: With the ever enlarging list of potential recipients on the transplant list, the need for deceased donor organs has become critical. Avoiding injury to…
2019 American Transplant Congress
Detection and Desensitization of Donor-Specific Antibody Reduces Risk of Early but Not Late Renal Transplant Failure in a Cohort of 1000 Cases
M. Tsai, C. Lee, C. Yang, C. Chen
Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan
*Purpose: The Human Organ Transplant Act in Taiwan was promulgated in 1987 and, thereafter, organ transplantation from brain-dead donors legalized. To review the results of…
2019 American Transplant Congress
Alemtuzumab versus Anti-Thymocyte Globulin Induction in the Setting of Immediate Post-Renal Transplant Acute Tubular Necrosis in an Urban, Minority Patient Population
K. Tejani, E. Benedetti, A. Lichvar
University of Illinois at Chicago, Chicago, IL
*Purpose: Post-renal transplant (RTx) delayed graft function (DGF) or slow graft function (SGF) increase the risk of rejection and impair allograft function. Lymphocyte depleting induction…
2019 American Transplant Congress
Panel Reactive Antibody Stratification as a Guide to Induction Selection in Deceased-Donor Kidney Transplantation: Impact of Clinical Practice on Outcomes
H. Ibrahim¹, J. Gregg¹, K. Alquadan¹, U. Akanit², K. L. Womer¹, A. H. Santos¹
¹Medicine, University of Florida, Gainesville, FL, ²Ubon Ratchathani University, Ubonratchathani, Thailand
*Purpose: We aimed to determine the outcomes associated with anti-thymocyte globulin (ATG), alemtuzumab (ALM) or interleukin-2 receptor antagonist (IL2-RA) induction in adult deceased-donor (DD) kidney…
2019 American Transplant Congress
Kidney Transplantation in Patients with Neurogenic Bladder
Z. Jurekovic, M. Knotek
Clinical Hospital Merkur, 10000 Zagreb, Croatia
*Purpose: Neurogenic bladder is a condition associated with high incidence of urinary tract infections (UTI). Infections in immunocompromised patients can be life-threatening and result in…