Am J Transplant, Volume 19, Suppl 3 Archives - Page 195 of 214 - ATC Abstracts

2019 American Transplant Congress
Successful Weaning Of Parenteral Nutrition After Serial Transverse Enteroplasty: The Largest Series Of Adult Short Gut Syndrome Patients
M. Fujiki, S. Armanyous, K. Abu-Elmagd
Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Serial Transverse Enteroplasty Procedure (STEP) is an effective procedure to restore nutritional autonomy, but with limited experience especially in adult patients. The aims of…
2019 American Transplant Congress
Deceased-Donor Acute Kidney Injury Associates with Less BK Viremia in Kidney Transplant Recipients
I. E. Hall, P. P. Reese, S. G. Mansour, S. Mohan, M. D. Doshi, Y. Jia, H. R. Thiessen-Philbrook, E. Akalin, M. N. Harhay, T. Muthukumar, B. Schröppel, P. Singh, F. L. Weng, J. S. Bromberg, C. R. Parikh
For the DDS Consortium, Baltimore, MD
*Purpose: BK viremia (BKV) and polyomavirus nephropathy are kidney transplant complications that contribute to morbidity and graft loss, and prior studies suggest they may be…
2019 American Transplant Congress
Estimated Glomerular Filtration Rate at Donor Screening to Predict Measured Glomerular Filtration Rate after Living Kidney Donation
J. van der Weijden, M. van Londen, M. Y. Said, S. J. Bakker, S. P. Berger, G. Navis, M. H. de Borst
Nephrology, University Medical Center Groningen, Groningen, Netherlands
*Purpose: Accurate post-donation renal function prediction is important to minimize the risk of future severe renal function impairment in living kidney donors. Recent studies focused…
2019 American Transplant Congress
Is Alemtuzumab Induction Safe In Septuagenarians Undergoing Deceased Donor Kidney Transplantation?
D. Harriman, V. Gurram, C. Jay, J. Rogers, A. Farney, G. Orlando, A. Reeves-Daniel, A. Mena-Gutierrez, R. Stratta
Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: Alemtuzumab induction in septuagenarians is controversial but understudied.*Methods: Single center retrospective review of adult deceased donor kidney transplant (KT) recipients receiving single dose (30…
2019 American Transplant Congress
Promotion of Chimerism by Lymphohematopoietic Graft-versus-Host Responses in Patients Receiving Intestinal Transplantation
J. Fu¹, J. Zuber¹, B. Shonts¹, A. Obradovic¹, K. Frangaj¹, E. E. Waffarn¹, S. Lau¹, T. M. Savage¹, S. Yang¹, K. Rogers¹, P. Satwani², S. Ho¹, Y. Shen³, A. Griesemer⁴, M. Martinez², T. Kato⁴, M. Sykes¹
¹Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Department of Systems Biology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Long-term multilineage chimerism often appears in blood following intestinal transplantation (ITx), usually without graft-versus-host disease (GVHD). Patients with donor T cell macrochimerism (≥4%) in…
2019 American Transplant Congress
Engineering Regulatory T Cells With TCR-Signaling-Responsive Interleukin 2 Nanoparticles Provides In Situ Suppression Of Alloimmunity
S. K. Eskandari¹, M. B. Melo², I. Sulkaj¹, N. Li², S. Cai¹, H. Allos¹, J. Y. Choi¹, D. J. Irvine², J. R. Azzi¹
¹Harvard Medical School, Brigham and Women's Hospital, Boston, MA, ²David H. Koch Institute for Integrative Cancer Research, Cambridge, MA
*Purpose: Adoptive cell transfer of regulatory T cells (TReg) has shown great potential in animal models of auto- and alloimmunity. The translation of TReg therapies…
2019 American Transplant Congress
Development of a Pharmacy Collaborative Practice Agreement to Improve Efficiency and Management of Prescribing in a Renal Transplant Clinic
R. Chelewski¹, K. Johnson¹, A. Zuckerman², J. DeClercq³, L. Choi³, M. Peter², A. J. Langone⁴
¹Vanderbilt Specialty Pharmacy Services, Vanderbilt Univ Medical Ctr, Nashville, TN, ²Department of Pharmacy, Vanderbilt Univ Medical Ctr, Nashville, TN, ³Department of Biostatistics, Vanderbilt Univ Medical Ctr, Nashville, TN, ⁴Division of Nephrology, Vanderbilt Univ Medical Ctr, Nashville, TN
*Purpose: This study describes the development of a Collaborative Pharmacy Practice Agreement (CPPA) between transplant pharmacists and physicians and assesses change in prescription volume and…
2019 American Transplant Congress
Three-Year Outcomes of Highly-Sensitized Kidney Transplant Recipients Desensitized with Imlifidase (IdeS)
E. Huang¹, J. Choi¹, A. Vo¹, A. Peng¹, R. Najjar¹, S. Sethi¹, C. Kjellman², L. Winstedt², N. Ammerman¹, S. C. Jordan¹
¹Cedars Sinai Medical Center, Los Angeles, CA, ²Hansa Medical, Lund, Sweden
*Purpose: The HLA-incompatible (HLAi) barrier has been traversed using desensitization therapies with IVIg, rituximab and/or plasmapheresis, although antibody-mediated rejection (ABMR) continues to be observed in…
2019 American Transplant Congress
Effect of Chronic Kidney Disease on Allo-Immune Response in Mice
P. D. Winterberg¹, H. Li¹, M. E. Wagener², M. L. Ford²
¹Pediatrics, Emory University School of Medicine, Atlanta, GA, ²Surgery, Emory University School of Medicine, Atlanta, GA
*Purpose: Accumulation of memory T cells bearing markers of sustained antigen stimulation have been described in patients with chronic kidney disease (CKD). However, mouse models…
2019 American Transplant Congress
Clonal Composition And Single-cell Characterization Of T-cell Infiltrates In Cardiac Allograft Vasculopathy
M. V. Habal¹, A. Myung², H. Yan², S. Rao², S. Lin², S. See², P. Roy², R. Shihab², C. Marboe³, S. Restaino¹, A. Han², M. Givertz⁴, J. C. Madsen⁵, L. Addonizio¹, M. Farr¹, E. Zorn²
¹Cardiology, Columbia University Medical Center, New York, NY, ²Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY, ³Pathology, Columbia University Medical Center, New York, NY, ⁴Cardiology, Brigham and Women's Hospital, Boston, MA, ⁵Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: T-cells are implicated in the pathogenesis of cardiac allograft vasculopathy (CAV), yet their clonal composition and function are incompletely defined. We examined the T-cell…