Am J Transplant, Volume 19, Suppl 3 Archives - Page 159 of 214 - ATC Abstracts

2019 American Transplant Congress
Long-Term Outcomes of Early Conversion to Sirolimus-Based Immunosuppression in Children with Living Donor Kidney Transplants
B. Stotter¹, S. Lui¹, E. Weller², L. Ganapathi¹, M. Ferguson¹, A. Traum¹, M. Somers¹, N. Rodig¹
¹Pediatrics, Boston Children's Hospital, Boston, MA, ²Biostatistics and Research Design Center, Boston Children's Hospital, Boston, MA
*Purpose: Following kidney transplantation (KTx), calcineurin inhibitor (CNI)-based maintenance immunosuppression (IS) can be associated with nephrotoxicity and other complications including viral infections and malignancy. Mammalian…
2019 American Transplant Congress
Outcomes of En Bloc Simultaneous Liver-Kidney Transplantation Compared to the Traditional Technique
A. R. Cortez, T. C. Lee, A. Kassam, M. C. Morris, L. K. Winer, L. Sage Silski, M. C. Cuffy, T. S. Diwan, R. C. Quillin, S. A. Shah
University of Cincinnati, Cincinnati, OH
*Purpose: Simultaneous liver-kidney transplantation (SLKT) is indicated for patients with end-stage liver disease (ESLD) and concurrent renal insufficiency. En bloc SLKT has been reported as…
2019 American Transplant Congress
Liver Transplant Centers Select Different Characteristics for Recipients and Deceased Donors: Implications for Patients When Choosing a Center
C. R. Schaffhausen¹, M. J. Bruin², S. Chu², D. Schladt¹, S. Chinnakotla³, J. R. Lake⁴, W. Kim⁵, S. W. Biggins⁶, J. J. Snyder⁷, B. L. Kasiske⁷, A. K. Israni¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, Minneapolis, MN, ³Department of Surgery, University of Minnesota, Minneapolis, MN, ⁴Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, MN, ⁵Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, ⁶Division of Gastroenterology, University of Washington, Seattle, WA, ⁷Scientific Registry of Transplant Recipients, Minneapolis, MN
*Purpose: When patients can choose the liver transplant center at which to establish care, a prior knowledge of center acceptance practices (of candidates and donors)…
2019 American Transplant Congress
De-Novo Letermovir Resistant Mutations in Cytomegalovirus-Infected Tissues of Solid Organs Transplant Recipients
S. HAN, H. Cho, S. Min, Y. Hong
Internal Medicine, Yonsei University Health System, Yonsei University College of Medicine, Seoul, Korea, Republic of
*Purpose: Letermovir, cytomegalovirus (CMV) DNA-terminase complex (UL51, UL56, and UL89) inhibitor, revealed the efficient prophylactic effect against CMV infection including disease and DNAemia with low-grade…
2019 American Transplant Congress
Candida auris after Liver Transplant
N. M. Theodoropoulos, R. Ellison, J. S. Daly, A. Bozorgzadeh, D. A. Mack, L. Gibson, S. M. Levitz
University of Massachusetts Medical School, Worcester, MA
*Purpose: C. auris is a difficult to eradicate yeast that has caused outbreaks in hospitals in recent years. We report a cluster of liver transplant…
2019 American Transplant Congress
Need For Protocol Driven Mmr/vzv Serologic Screening
A. Agarwal¹, L. Brumble¹, H. Wadei², C. Libertin¹
¹Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL, ²Department of Transplant, Mayo Clinic, Jacksonville, FL
*Purpose: The current American Society of Transplantation-ID guidelines recommend the MMR and VZV serologic screening pre transplantation for of all persons born after 1956. MMR…
2019 American Transplant Congress
Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant
N. A. Wickramaratne¹, R. Li², R. C. Fyffe-Freil², T. Tian², M. J. Mangino²
¹VCUHealth, Richmond, VA, ²Department of Surgery, VCUHealth, Richmond, VA
*Purpose: Epithelial-to-mesenchymal transition (EMT) is a genetic reprogramming that causes epithelial cells to assume a migratory, mesenchymal phenotype, and it is induced by hypoxia. Ischemic…
2019 American Transplant Congress
CD47 Blockade Promotes Hepatic Macrophage Polarization toward M1 during Normothermic Machine Perfusion of Discarded Human Livers
M. Xu¹, F. Zhou¹, S. Garcia-Aroz¹, B. Banan¹, W. Yang², G. Upadhya¹, K. Byrnes³, B. Wong¹, P. Manning⁴, Y. Lin¹, W. Chapman¹
¹Department of Surgery, Washington University School of Medicine, St. Louis, MO, ²Department of Genetics, Washington University School of Medicine, St. Louis, MO, ³Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, ⁴Arch Oncology, St. Louis, MO, USA, St. Louis, MO
*Purpose: M1 macrophages have been shown to be able to phagocytize dead cells after ischemia-reperfusion injury (IRI). This study investigated the therapeutic effect of CD47…
2019 American Transplant Congress
miRNA Signatures as Prediction Tool for DSA Development and Rejection
M. Hamdorf¹, L. M. Rebellato², K. P. Briley², M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²East Carolina University, Greenville, NC
*Purpose: Early and convenient diagnosis is urgently needed for acute and chronic transplant rejection due to its high risk of the loss of the transplant.…
2019 American Transplant Congress
Functional Dependence, Access to Kidney Transplantation and Waitlist Mortality
A. Muzaale¹, N. Chu¹, H. Ying¹, S. Norman², S. Sison¹, D. Segev¹, M. McAdams-Demarco¹
¹JHU, Baltimore, MD, ²UM, Ann Habor, MI
*Purpose: Among patients with ESRD, functional dependence is common and an important determinant of both HRQOL and adverse outcomes. Kidney transplant (KT) may help patients…