Am J Transplant, Volume 19, Suppl 3 Archives - Page 169 of 214 - ATC Abstracts

2019 American Transplant Congress
“Getting Life Back” – Kidney Transplantation in the Elderly Patient
V. Tsarpali¹, K. Lønning², K. Midtvedt², T. Bernklev³, N. von der Lippe⁴, M. H. Andersen², K. Heldal¹
¹Clinic of Internal Medicine, Telemark Hospital Trust, Skien, Norway, ²Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway, ³Vestfold Hospital Trust, Tønsberg, Norway, ⁴Oslo University Hospital, Oslo, Norway
*Purpose: The number of elderly patients developing end stage renal disease (ESRD) who are eligible for kidney transplantation (KTx) is increasing, but their transplant rate…
2019 American Transplant Congress
CyTOF and RNAseq Analyses Unravel Early Phenotypic and Transcriptional Changes in Antibody-Secreting and Memory B Cells >1 Year Prior to Antibody-Mediated Rejection
C. Fischman¹, M. Fribourg¹, J. Ansari², L. Gallon², F. Ginevri³, P. Comoli⁴, M. Cioni³, A. Nocera³, M. Bruschi³, C. Cantarelli¹, L. Perin⁵, P. Cravedi¹
¹Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ²Department of Medicine, Northwestern University, Chicago, IL, ³Department of Medicine, IRCCS Istituto G. Gaslini, Genoa, Italy, ⁴Department of Medicine, IRCCS San Matteo Hospital, Pavia, Italy, ⁵Department of Urology, Children's Hospital Los Angeles, Los Angeles, CA
*Purpose: While the negative impact of anti-HLA donor specific antibodies (DSA) on graft outcomes has been extensively investigated, little is known about early changes in…
2019 American Transplant Congress
Histone Deacetylase-2 Knockout in Renal Tubular Cells is Protective in Renal Ischemia-Reperfusion Injury
P. T. Hernandez¹, S. J. Concors¹, L. Krumeich¹, D. D. Aufhauser¹, Z. Wang¹, D. D. Murken¹, G. Ge¹, W. Hancock², M. Levine³
¹General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ²Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, ³Transplant Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA
*Purpose: Ischemia-reperfusion injury (IRI) is a major source of morbidity in renal transplantation and is without targeted therapy. In renal transplantation, IRI contributes to poorer…
2019 American Transplant Congress
National Trends in Bariatric Surgical Practice for Patients with End-Stage Renal Disease
K. H. Sheetz¹, K. J. Woodside¹, V. B. Shahinian², J. B. Dimick¹, S. A. Waits¹
¹Department of Surgery, University of Michigan Hospitals and Health System, Ann Arbor, MI, ²Department of Internal Medicine, University of Michigan Hospitals and Health System, Ann Arbor, MI
*Purpose: Despite growing enthusiasm for the use of bariatric surgery in obese patients with end-stage renal disease (ESRD), national practice patterns in this patient population…
2019 American Transplant Congress
Patterns of Rejection in Murine, Porcine, and Human Vascularized Composite Allografts Based on Clinical, Histologic, and Immunohistochemical Analysis
M. J. Grzelak, J. W. Etra, F. A. Chang, G. J. Furtmüller, A. R. Ahmadi, F. Nägele, Y. Guo, K. Kambarashvili, A. Jain, S. A. Beck, C. F. Brayton, I. B. Sander, W. A. Lee, G. Brandacher
Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: The side effects of chronic immunossupression limit the more extensive use of Vascularized Composite Allotransplantation (VCA), and because reliable pre-clinical animal models will be…
2019 American Transplant Congress
Comparison of Pregnancy Outcomes by Conception Age in Female Kidney Transplant Recipients
S. Rao¹, L. A. Coscia², D. Kliniewski², S. Constantinescu³, M. J. Moritz⁴
¹Medicine, University of Virginia Health System, Charlottesville, VA, ²Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA, ³Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, ⁴Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: The purpose of this study is to compare pregnancy outcomes in 1066 female kidney transplant recipients by different conception ages.*Methods: Data were collected by…
2019 American Transplant Congress
Nothing Lasts Forever, So Of The Donor Risk Index For Liver Transplant
K. Okubo, K. Sasaki, A. Moro, J. McBey, M. Fujiki, T. Diago Uso, B. Eghtesad, D. Kwon, C. Miller, C. Quintini, K. Hashimoto, F. Aucejo
Cleveland Clinic, Cleveland, OH
*Purpose: The donor risk index (DRI) is one of the most established risk indices in liver transplant (LT). DRI, which was reported in 2006, was…
2019 American Transplant Congress
Geographic Trends in Drug Intoxicated Deceased Donor Recovery and Utilization
R. Urban, D. Klassen, J. Rosendale
United Network for Organ Sharing, Richmond, VA
*Purpose: The impact of the current opioid epidemic has been felt throughout the nation, and has seen significant geographic variation in the impact on decease…
2019 American Transplant Congress
High Fibre Diet Prevents Transplant-Associated Dysbiosis and Prevents Kidney Allograft Rejection
J. J. Singer¹, H. Wu¹, T. Kwan¹, Y. Loh¹, C. Wang¹, J. Tan², L. Macia², S. Alexander³, S. Chadban¹
¹Kidney Node Laboratory, Charles Perkins Centre, The University of Sydney, Sydney, Australia, ²Nutritional Immunometabolism Lab, Charles Perkins Centre, The University of Sydney, Sydney, Australia, ³The Children's Hospital Westmead, Sydney, Australia
*Purpose: To investigate the impact of high fibre (HF) diet or dietary supplementation with the short chain fatty acid (SCFA) sodium acetate (SA) on kidney…
2019 American Transplant Congress
Bronchoalveolar Lavage Biomarkers Predict Lung Transplant Survival
A. Zarinsefat¹, J. Y. Yang², R. Sarwal¹, J. Liberto¹, D. Watson³, S. Verleden⁴, M. Sarwal¹
¹UC San Francisco, San Francisco, CA, ²Johns Hopkin, Baltimore, MD, ³Kit Bio, Los Altos, CA, ⁴KU Leuven, Leuven, Belgium
*Purpose: In lung transplants (LTx), chronic rejection remains a major cause of morbidity and mortality following transplantation, mainly from chronic lung allograft dysfunction (CLAD). Two…