Am J Transplant, Volume 19, Suppl 3 Archives - Page 203 of 214 - ATC Abstracts

2019 American Transplant Congress
Gut Dysbiosis Predominates Post-Transplant Diarrhea in Kidney Transplant Recipients: A Validation Study
L. Zhang, J. Lee, M. Magruder, E. Edusei, D. Dadhania, M. Lubetzky, S. Albakry, B. Botticelli, E. Pamer, M. Suthanthiran
Weill Cornell Medicine, New York, NY
*Purpose: Lower abundance of commensal bacterial taxa in the gut has been previously described in a recent study of kidney transplant recipients with post-transplant diarrhea…
2019 American Transplant Congress
Occult Liver Graft Fibrosis Prior to Transplantation Influences Clinical Outcomes
H. Hirao, T. Ito, K. Kadono, S. Kageyama, K. Nakamura, K. J. Dery, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski
Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Liver transplantation (LT) has become a standard therapy for the management of end-stage liver disease, while early allograft dysfunction (EAD) remains a serious problem.…
2019 American Transplant Congress
A Clinical Pharmacogenetic Model to Predict the Efficacy of Sirolimus during the Early Administration in Renal Transplant Recipients
Z. Wang, S. Fei, Z. Han, J. Tao, R. Tan, M. Gu
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: This study was to develop a clinical pharmacogenetic model to predict the efficacy of sirolimus during the early administration in renal transplant recipients. 70…
2019 American Transplant Congress
The Economic Burden of Graft Failure in the United States
J. A. Sussell¹, A. R. Silverstein¹, P. Goutam¹, D. Incerti¹, R. Kee¹, D. S. Batty, Jr.², C. X. Chen², J. Jansen¹, B. L. Kasiske³
¹Precision Health Economics, Oakland, CA, ²Medeor Therapeutics, South San Francisco, CA, ³Hennepin County Medical Center, Minneapolis, MN
*Purpose: Despite recent advances, graft failure imposes a substantial burden on kidney transplant recipients. This study is the first to quantify this burden in economic…
2019 American Transplant Congress
Urinary Injury Biomarkers in Deceased Donors and Acute Rejection Post Kidney Transplant
P. Reese¹, I. Hall², S. Mohan³, H. Theissen-Philbrook⁴, Y. Jia⁴, M. Doshi⁵, J. Bromberg⁶, S. Mansour⁷, M. Harhay⁸, F. Weng⁹, E. Akalin¹⁰, C. Parikh⁴
¹UPENN, Philadelphia, PA, ²Univ of Utah, Salt Lake City, UT, ³Columbia, NY, NY, ⁴Johns Hopkins, Baltimore, MD, ⁵Univ of Michigan, Ann Arbor, MI, ⁶Univ of Maryland, Baltimore, MD, ⁷Yale, New Haven, CT, ⁸Drexel, Philadelphia, PA, ⁹St. Barnabas, Philadelphia, PA, ¹⁰Montefiore, NY, NY
*Purpose: Acute kidney injury (AKI) is common among deceased kidney donors. We hypothesized that inflammation from kidney injury could lead to enhanced expression of HLA…
2019 American Transplant Congress
Earlier Transplant Education as CKD Progresses? CKD 3-5 Patients and Providers Weigh In
A. D. Waterman¹, O. N. Ranasinghe¹, A. F. Lipsey², C. S. Anderson¹, A. Alem³, C. Bozzolo⁴, B. Dub³, S. L. Henry³, B. Mittman³
¹Division of Nephrology, UCLA School of Medicine, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, ⁴Insight Policy Research, Arlington, VA
*Purpose: To increase preemptive and early transplant rates, transplant education must be delivered along the entire chronic kidney disease (CKD) spectrum. To understand patients’ education…
2019 American Transplant Congress
Evolution of HHV6- and CMV-Specific T Cell Functional Responses and Immune Cell Populations after Kidney Transplant
A. Gil¹, M. Co², M. Calvo-Calle¹, J. Cruz¹, L. Stern¹, L. Gibson²
¹Pathology, University of Massachusetts Medical School, Worcester, MA, ²Medicine, University of Massachusetts Medical School, Worcester, MA
*Purpose: Human herpesvirus (HHV)-6 reactivation after solid organ or hematopoietic stem cell transplant has been associated with complications such as graft rejection and all-cause mortality.…
2019 American Transplant Congress
The Increasing Financial Challenge of Liver Transplantation
D. Axelrod¹, S. Hohmann², K. Lentine³, H. Xiao³, B. Kasiske⁴, J. Snyder⁴, M. Ostrander⁵, M. Schnitzler³
¹Univ of Iowa, Iowa City, IA, ²Vizient Inc, Chicago, IL, ³Saint Louis Univ, St. Louis, MO, ⁴SRTR, Minneapolis, MN, ⁵Visient, Inc., Minneapolis, IA
*Purpose: Despite innovations in clinical care, liver transplant (LT) remains highly resource intensive due to medical complexity and organ quality. National allocation systems prioritize access…
2019 American Transplant Congress
p40 Homodimer Indirectly Induce Proliferation of Endogenous Donor-Reactive Memory CD8 T Cells within High-Risk Allografts via IL-15 Signaling
H. Tsuda, A. Valujskikh, R. Fairchild
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Increasing the duration of cold ischemic storage (CIS) from 0.5 to 8 hrs prior to transplant induces the increased proliferation of endogenous donor-reactive CD4…
2019 American Transplant Congress
The End of Non-Directed Living Kidney Donation: The National Kidney Registry’s Family Voucher Program
M. Cooper¹, D. Leeser², S. Flechner³, J. Verbesey¹, M. Ronin⁴, G. Hil⁴, A. Waterman⁵, J. Veale⁵
¹Georgetown Transplant Institute, Washington, DC, ²East Carolina University, Greenville, NC, ³Cleveland Clinic, Cleveland, OH, ⁴National Kidney Registry, New York, NY, ⁵UCLA, Los Angeles, CA
*Purpose: The continued growth of the National Kidney Registry’s (NKR) Voucher program has extended Kidney Paired Donation (KPD) to include chronological incompatibility which is facilitating…