ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Changes in Kidney Function Following Live Donor Nephrectomy

    N. N. Lam1, A. Lloyd1, K. L. Lentine2, R. R. Quinn3, B. R. Hemmelgarn3, S. Klarenbach1, A. X. Garg4

    1University of Alberta, Edmonton, AB, Canada, 2Saint Louis University, St. Louis, LA, 3University of Calgary, Calgary, AB, Canada, 4Western University, London, ON, Canada

    *Purpose: Understanding the decline in kidney function after live donor nephrectomy can inform the counselling and selection of donor candidates and guide the follow-up care…
  • 2019 American Transplant Congress

    Predicting Transplant Rejection by a Composite Urinary Injury Score

    J. Y. Yang, R. Sarwal, T. K. Sigdel, M. M. Sarwal

    Department of Surgery, UCSF, San Francisco, CA

    *Purpose: While sequencing or SNP-based methods of quantifying donor-derived cell-free DNA (dd-cfDNA) from plasma have been used to detect allograft rejection, they remain expensive and…
  • 2019 American Transplant Congress

    Absence of Protective Innate Lymphoid Cell Type 3 (ILC3) and Persistence of Proinflammatory Innate Lymphoid Cell Subsets Immediately Post-Transplant Plays a Appreciable Role in Early Intestinal Barrier Dysfunction

    J. Kang, L. Belyayev, K. Loh, P. Cha, S. Moturi, K. Khan, J. Hawksworth, C. Matsumoto, M. Zasloff, T. Fishbein, A. Kroemer

    Georgetown University, Washington, DC

    *Purpose: Innate lymphoid cells (ILCs) , the most recently described family of lymphoid cells, play fundamental roles in mucosal barrier immunity, tissue homeostasis, and immune…
  • 2019 American Transplant Congress

    Assessment of the Global Practice of Pediatric Living Donor Liver Transplantation: Comparison of U.S. and International Programs

    J. Emamaullee1, M. Kim1, C. Conrad1, C. Lane1, P. Singh1, C. Niemann2, L. Sher1, Y. Genyk1

    1University of Southern California, Los Angeles, CA, 2University of California-San Francisco, San Francisco, CA

    *Purpose: As programs have become more experienced with living donor liver transplantation (LDLT), technical hurdles have been overcome and superior graft and patient survival has…
  • 2019 American Transplant Congress

    Social Loafing: Distribution of Kidneys with Multiple Renal Arteries in a National Paired Kidney Exchange Program

    G. R. Roll1, W. Irish2, M. Cooper3, M. Ronin4, G. Hil4, A. D. Waterman5, D. B. Leeser2

    1UCSF, San Francisco, CA, 2ECU, Greenville, NC, 3Georgetown Univ, Washington, DC, 4NKR, Babylon, NY, 5UCLA and Terasaki Research Institute, Los Angeles, CA

    *Purpose: To describe the distribution and outcomes after kidney transplantation of multiple renal artery kidneys (MRAK) in a national exchange program.*Methods: We retrospectively reviewed donor…
  • 2019 American Transplant Congress

    Impact Of Subclinical Bk Virus-associated Nephropathy In High-risk Recipients

    M. E. Seifert, E. P. Kasik, M. Bernard, G. Agarwal, H. Fatima, R. Gaston, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, F. Rosenblum, G. Towns, R. B. Mannon

    University of Alabama, Birmingham, AL

    *Purpose: BK virus-associated nephropathy (BKVAN) is a major contributor to kidney transplant failure. Surveillance of serum and urine for the BKV genome has been incorporated…
  • 2019 American Transplant Congress

    Kidney Evaluation in Living Kidney Donors: Survey of US Transplant Centers 2018

    N. Garg1, K. L. Lentine2, L. Inker3, A. X. Garg4, J. Rodrigue5, D. Segev6, D. A. Mandelbrot1

    1UW Madison, Madison, WI, 2SLU, St. Louis, MO, 3Tufts, Boston, MA, 4Western University, London, ON, Canada, 5BIDMC, Boston, MA, 6JHU, Baltimore, MD

    *Purpose: In recent years, a great deal of new data has emerged on outcomes after living donation. We surveyed US transplant centers to assess current…
  • 2019 American Transplant Congress

    Age-Related Effects on Thymic Output and Homeostatic T Cell Expansion Following Depletional Induction

    H. Xu, H. Lee, A. Kirk

    Surgery, Duke University, Durham, NC

    *Purpose: Alemtuzumab induction leads to profound T cell depletion followed by a prolonged period of repopulation. Repopulation is thought to be influenced both by thymic…
  • 2019 American Transplant Congress

    Pre-Transplant Transcriptomic Signature in Peripheral Blood Predicts Early Acute Rejection after Kidney Transplant

    W. Zhang1, Z. Yi1, C. Wei1, K. Keung2, Z. Sun1, C. Xi1, C. Woytovich1, S. Farouk1, L. Gallon3, M. Menon1, C. Magee4, N. Najafian4, M. Samaniego5, A. Djamali6, S. Alexander2, I. Rosales7, R. Smith7, P. O'Connell2, R. Colvin7, P. Cravedi1, B. Murphy1

    1Icahn School of Medicine at Mount Sinai, New York, NY, 2The University of Sydney, Sydney, Australia, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Brigham and Women's Hospital, Boston, MA, 5Henry Ford Hospital, Detroit, MI, 6University of Wisconsin, Madison, WI, 7Massachusetts General Hospital, Boston, MA

    *Purpose: Early development of acute rejection after kidney transplantation is associated with diminished long-term graft survival. Predicting early acute rejection (EAR) at the time of…
  • 2019 American Transplant Congress

    Differences of Gut Microbiota Composition between Donor and Recipient May Predict 1-Year Graft Function

    J. Kim1, H. Cho2, J. Park3, J. Jeong1, M. Kwak4, B. Kim4, D. Kim1, J. Lee5, B. Kim6, Y. Kim1, H. Lee1

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Chungbuk National University Hospital, Cheongju, Korea, Republic of, 3Kangwon National University Hospital, Seoul, Korea, Republic of, 4Chunlab Inc., Seoul, Korea, Republic of, 5Seoul National University Boramae Hospital, Seoul, Korea, Republic of, 6Hallym University, Chuncheon, Korea, Republic of

    *Purpose: Signals derived from gut microbiota are critical for the development and maintenance of the human immune system. In view of kidney transplantation (KT), allograft…
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