Am J Transplant, Volume 19, Suppl 3 Archives - Page 151 of 214 - ATC Abstracts

2019 American Transplant Congress
The Model For Predicting eGFR At A Year After Donation In Living Related Kidney Transplant Donors
K. Shinoda, K. Sakurabayashi, T. Mizutani, Y. Takahashi, Y. Hyodo, Y. Itabashi, M. Muramatsu, T. Kawamura, S. Shishido, K. Sakai
Nephrology, Toho University Faculty of Medicine, Tokyo, Japan
*Purpose: Predicting post-donation kidney function precisely is considerably beneficial for both candidates of living-related kidney donors and their physicians when judging the feasibility of kidney…
2019 American Transplant Congress
Patterns and Predictors of Alcohol Use after Early Liver Transplant for Alcoholic Hepatitis
B. P. Lee¹, M. Rinella², G. Im³, J. Rice⁴, O. Fix⁵, G. Therapondos⁶, H. Han⁷, D. Victor⁸, E. Weinberg⁹, C. Hsu¹⁰, M. Voigt¹¹, H. Maddur², S. Eswaran¹², D. Foley⁴, R. Ghobrial⁸, L. Dinges⁵, J. Dodge¹, N. Mehta¹, M. Lucey⁴, N. Terrault¹
¹UCSF, SF, CA, ²NW, Chicago, IL, ³MtSinai, NYC, NY, ⁴Wisconsin, Madison, WI, ⁵Swedish, Seattle, WA, ⁶Ochsner, Jefferson, LA, ⁷USC, LA, CA, ⁸Houston, Houston, TX, ⁹Penn, Philadelphia, PA, ¹⁰Georgetown, DC, WA, ¹¹Iowa, Iowa City, IA, ¹²Rush, Chicago, IL
*Purpose: ACCELERATE-AH is a multicenter consortium studying early liver transplant (LT) for alcoholic hepatitis (AH). To inform surveillance and intervention strategies for post-LT alcohol use,…
2019 American Transplant Congress
Monitoring Circulating T Follicular Helper Cells Polarization, Activation and Function Distinguishes Asymptomatic Donor-Specific Anti-HLA Antibody Positive Kidney Transplant Recipients from Those Undergoing Antibody-Mediated Rejection
C. Macedo¹, K. Louis¹, P. Fadakar², M. Yamada², B. Elinoff¹, K. Hadi¹, P. Randhawa¹, D. Metes¹
¹Starzl Transplantation Institute, Pittsburgh, PA, ²Children's Hospital of Pittsburgh, Pittsburgh, PA
*Purpose: Donor-specific anti-HLA antibodies (DSA) represent an important biomarker for acute rejection and are a major cause of long-term graft failure after kidney transplantation (KTx).…
2019 American Transplant Congress
Differentiation and Characterization of Human Endodermal Precursors for Liver Cell Therapies
W. S. Fagg¹, N. Liu¹, M. Shoja¹, I. Patrikeev², M. Motamedi², J. Fair¹
¹Surgery, University of Texas Medical Branch, Galveston, TX, ²Opthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, TX
*Purpose: Mouse pluripotent stem cell (PSC)-derived endoderm precursors (EPs) have small size, endoderm lineage gene expression signatures, and high proliferation rates, that allow engraftment in…
2019 American Transplant Congress
Improving the Organ Donation Process: Updated
J. Yeh, M. P. Jarrett, L. Teperman
Northwell Health, New Hyde Park, NY
*Purpose: Due to the complexity of care that each ICU patient requires, the bedside nurse may miss the clinical trigger that would indicate an appropriate…
2019 American Transplant Congress
Central Role of Graft Resident Memory T Cells in Pathogenesis of GVHD after Bowel Transplantation
J. Weiner, N. Svetlicky, J. Schmidt, S. Moturi, O. Aguirre, J. Kang, M. Sadat, K. Khan, J. Hawksworth, C. Matsumoto, T. Fishbein, A. Kroemer
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Graft-versus-host disease (GVHD) is a relatively common and highly morbid complication after intestinal transplantation. Its pathophysiology remains poorly understood. Resident memory T cells (TRM)…
2019 American Transplant Congress
Dual Treatment of CD40 Silencing or Mesenchymal Stem Cells Infusion with Sub-Therapeutic Doses of Cyclosporine Effectively Prevents Acute Rejection in an Allogenic Model of Renal Transplantation
J. Guiteras¹, L. De Ramon¹, N. Bolaños¹, M. Franquesa², M. Gomà³, J. Cruzado⁴, N. Lloberas¹, J. Grinyó⁴, J. Torras⁴
¹IDIBELL, Hospitalet de Llobregat, Spain, ²IGTP, Badalona, Spain, ³Bellvitge Hospital, Hospitalet de Llobregat, Spain, ⁴Bellvitge Hospital / IDIBELL, Hospitalet de Llobregat, Spain
*Purpose: This study was designed to investigate the combination of CD40 silencing or MSC infusion with suboptimal doses of Cyclosporine in this renal allograft model.*Methods:…
2019 American Transplant Congress
In Vitro Model to Study the Effect of Irradiation Preconditioning on Alloimmune Responses: Development of Potential Predictive Markers
K. Shimozawa, K. Janec, L. Contreras-Ruiz, E. C. Guinan
Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
*Purpose: Pre-conditioning using total body irradiation prior to HSCT is a well-established regimen for patients with hematological malignancy. However, irradiation (IR) elicits not only immunosuppressive…
2019 American Transplant Congress
Development of Non-Human Leukocyte Antigen Antibodies in Cardiac Antibody-Mediated Rejection
S. B. See¹, B. S. Mantell², K. J. Clerkin³, B. Ray⁴, E. R. Vasilescu⁵, C. Marboe⁵, Y. Naka⁶, S. Restaino¹, P. C. Colombo³, L. J. Addonizio², M. A. Farr³, E. Zorn¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Division of Cardiology, Columbia University, New York, NY, ⁴Immucor, Georgia, GA, ⁵Department of Pathology and Cell Biology, Columbia University, New York, NY, ⁶Department of Surgery, Columbia University, New York, NY
*Purpose: Antibody-mediated rejection (AMR), mainly driven by the development of donor-specific antibodies (DSA) directed against mismatched donor class I and class II HLA, is a…
2019 American Transplant Congress
Efficacy of Photobiomodulatory Therapy Combined with Short-Term Immunosuppressants Prolonged Allograft Survival in a Rodent Hind-Limb Model
Y. KUO¹, Y. Li¹, C. Chen¹, R. Chen1¹, G. Brandacher²
¹Division of Plastic Surgery, Department of Surgery,, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ²Department of Plastic Surgery, VCA center, Johns Hopkins University, Baltimore, MD
*Purpose: Photobiomodulation has been applied for accelerating the skeletal muscle repair process. Our formal study demonstrated vitamin D could be involved in allograft survival and…