ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Monitoring And Management Of Proteinuria Is Often Ignored In Patients Receiving mTOR Therapy Following Orthotopic Liver Transplantation

    R. Kaur1, O. Sadiq2, M. Alimirah1, F. Kumssa1, A. Patel3, S. Jafri2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI, 2Gastroenterology, Henry Ford Hospital, Detroit, MI, 3Nephrology, Henry Ford Hospital, Detroit, MI

    *Purpose: Use of mTOR inhibitors, such as Everolimus (EVL), in liver transplant (LT) patients continues to rise as the side effect profile becomes more evident.…
  • 2019 American Transplant Congress

    Is Bariatric Surgery Feasible in the Setting of Liver and Kidney Transplants?

    L. M. Potter, A. Saharia, C. Mobley, K. Lunsford, M. Hobeika, N. Tariq, H. Podder, A. O. Gaber, R. M. Ghobrial

    Liver Transplant and Hepatobiliary Surgery, The Houston Methodist Hospital, Houston, TX

    *Purpose: Bariatric surgery benefits obese patients by promoting weight loss, improving quality of life, and reducing morbidity and mortality rates. There is concern, however, that…
  • 2019 American Transplant Congress

    The Liver Frailty Index is Associated with Current and Subsequent Disability in Liver Transplant Candidates

    J. C. Lai, J. L. Dodge, C. E. McCulloch, K. E. Covinsky, J. P. Singer

    University of California, San Francisco, San Francisco, CA

    *Purpose: The Liver Frailty Index (LFI) was developed to capture the effects of malnutrition and muscle wasting in patients with cirrhosis awaiting liver transplantation (LT).…
  • 2019 American Transplant Congress

    Impact of Multidrug-Resistant Organisms among Donors on Organ Utilization

    J. A. Anesi1, E. Lautenbach1, J. H. Han1, D. H. Lee2, H. Clauss3, A. Climaco4, R. Hasz5, E. Molnar3, D. Alimenti1, S. West5, W. B. Bilker1, P. Tolomeo1, E. A. Blumberg1

    1University of Pennsylvania, Philadelphia, PA, 2Drexel University College of Medicine, Philadelphia, PA, 3Temple University, Philadelphia, PA, 4Albert Einstein Medical Center, Philadelphia, PA, 5Gift of Life Donor Program, Philadelphia, PA

    *Purpose: Though transplant guidelines recommend exercising caution when considering donor organs that may be infected or colonized with multidrug-resistant organisms (MDROs), the true impact of…
  • 2019 American Transplant Congress

    Comparison of Proton Pump Inhibitors versus Histamine-2-Receptor Antagonists on Clostridium difficile Rates in Liver Transplant Recipients

    S. Wiehe, K. Roach, A. Qamar

    Lahey Hospital and Medical Center, Burlington, MA

    *Purpose: To determine if there is a difference in 90 day Clostridium difficile infection (CDI) rates before and after the stress ulcer prophylaxis (SUP) protocol…
  • 2019 American Transplant Congress

    The Economic Impact of Surgical Site Infections in Liver Transplantation

    Y. Natori1, D. Kumar2, A. Humar2, S. Husain2, C. Rotstein3

    1Miami Transplant Institute, University of Miami, Miami, FL, 2Transplant Infectious Diseases, University of Toronto, Toronto, ON, Canada, 3University of Toronto, Toronto, ON, Canada

    *Purpose: Complications arising after liver transplantation result in additional healthcare costs. Previous studies have not evaluated the impact of surgical site infections on healthcare costs…
  • 2019 American Transplant Congress

    Inhibition of TLR4 Mediated Programmed Necrosis Does Not Improve Graft Function and Histology in a Murine Kidney Transplant Model

    S. Jain1, R. Plenter2, T. Nydam2, A. Jani1

    1Renal Division, University of Colorado, Aurora, CO, 2Transplant Microsurgery Program, University of Colorado, Aurora, CO

    *Purpose: Human Delayed Graft Function (DGF) is associated with upregulation of basolateral tubular TLR4 but whether TLR4 causes DGF is unknown. TLR4 has been shown…
  • 2019 American Transplant Congress

    Ischemia-Free Liver Transplantation Protects Bile Duct from Ischemia/Reperfusion Injury

    J. Yang, S. Huang, Z. Zhang, Q. Zhao, W. Ju, Z. Zhu, Y. Tang, L. Wang, Y. Zhang, C. Sun, L. Wu, Z. Guo, X. He

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    *Purpose: Ischemia-free liver transplantation (IFLT), based on normothermic machine perfusion and innovations in surgical technique, can provide continue blood supply from procurement to implantation that…
  • 2019 American Transplant Congress

    The Negative Costimulatory Pd-1/pd-l1 Pathway Is Upregulated In Early Cell-mediated Rejection

    T. Kurashige, R. Khedraki, K. Keslar, N. Dvorina, W. Baldwin

    Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH

    *Purpose: Extensive transcript analysis has been performed on grafts at the time of rejection, but gene expression preceding overt rejection is less well studied.*Methods: We…
  • 2019 American Transplant Congress

    Metabolomic Study Of Sarcopenia In Patients Prior To Liver Transplantation

    S. Ries,1, N. J. Skill1, E. Campbell1, R. Daniel2, C. A. Kubal1, M. S. Richard1, M. A. Maluccio1

    1Surgery, Indiana University, Indianapolis, IN, 2University of Washington, Seattle, WA

    *Purpose: Sarcopenia is defined as the loss of muscle mass, typically associated with aging, but frequently appearing in liver disease patients. In particular, sarcopenia present…
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