Am J Transplant, Volume 19, Suppl 3 Archives - Page 205 of 214 - ATC Abstracts

2019 American Transplant Congress
Circulating Exosomes Isolated from Human Lung Transplant Recipients with Respiratory Viral Infections Contain Nucleic Acids Specific to Virus and Can Lead to Activation of Stress Proteins
S. Bansal, R. Bremner, M. Smith, T. Mohanakumar
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Exosomes are membrane vesicles released by cells into body fluids. Our laboratory demonstrated the presence of circulating exosomes with lung self-antigens (SAgs), Collagen V…
2019 American Transplant Congress
Outcomes after Simultaneous Kidney Pancreas versus Pancreas after Kidney Transplantation
S. Parajuli, A. Arunachalam, K. Swanson, F. Aziz, N. Garg, R. Redfield, D. Kaufman, A. Djamali, J. Odorico, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: Simultaneous pancreas and kidney (SPK) or pancreas after kidney (PAK) transplant are potential options for diabetic ESRD patients. Historically, PAK pancreas graft outcomes were…
2019 American Transplant Congress
Non-Immunologic Donor-Recipient Pairing, HLA Matching, and Graft Loss in Deceased Donor Kidney Transplantation
A. Vinson¹, B. Kiberd¹, R. Davis², K. Tennankore¹
¹Dalhousie University, Halifax, NS, Canada, ²Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
*Purpose: In kidney transplantation, non-immunologic donor-recipient (D-R) pairing is generally not given the same consideration as immunologic matching. The aim of this study was to…
2019 American Transplant Congress
MELD Score and Anti-Angiotensin Receptor Antibody Predict Long-Term Survival of Liver Re-Transplant
Q. Xu¹, A. Skaro², V. C. McAlister²
¹Pathology and Lab Medicine, London Health Science Center, London, ON, Canada, ²Surgery, London Health Science Center, London, ON, Canada
*Purpose: Recent reports indicated important while inconsistent roles of preformed donor specific antibody (DSA) to HLA in liver transplantation. Re-transplant liver patients were understudied due…
2019 American Transplant Congress
5,000 Living Donor Liver Transplantations
G. Song, S. Lee, S. Hwang, K. Kim, C. Ahn, D. Moon, T. Ha, D. Jung, G. Park, Y. Yoon, J. Kwon, H. Cho, Y. Jung, S. Kang, I. Jeong, J. Choi
Division of LT and HBB Surgery, Department of Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea, Republic of
*Purpose: To review single center's experiences in living donor liver transplantation (LDLT) and analyze risk factors affecting short and long-term outcomes.*Methods: Retrospective analysis of 5,000…
2019 American Transplant Congress
Differences in CMV-Specific CD4 T Cell Population in De Novo Kidney Transplant Recipients Treated with Everolimus-Based Regimen Compared to a Standard Tacrolimus-MPA Regimen: Results from ATHENA
I. A. Hauser¹, S. Marx¹, C. Sommerer¹, B. Suwelack¹, D. Dragun¹, O. Witzke¹, F. Lehner¹, I. Kroeger², M. Junge², F. Thaiss¹, B. Nashan¹, M. Sester¹
¹ATHENA, CMV Substudy Group, Germany, ²Novartis, Pharma GmbH, Germany
*Purpose: The ATHENA trial was designed to compare everolimus [EVR] in combination with tacrolimus [TAC] or cyclosporine A [CyA] vs. a standard regimen of mycophenolic…
2019 American Transplant Congress
Complement Blockade in Kidney Recipients Prevents Delayed Graft Function and Antibody-Mediated Rejection in Non-Human Primates
M. Eerhart¹, J. Reyes¹, C. Blanton¹, J. Danobeitia¹, P. Chlebeck¹, L. Zitur¹, J. Coonen¹, S. Capuano¹, A. D’Alessandro¹, J. Torrealba², W. Zhong¹, Y. Yankol¹, L. Fernandez¹
¹University of Wisconsin, Madison, WI, ²UT Southwestern, Dallas, TX
*Purpose: Ischemia-reperfusion injury (IRI) leading to inflammation, complement activation, cytokine release and acute kidney injury has been implicated in the mechanism for delayed graft function…
2019 American Transplant Congress
Clinical Implications of Serum Mac-2 Binding Protein in Regular Follow Up after Pediatric Living Donor Liver Transplantation
T. Ueno¹, T. Kodama¹, Y. Noguchi¹, M. Nomura¹, R. Saka¹, Y. Takama¹, Y. Tazuke¹, K. Bessho², H. Okuyama¹
¹Pediatric Surgery, Osaka University Graduate School of Medicine, Suita, Japan, ²Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan
*Purpose: Pediatric living donor liver transplant (LDLT) patients sometimes develops graft fibrosis. They showed graft fibrosis even if their liver function tests were within normal…
2019 American Transplant Congress
The Role of the T Regulatory Cell Compartment in Intestinal Transplant Patients: Helpful or Unhinged?
L. Belyayev¹, M. Sadat², K. Loh³, S. Moturi², K. Khan², J. Hawksworth², C. Matsumoto², T. M. Fishbein², A. Kroemer²
¹Surgery, Walter Reed National Military Medical Center, Bethesda, MD, ²Transplant, MedStar Georgetown Transplant Institute, Washington D.C., DC, ³Pediatrics, Children’s National Medical Center, Washington D.C., DC
*Purpose: The T regulatory (Treg) cell compartment has now been established as a key player in dampening T helper 17 (Th17) mediated inflammation, managing self-tolerance,…
2019 American Transplant Congress
Donor-Derived Cell-Free DNA in Urine Identifies BKVN with Graft Injury in BK Viruria Kidney Transplant Recipients
G. Huang¹, X. Chen¹, S. Yang², W. Chen², P. Chen³, X. Hou⁴, T. Jiang⁵, H. Liu⁵, X. Li⁵, C. Wang¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ³Department of clinical laboratory, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ⁴Guangzhou KingMed Center for Clinical Laboratory Co.,Ltd., Guangzhou, China, ⁵Research and Development, AlloDx Biotech Co.Ltd., Suzhou, China
*Purpose: BK Polyomavirus nephropathy (BKVN) is an important cause of dysfunction and failure of renal transplants. Elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the…