Am J Transplant, Volume 19, Suppl 3 Archives - Page 21 of 214 - ATC Abstracts

2019 American Transplant Congress
Center-Level Probability of Kidney Transplant Varies Considerably for Waitlisted Patients
K. L. King¹, S. A. Husain¹, P. Reese², J. Schold³, S. Pastan⁴, S. Mohan¹
¹Columbia University, New York, NY, ²University of Pennsylvania, Philadelphia, PA, ³Cleveland Clinic, Cleveland, OH, ⁴Emory University, Atlanta, GA
*Purpose: Prior studies identify reducing time spent on the waitlist as a top priority for deceased donor kidney (DDK) transplant (Tx) candidates. Despite well-described geographic…
2019 American Transplant Congress
Surgical Management Of Five Hundred Patients With Chronic Gut Failure At A Single Center: Autologous Reconstruction Versus Transplantation
S. Armanyous, Y. Fouda, M. Fujiki, N. Parekh, M. Osman, R. Girlanda, K. Hashimoto, G. Costa, K. Abu-Elmagd
Cleveland Clinic, Cleveland, OH
*Purpose: To define the evolving role of autologous gut reconstruction (AGR) in the management of total parenteral nutrition (TPN)-dependent-chronic gut failure (CGF) patients with special…
2019 American Transplant Congress
Predictors of Response to Intravenous Immunoglobulin for Treatment of Polyoma Nephropathy
S. Sethi, A. Vo, A. Peng, R. Najjar, K. Lim, S. Jordan, E. Huang
Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: BK nephropathy is an important cause of allograft dysfunction or loss. IVIg is hypothesized to be effective by providing passive immunity to BK virus…
2019 American Transplant Congress
A Randomized Controlled Clinical Trial of Thymoglobulin® and Extended Delay of Calcineurin Inhibitor Therapy for Renal Protection after Liver Transplantation: A Multicenter Study
L. Coromina¹, S. Shah², B. Xervos³, M. Zimmerman⁴, K. Sasaki¹, T. Diago¹, K. Hashimoto¹, F. Aucejo¹, m. Fujiki¹, H. Block-Beach¹, A. Patterson², C. Miller¹, C. Quintini¹, B. Eghtesad¹
¹The Cleveland Clinic, Cleveland, OH, ²University of Cincinnati, Cincinnati, OH, ³The Cleveland Clinic, Weston, FL, ⁴Medical College of Wisconsin, Milwaukee, WI
*Purpose: Thymoglobulin® (r-ATG) has been used as induction therapy in liver transplantation (LT). No prospective, randomized, controlled, trial (RCT) has been performed to evaluate effect…
2019 American Transplant Congress
Impact of Recipient Age in Combined Liver-Kidney Transplantation (CLKT): Caution is Needed for Elderly Patients≥70 Years
B. Ekser¹, W. C. Goggins¹, R. S. Mangus¹, P. Mihaylov¹, J. A. Fridell¹, M. A. Lacerda², M. S. Ghabril², J. A. Powelson¹, C. A. Kubal¹
¹Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN, ²Gastroenterology, Indiana University, Indianapolis, IN
*Purpose: Recent SRTR analysis showed that elderly recipients (≥70 years) accounts for 2.6% of all liver transplant alone (LTA) and do as well as younger…
2019 American Transplant Congress
A Single Measurement of Torque Teno Virus Helps to Predict Mortality in Renal Transplant Patients
E. Gore¹, C. van Leer¹, A. de Joode², I. Nolte³, J. Westra⁴, A. Gomes Neto², H. G. Niesters¹, S. J. Bakker²
¹Department of Medical Microbiology, University Medical Centre Groningen, Groningen, Netherlands, ²Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands, ³Department of Epidemiology, University Medical Centre Groningen, Groningen, Netherlands, ⁴Department of Immunology, University Medical Centre Groningen, Groningen, Netherlands
*Purpose: Multiple studies have used longitudinal Torque Teno Virus (TTV) measurements to assess the immune status after transplantation. Longitudinal measurements generally show a TTV load…
2019 American Transplant Congress
MDSCs Prolong Allogeneic Cardiac Graft Survival by Regulating Interferon Type 1 Signaling
S. Cai¹, P. T. Sage¹, T. J. Borges¹, T. Ichimura¹, S. K. Eskandari¹, J. Y. Choi¹, I. Salkuj¹, B. S. AI Dulaijan¹, H. Allos¹, J. Miao², L. V. Riella¹, A. K. Chandraker¹, J. R. Azzi¹
¹Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Boston Children's Hospital, Harvard Medical School, Boston, MA
*Purpose: We previously demonstrated that donor-derived regulatory dendritic cells (DCreg), contrary to recipient derived DCreg, promote antigen-specific allograft protection. As myeloid-derived suppressor cells (MDSC) show…
2019 American Transplant Congress
Racial and Ethnic Disparities in Access to Living Donor Kidney Transplantation in the US: Have We Made Any Progress among Pediatric Candidates over the Last Twenty Years?
T. Purnell¹, S. Bae¹, X. Luo¹, A. Chen¹, D. Crews¹, L. Cooper¹, O. N. Bignall II², K. Covarrubias¹, D. Segev¹
¹Johns Hopkins School of Medicine, Baltimore, MD, ²Nationwide Children’s Hospital, Columbus, OH
*Purpose: A recent JAMA study demonstrated worsening disparities in access to living donor kidney transplantation (LDKT) among adults in the US. We examined twenty-year trends…
2019 American Transplant Congress
Alloreactive B Cells in Transplant Tolerant Recipients Cannot Differentiate into Antibody-Secreting Cells but Can Suppress Donor-Specific IgG Production By Naïve B Cells
S. H. Khiew¹, J. Chen¹, D. Jain¹, Q. Wang¹, D. Yin¹, M. Alegre², A. S. Chong¹
¹Department of Surgery, Section of Transplant, University of Chicago, Chicago, IL, ²Department of Medicine, University of Chicago, Chicago, IL
*Purpose: Donor specific transplantation tolerance has long been the goal of clinical transplantation. Clinical observations suggest that donor-specific antibodies (DSA) are a major cause of…
2019 American Transplant Congress
Exosomes Isolated from Human Lung Transplant Recipients Diagnosed with Bronchiolitis obliterans Syndrome are Unique in Their Ability to Induce IL-6 via Rab27A Signaling Pathway
M. Rahman, M. Sharma, S. Angara, M. Smith, R. Bremner, T. Mohanakumar
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Rab27, a member of the Rab subfamily of GTPases, has the ability to induce exosome secretion. Exosomes are small membrane vesicles (40-150nm) that regulate…