ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Adult Living Donor vs. Deceased Donor Liver Transplant (LDLT vs. DDLT) at a Single US Center- Time to Change Our Paradigm for Liver Transplant

    A. Humar, D. Jorgensen, S. Ganesh, A. Tevar, M. Molinari, C. Hughes

    Thomas E Starzl Transplant Inst, Pittsburgh, PA

    *Purpose: LDLT remains underutilized in the US. We compared outcomes between LDLT and DDLT at our center to highlight the advantages of LDLT.*Methods: Retrospective review…
  • 2019 American Transplant Congress

    Improving Access to Lung Transplant through Donor Strategy: A Decision Analysis

    W. Tsuang, B. Udeh

    Cleveland Clinic, Cleveland, OH

    *Purpose: The use of Donation after Cardiac Death (DCD) donors in addition to Donation after Brain Death (DBD) donors may increase patient access to lung…
  • 2019 American Transplant Congress

    Platelets Augment Granzyme K Production By Macrophages In Antibody-mediated Rejection

    J. Dhar, K. Keslar, R. Fan, N. Dvorina, W. Baldwin

    Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH

    *Purpose: When antibodies bind to MHC antigens on endothelial cells a cascade of responses is initiated including exocytosis of adhesion molecules followed by attachment and…
  • 2019 American Transplant Congress

    Variation in Racial Disparities in Liver Transplant Outcomes by Hospital Quality

    K. Ross, R. Patzer, R. Lynch

    Emory University, Emory Transplant Center, Atlanta, GA

    *Purpose: Black patients experience inferior outcomes after liver transplant (LTx). Studies of other outcomes have shown that disparities are partially attributable to variation in quality…
  • 2019 American Transplant Congress

    Increasing Time-in-Therapeutic Range of Tacrolimus is Associated with Superior Outcomes in Living Kidney Transplants

    T. Lin, T. Song, S. Yin, Y. Jiang, Z. Huang, X. Wang, J. Liu, Z. Wang

    Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China

    *Purpose: Tacrolimus-based regimens remain the backbone of maintenance immunosuppressive therapy in kidney transplant, and therapeutic drug monitoring of tacrolimus is necessary due to a narrow…
  • 2019 American Transplant Congress

    Positron Emission Tomography (PET-CT) Global Coronary Flow Reserve (CFR) Stratifies Cardiovascular Risk among Renal Transplant (RTx) Candidates

    M. Minder, S. Mason, J. Ethington, R. McCubrey, D. Min, N. Sekaran, J. Orford, D. Morris, S. Anand, T. Srinivas

    Intermountain Healthcare, Murray, UT

    *Purpose: Chronic kidney disease (CKD) and diabetes (DM) are both associated with increased risk of coronary artery disease and Major Adverse Cardiovascular Events (MACE). The…
  • 2019 American Transplant Congress

    Chronic Kidney Disease among Liver Transplant Candidates: A Rising Burden and Its Impact on Post-Liver Transplant Outcomes

    G. Cullaro1, E. C. Verna2, B. P. Lee1, J. C. Lai1

    1UCSF, San Francisco, CA, 2Columbia University, New York, NY

    *Purpose: Chronic kidney disease (CKD) is the end manifestation of persistent renal damage, a pathology distinct from the reversible acute kidney injury (AKI). This distinction…
  • 2019 American Transplant Congress

    TIPS Effectively Treats Refractory Hepatic Hydrothorax: A Multi-Center U.S. Retrospective Study of 1,260 Patients

    M. German1, A. Lee1, A. Hristov1, A. Said1, J. Boike2, J. Ge3, N. Jest4, G. Morelli4, K. Kolli3, J. Lai3, A. Desai5, S. Junna6, B. Pokhrel6, T. Couri7, S. Paul7, C. Frenette8, N. Christian-Miller8, E. Verna9, U. Rahim10, A. Goel10, A. Das2, S. Pine2, D. Gregory2, L. VanWagner2, E. Spengler1

    1University of Wisconsin, Madison, WI, 2Northwestern University, Chicago, IL, 3University of California, San Francisco, San Francisco, CA, 4University of Florida, Gainesville, FL, 5University of Indiana, Indianapolis, IN, 6University of Arizona, Tucson, AZ, 7University of Chicago, Chicago, IL, 8Scripps Clinic, San Diego, CA, 9Columbia University, New York, NY, 10Stanford University, Palo Alto, CA

    *Purpose: Hepatic hydrothorax (HHT) occurs in 5-10% of patients with cirrhosis. Current literature on the use of transjugular intrahepatic portosystemic shunt (TIPS) in the treatment…
  • 2019 American Transplant Congress

    Optimal Timing of Hepatitis C Treatment among HIV/HCV Co-Infected End-Stage Renal Disease Patients: Pre vs. Post-Transplant

    B. Shelton1, G. Berdahl1, D. Sawinski2, B. Linas3, P. Reese2, M. Mustian1, R. Reed1, P. MacLennan1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 3Boston University School of Medicine, Boston, MA

    *Purpose: End-stage renal disease (ESRD) patients co-infected with HCV and HIV have access to effective treatment options for HCV infection. However, they also have access…
  • 2019 American Transplant Congress

    miR-20a Inhibits Autophagy by Targeting AKT and BIM in Renal Reperfusion Injury

    T. Lin, T. Song, Y. Jiang, J. Liu, Z. Wang, L. Li, Z. Huang, Y. Fan, X. Wang

    Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China

    *Purpose: Previously, we found up-regulation of miR-20a after kidney ischemia reperfusion (I/R) injury and may serves as a protector; however, its specific mechanism remains unclear.Autophagy…
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