Am J Transplant, Volume 19, Suppl 3 Archives - Page 135 of 214 - ATC Abstracts

2019 American Transplant Congress
Donor Derived Strongyloidiasis, a Preventable Event
R. M. La Hoz¹, G. Vece², L. Danziger-Isakov¹, D. Florescu¹, M. Malinis¹, K. Lilly¹, L. Strasfeld¹, R. P. Wood¹, S. Tlusty², C. R. Wolfe¹, M. G. Michaels¹
¹DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: In the US, deceased donor screening for Strongyloides started in 2010. By 2013 10% of the OPOs had implemented screening practices. Recipients of sero-positive…
2019 American Transplant Congress
Predictors of Clostridium difficile Infection and Recurrence among 2,622 Solid Organ Transplant Recipients
A. Schluger, R. Rosenblatt, R. Knotts, E. Verna, M. Pereira
Columbia University, New York, NY
*Purpose: Clostridium difficile infection (CDI) is common after solid organ transplant (SOT) and is associated with high morbidity and mortality. We assessed incidence, risk factors…
2019 American Transplant Congress
The Economic Impact of Surgical Site Infections in Liver Transplantation
Y. Natori¹, D. Kumar², A. Humar², S. Husain², C. Rotstein³
¹Miami Transplant Institute, University of Miami, Miami, FL, ²Transplant Infectious Diseases, University of Toronto, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada
*Purpose: Complications arising after liver transplantation result in additional healthcare costs. Previous studies have not evaluated the impact of surgical site infections on healthcare costs…
2019 American Transplant Congress
Inhibition of TLR4 Mediated Programmed Necrosis Does Not Improve Graft Function and Histology in a Murine Kidney Transplant Model
S. Jain¹, R. Plenter², T. Nydam², A. Jani¹
¹Renal Division, University of Colorado, Aurora, CO, ²Transplant Microsurgery Program, University of Colorado, Aurora, CO
*Purpose: Human Delayed Graft Function (DGF) is associated with upregulation of basolateral tubular TLR4 but whether TLR4 causes DGF is unknown. TLR4 has been shown…
2019 American Transplant Congress
Ischemia-Free Liver Transplantation Protects Bile Duct from Ischemia/Reperfusion Injury
J. Yang, S. Huang, Z. Zhang, Q. Zhao, W. Ju, Z. Zhu, Y. Tang, L. Wang, Y. Zhang, C. Sun, L. Wu, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Ischemia-free liver transplantation (IFLT), based on normothermic machine perfusion and innovations in surgical technique, can provide continue blood supply from procurement to implantation that…
2019 American Transplant Congress
The Negative Costimulatory Pd-1/pd-l1 Pathway Is Upregulated In Early Cell-mediated Rejection
T. Kurashige, R. Khedraki, K. Keslar, N. Dvorina, W. Baldwin
Cleveland Clinic Main Campus, Lerner Research Institute, Cleveland, OH
*Purpose: Extensive transcript analysis has been performed on grafts at the time of rejection, but gene expression preceding overt rejection is less well studied.*Methods: We…
2019 American Transplant Congress
Metabolomic Study Of Sarcopenia In Patients Prior To Liver Transplantation
S. Ries,¹, N. J. Skill¹, E. Campbell¹, R. Daniel², C. A. Kubal¹, M. S. Richard¹, M. A. Maluccio¹
¹Surgery, Indiana University, Indianapolis, IN, ²University of Washington, Seattle, WA
*Purpose: Sarcopenia is defined as the loss of muscle mass, typically associated with aging, but frequently appearing in liver disease patients. In particular, sarcopenia present…
2019 American Transplant Congress
Pre-Transplant Multidimensional Flow Cytometric Analysis of Kidney Transplant Recipients Reveals Novel Immune Signature of Allograft Rejection
P. Schroder¹, J. S. Yi¹, K. J. Weinhold¹, C. Chan², M. Joshi³, C. Walters³, J. Kwun¹, S. J. Knechtle¹
¹Department of Surgery, Duke University Medical Center, Durham, NC, ²Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, ³Substrate Services Core and Research Support, Duke University Medical Center, Durham, NC
*Purpose: Multicolor flow cytometry and multiplex assay platforms have revolutionized immune cell phenotyping and functional analyses, but these powerful tools have not demonstrated clinically meaningful…
2019 American Transplant Congress
Impact of HLA Mismatches and Cytomegalovirus Seropositivity on Outcomes Following Heart Transplantation
A. Singhvi, R. Araujo-Gutierrez, M. H. Park, A. Bhimaraj, B. H. Trachtenberg, I. Hussain, A. Guha
Division of Cardiology/ JC Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX
*Purpose: Cytomegalovirus (CMV) infection is associated with the development of cardiac allograft vasculopathy (CAV). CAV is one of the leading causes of death and graft…
2019 American Transplant Congress
Mycophenolic Acid Area under the Curve Monitoring via Limited Sampling Strategy in Pediatric Heart Transplant Recipients
S. Crow, S. H. Dahl, J. N. Johnson
Mayo Clinic, Rochester, MN
*Purpose: The study aim was to investigate exposure to mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil (MMF), after pediatric orthotopic heart transplantation (pOHT).…