ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Machine Perfusion Allows Use of High KDPI and Prolonged Cold Ischemia Time in Deceased Donors: A Single Center Effort to Decrease Discard Rates

    M. Ortigosa-Goggins, J. Gaynor, A. Mattiazzi, J. Figueiro, G. Burke, G. Ciancio, G. Guerra

    Miami Transplant Institute, University of Miami, Miami, FL

    *Purpose: Discard rates of deceased donor kidney transplants(DDKT)rises as the kidney donor profile index(KDPI)increases,and approaches 60%for KDPI of >85%.Pulsatile machine perfusion(MP)allows use of kidneys with…
  • 2019 American Transplant Congress

    The Outcomes after an Infection in Older Liver Transplant Recipients is Comparable to Younger Adults

    J. Garcia-Diaz1, M. Kerkelis2, T. Shah3, M. Tucker4, M. Gastanaduy5, J. Woo1, M. Ponder1, M. Malinis6, M. Malinis6

    1Infectious Diseases, Ochsner Medical Center, New Orleans, LA, 2University of Queensland/Ochsner Clinical School, New Orleans, LA, 3Internal Medicine, St. Joseph Hospital, Denver, CO, 4Internal Medicine, Yale School of Medicine, New Haven, CT, 5Center for Outcomes and Health Services Research, Ochsner Medical Center, New Orleans, LA, 6Infectious Diseases, Yale School of Medicine, New Haven, CT

    *Purpose: Solid organ transplantation is being increasingly offered to older patients with concurrent chronic medical conditions such as cardiovascular, cerebrovascular, and renal disease. Risk of…
  • 2019 American Transplant Congress

    Super-resolution Evaluation Of The Glomerular Basement Membrane Changes In The Course Of Transplant Glomerulopathy

    D. Hammad, J. H. Miner, T. Alhamad, H. Suleiman

    Washinton University in St. Louis, St. Louis, MO

    *Purpose: Transplant Glomerulopathy (TG) is a histologic entity that affects around 20% of kidney allografts by 5 years post transplantation and results in a significant…
  • 2019 American Transplant Congress

    The Role of CD47/SIRPα and CD47/TSP-1 Pathways in Pig-to-Baboon Kidney Transplantation Using hCD47 Transgenic Kidneys

    K. Takeuchi1, Y. Ariyoshi1, T. Pomposelli1, L. Boyd1, D. Ekanayake-Alper1, S. Arn1, R. Hawley1, D. Ayares2, M. Lorber3, M. Sykes1, D. Sachs1, R. Johnson4, K. Yamada1

    1CCTI/Surgery, Columbia University Medical Center, New York, NY, 2Revivicor Inc., Blacksburg, VA, 3Lung BioTechnology PBC, Silver Spring, MD, 4Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO

    *Purpose: We have recently reported that both CD80 upregulation and the degradation of SMPDL-3b on glomerular podocytes are involved in the development of post kidney…
  • 2019 American Transplant Congress

    Increased Access to Transplantation for Medicaid Patients Following Medicaid Expansion

    A. Massie, M. Henderson, T. Hwee, D. Segev

    Johns Hopkins, Baltimore, MD

    *Purpose: Under the Patient Protection and Affordable Care Act (ACA), states in the United States had the option of expanding Medicaid eligibility. 24 states adopted…
  • 2019 American Transplant Congress

    Facial Composite Tissue Allotransplantation: First Canadian Experience

    S. Collette1, A. Govshievich2, S. F. Dufresne1, D. Désy1, H. St-Jacques1, D. Borsuk1

    1Hopital Maisonneuve-Rosemont, Montreal, QC, Canada, 2University of Montreal, Montreal, QC, Canada

    *Purpose: Facial vascularized composite allotransplantation (VCA) has emerged as a groundbreaking reconstructive solution for patients with severely disfiguring facial injuries. It allows simultaneous “like with…
  • 2019 American Transplant Congress

    Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection

    D. Kumar1, M. Raynaud2, P. Halloran3, A. Loupy2, J. Chang3, J. Reeve3, I. Yakubu1, S. Bobba1, L. Kamal1, M. Levy1, C. Bhati1, P. Kimball1, A. King1, G. Gupta1

    1Virginia Commonwealth University, Richmond, VA, 2Paris Transplant Group, Paris, France, 3Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada

    *Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause of long-term kidney transplant (KT) loss. Current therapies have unclear efficacy and significant side…
  • 2019 American Transplant Congress

    Preemptive Therapy is Cost Effective When Compared to Prophylaxis in Cytomegalovirus Donor Positive – Recipient Negative Liver Transplant Recipients

    M. M. Wagener1, D. J. Winston2, R. R. Razonable3, G. M. Lyon III4, F. P. Silveira5, A. P. Limaye6, N. Singh1

    1ID, U Pittsburgh and VAPHS, Pittsburgh, PA, 2ID, UCLA, Los Angeles, CA, 3ID, Mayo Clinic, Rochester, MN, 4ID, Emory, Atlanta, GA, 5ID, U Pittsburgh, Pittsburgh, PA, 6ID, U Washington, Seattle, WA

    *Purpose: To compare the cost effectiveness of preemptive therapy (PET) vs prophylaxis for the prevention of cytomegalovirus (CMV) in high-risk donor seropositive/recipient seronegative (D+R-) liver…
  • 2019 American Transplant Congress

    Association between Medicaid Expansion under the Affordable Care Act and Preemptive Kidney Transplantation of Low-Income Medicaid Beneficiaries

    M. N. Harhay1, R. McKenna2

    1Medicine, Drexel University College of Medicine, Philadelphia, PA, 2Health Management and Policy, Drexel University Dornsife School of Public Health, Philadelphia, PA

    *Purpose: The lack of affordable health insurance options is a known barrier to preemptive kidney transplantation (KT) among low-income individuals with non-dialysis dependent chronic kidney…
  • 2019 American Transplant Congress

    Resolution of Hyperglycemia Following Islet Allograft Transplantation in Non-Immunosuppressed Mice

    J. Ge1, K. Lee1, C. Yang1, R. White2, I. Rosales2, P. Russell1, C. Rickert1, J. Markmann1, J. Madsen1, R. Colvin2, A. Alessandrini1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Pathology, Massachusetts General Hospital, Boston, MA

    *Purpose: Kidney allografts are naturally tolerogenic in mice. Certain mouse strain combinations develop tolerance of kidney allografts across full MHC incompatibilities without immunosuppression (e.g. DBA/2…
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