Am J Transplant, Volume 19, Suppl 3 Archives - Page 2 of 214 - ATC Abstracts

2019 American Transplant Congress
Mismatched Epitope and De Novo DSA Development: An Analysis of the Benefit and Benefit-EXT Renal Transplant Cohorts
V. Jucaud¹, V. Burnett¹, H. Gebel², R. Bray², M. Polinsky³, M. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Emory University, Atlanta, GA, ³Bristol-Myers Squibb, Princeton, NJ
*Purpose: De novo donor-specific HLA antibodies (dnDSA) target epitopes rather than whole antigens, and their development is associated with the mismatched HLA antibody epitope load…
2019 American Transplant Congress
Vaccination Rates and Relation to Health Beliefs in Inner-City Kidney Transplant Recipients (KTRs)
Y. Akivis, J. Leong, I. Rosenstein, A. Myrie, M. Moy, M. Markell
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Prophylaxis against viral and bacterial infections as outlined by guidelines issued by the 2013 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for…
2019 American Transplant Congress
Center Variability in Organ Offer Acceptance and Waitlist Mortality in Lung Transplantation
A. Y. Choi¹, M. S. Mulvihill², J. Weber³, H. Lee³, M. Cox², B. Yerokun², M. Kuchibhatla³, J. A. Klapper², M. G. Hartwig²
¹Duke University School of Medicine, Durham, NC, ²Department of Surgery, Duke University Medical Center, Durham, NC, ³Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC
*Purpose: Lung transplantation (LTx) offers a survival benefit for patients with end-stage lung disease. When suitable donors are identified, centers must accept or decline the…
2019 American Transplant Congress
Humoral Immune Responses to Kidney Associated Non-HLA Antigens is Not Associated with Progression to Chronic Immune Injury in Kidney Transplant Recipients
S. Sukumaran Nair¹, R. Ravichandran², R. Heilman¹, A. Jaramillo¹, D. Ramon¹, M. Buras¹, B. Kaplan¹, T. Mohanakumar²
¹Mayo Clinic, Phoenix, AZ, ²St. Joseph’s Hospital, Phoenix, AZ
*Purpose: Development of donor specific anti-HLA (DSA) although is a known risk factor for Chronic immune injury (CII), it is undetectable in many patients with…
2019 American Transplant Congress
Kidney Donor Outcomes ≥ 50 Years Post Donation
D. Keys, S. Jackson, A. Matas
University of Minnesota, Minneapolis, MN
*Purpose: Data on true long-term follow-up (LTFU) of living kidney donors (LD) is sparse. Given this, the acceptance of young donors can be a challenging…
2019 American Transplant Congress
Patient-Reported Outcomes in a Prospective Multicenter Trial of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression Regimens in Kidney Transplantation
J. M. Rohan¹, J. P. Leone², E. S. Woodle³, D. Kaufman⁴, A. R. Shields³, A. Wiseman⁵, A. J. Matas⁶, P. West-Thielke⁷, E. King³, R. R. Alloway³
¹Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, ²Tampa General Hospital, Tampa, FL, ³University of Cincinnati College of Medicine, Cincinnati, OH, ⁴University of Wisconsin – Madison, Madison, WI, ⁵University of Colorado - Denver, Denver, CO, ⁶University of Minnesota Medical Center, Minneapolis, MN, ⁷University of Illinois – Chicago, Chicago, IL
*Purpose: Previous trials have not examined differences in patient-reported outcomes (PRO) between belatacept (BELA)- and tacrolimus (TAC)-based therapies in adult kidney transplant (KTx) patients (pts).…
2019 American Transplant Congress
The Frequency of Tissue-Resident Donor T and NK Cells in Peripheral Blood after Lung Transplantation is Modulated by Normothermic Ex Vivo Lung Perfusion
C. S. Falk¹, B. Wiegmann², A. Hitz¹, R. Bellmas-Sanz¹, K. Bläsing¹, F. Ius², C. Kühn², M. Avsar², I. Tudorache², J. Kühne¹, F. Wandrer¹, A. Haverich², G. Warnecke²
¹Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
*Purpose: The appearance of passenger donor lymphocytes in recipient blood after double lung transplantation has been described decades ago. However, neither their early kinetics, nor…
2019 American Transplant Congress
Newly-Revealed Antibody Targets Lead to the Early Loss of Triple Knockout Pig Kidneys in a Pig to Baboon Model
Y. Ariyoshi¹, K. Takeuchi¹, T. Pomposelli¹, D. K. Ekanayake-Alper¹, C. Schuetz¹, H. Sahara¹, L. Boyd¹, E. Estime¹, S. Arn¹, D. Ayares², M. Lorber³, M. Sykes¹, D. Sachs¹, K. Yamada¹
¹CCTI/Surgery, Columbia University Medical Center, New York, NY, ²Revivicor Inc., Blacksburg, VA, ³Lung BioTechnology PBC, Silver Spring, MD
*Purpose: We have achieved >6 months survival of a life-supporting kidney with a vascularized thymus (VT) in a pig-to-baboon model. While improved survival has been…
2019 American Transplant Congress
Simulated Tier Variability
N. Salkowski, A. Wey, J. Snyder
SRTR, Minneapolis, MN
*Purpose: The Scientific Registry of Transplant Recipients semi-annually assigns transplant programs to one of five performance tiers for 1-year graft survival in its program-specific reports…
2019 American Transplant Congress
Adipose Stem Cells Promote Composite Tissue Engraftment
N. Shockcor¹, B. Buckingham¹, W. Hassanein¹, D. Parsell¹, U. Dhru¹, B. Akinsiku², E. Elster², T. Davis², J. Gimble³, A. Nam¹, S. Bartlett¹, R. Barth¹
¹Surgery, University of Maryland, Baltimore, MD, ²Uniformed Services University of the Health Sciences, Bethesda, MD, ³LaCell LLC, New Orleans, LA
*Purpose: Adipose-derived stem cells (ASC) have increased levels of anti-inflammatory and immunoregulatory factors. Murine studies have shown stable macrochimerism and long-term full thickness skin graft…