Am J Transplant, Volume 19, Suppl 3 Archives - Page 136 of 214 - ATC Abstracts

2019 American Transplant Congress
Non-adherence With Diet And Dialysis Prescription: Predictors Of Non-adherence Post-transplant?
A. Padiyar¹, A. Agrawal¹, D. Hricik¹, P. Bate², J. Rockwell², A. Eliason², N. Sarabu¹, A. Jittirat¹, K. Yadav², E. Sanchez², M. Debroy², V. Humphreville², J. Rabets², A. Palanisamy², K. Chavin²
¹Medicine, Nephrology, University Hospitals Cleveland Medical Center, Cleveland, OH, ²Transplant Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Perceived non-adherence with diet and dialysis prescription prior to transplant may be seen as a risk for non-adherence with immunosuppression post-transplant. The importance of…
2019 American Transplant Congress
Mitochondrial Dysfunction and Metabolic Reprogramming: Critical Features of Cyclosporine A Nephrotoxicity
A. A. Zmijewska, G. Benavides, V. Darley-Usmar, J. W. Zmijewski, R. B. Mannon
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Calcineurin inhibitors (CNIs) are potent immunosuppressants but over time contribute to allograft fibrosis. Clinical efforts to minimize or avoid CNI have not been uniformly…
2019 American Transplant Congress
An Immediate and Persistent Post-Reperfusion Metabolic Collapse Precedes Delayed Graft Function (DGF)
J. Lindeman
Surgery, Leiden University Medical Center, Leiden, Netherlands
*Purpose: Delayed graft function (DGF) is the manifestation of ischemia reperfusion injury (IRI) in the context of kidney transplantation. Despite clear preclinical successes, a proven…
2019 American Transplant Congress
Post-operative Opioid Requirements In Living Kidney And Liver Donors
H. J. Braun, D. Adelmann, T. Grace, M. E. Pulcrano, C. U. Niemann, N. L. Ascher
University of California, San Francisco, San Francisco, CA
*Purpose: The United States faces an opioid epidemic. Approximately 6% of opioid-naïve surgical patients will develop opioid dependence post-operatively, and the CDC found that patients…
2019 American Transplant Congress
A Prospective Randomized Multicenter Trial (B E S T Trial) of Belatacept-Based C N I- and Corticosteroid-Free Immunosuppression: Final Two Year Results
D. B. Kaufman¹, A. R. Shields², J. P. Leone³, A. Wiseman⁴, A. J. Matas⁵, P. West-Thielke⁶, J. Lipscomb², E. King², R. R. Alloway⁷, E. S. Woodle for the BEST Study Group²
¹University of Wisconsin, Madison, WI, ²University of Cincinnati, Cincinnati, OH, ³Tampa General, Tampa, FL, ⁴University of Colorado School of Medicine, Denver, CO, ⁵University of Minnesota, Minneapolis, MN, ⁶University of Illinois, Chicago, Chicago, IL, ⁷University of Cincinnati, Cincinnati, WI
*Purpose: The BEST Trial (Belatacept-based Early Steroid Withdrawal Trial) is a prospective, randomized, multi-center trial designed to compare two belatacept (BELA)-based calcineurin inhibitor-free (CNI), early…
2019 American Transplant Congress
Extremes of Body Mass Index is Associated with Inferior Renal Allograft Outcomes in Type 2 Diabetic Deceased Donor Renal Transplant Recipients
A. Brar, A. Gruessner, F. Tedla, R. Gruessner, J. Renz, N. Sumrani, D. John, M. O. Salifu
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We evaluated the trends and renal allograft outcomes in type 2 diabetic renal transplant recipients stratified by body mass index (BMI).*Methods: All adult type…
2019 American Transplant Congress
HOPE in Action: A Multicenter Prospective Study of HIV to HIV Liver Transplantation
C. Durand¹, S. Florman², M. Bowring³, D. Brown¹, B. Haydel², J. Hamilton¹, P. Stock⁴, J. Price⁵, T. Pruett⁶, V. Kirchner⁷, D. Wojciechowksi⁸, N. Turgeon⁹, C. Wolfe¹⁰, V. Stosor¹¹, J. Charette¹¹, A. Cameron³, S. Ottmann³, S. Huprikar¹², D. Segev³
¹Medicine, Johns Hopkins University, Baltimore, MD, ²Surgery, Mount Sinai, New York, NY, ³Surgery, Johns Hopkins University, Baltimore, MD, ⁴Surgery, University of California San Francisco, San Francisco, CA, ⁵Medicine, University of California San Francisco, San Francisco, CA, ⁶Surgery, University of Minnesota, Minneapolis, MN, ⁷Medicine, University of Minnesota, Minneapolis, MN, ⁸Medicine, Mass General Hospital, Boston, MA, ⁹Surgery, Emory University, Atlanta, GA, ¹⁰Medicine, Duke University, Durham, NC, ¹¹Medicine, Northwestern University, Chicago, IL, ¹²Medicine, Mount Sinai, New York, NY
*Purpose: HIV+ liver transplant (LT) candidates face higher mortality and lower access to transplant compared to HIV- counterparts. With the US HOPE Act, HIV+ donor…
2019 American Transplant Congress
Biomarker Candidate Discovery for Kidney Allograft Monitoring via Urinary Exosome Proteome Analysis
J. Kim¹, Y. Wee¹, M. Choi¹, H. Jung¹, J. Choi¹, H. Kwon¹, J. Jung¹, Y. Ko¹, D. Kim¹, K. Kim², Y. Cho³, H. Go³, Y. Kim¹, D. Han¹, S. Shin¹
¹Department of Surgery, Asan Medical Center, Seoul, Korea, Republic of, ²Department of Convergence Medicine, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea, Republic of, ³Department of Pathology, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: There is a need for the development of noninvasive molecular biomarkers with high reliability and predictive power for early diagnosis and monitoring of any…
2019 American Transplant Congress
Murine Cmv Infection Impairs Transplantation Tolerance: A Critical Role Of Intragraft Anergic Cd4 T Cells
A. Dangi¹, E. B. Thorp², X. Luo¹
¹Medicine, Duke University, Durham, NC, ²Pathology, Northwestern University, Chicago, IL
*Purpose: It is well known that certain infections can impair the stability of transplantation tolerance in recipients who had prolonged functional grafts, resulting in graft-loss.…
2019 American Transplant Congress
Decline in Club Cell Secretory Protein Results in Immune Responses to Lung Self-Antigens (Kα1 Tubulin and Collagen V) and Development of Chronic Rejection Following Human Lung Transplantation
Y. Itabashi¹, R. Ravichandran¹, M. Sharma¹, R. Hachem², R. Bremner¹, M. Smith¹, T. Mohanakumar¹
¹Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ, ²Washington University School of Medicine, St. Louis, MO
*Purpose: Club cell secretory protein (CCSP) levels have been employed as a biomarker for respiratory stress in athletes, asthma patients, and in experimental acute and…