2019 American Transplant Congress
TDCA/Valine Reverse Obesity and Ameliorate Alloimmune Responses through a Decreased Hypothalamic Expression of MCH
1Brigham and Women's Hospital, Boston, AL, 2Beth Israel Deaconess Medical Center, Boston, AL
*Purpose: Obesity is associated with low grade inflammation and bariatric surgery is the only effective treatment in reducing excess weight both pre- and post-transplant.*Methods: Here,…2019 American Transplant Congress
The Evolving Clinical Presentation of Acute Rejection in Face Transplantation
Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Clinical signs such as erythema or edema are traditionally helpful to diagnose Acute rejection (AR) in face transplantation (FT) in the early follow-up. The…2019 American Transplant Congress
Cardiovascular Mortality in Transplant Patients; A Population-Based Cohort Study 1988-2013 in Australia and New Zealand
*Purpose: Transplant recipients experience excess cardiovascular morbidity and mortality. We compared cardiovascular death rates in kidney transplant recipients to the general population and identified risk…2019 American Transplant Congress
Expanding the Donor Pool with Extended Criteria DCD Livers
*Purpose: Utilization of extended criteria donation after circulatory death (ECD DCD) livers has remained cautious due to potentially worse outcomes because of higher rates of…2019 American Transplant Congress
High Numbers of Differentiated CD8+CD28– T Cells Are Associated with a Substantially Lowered Risk for Late Rejection and Graft Loss after Kidney Transplantation
Nephrology & Transplantation, Erasmus MC, Rotterdam, Netherlands
*Purpose: Recipients of a kidney transplant have a prematurely aged T-cell system. This is reflected in lowered thymic output, reduced telomere length and more highly…2019 American Transplant Congress
Treg And Bone Marrow Infusion Promotes Survival Of Donor Kidney Grafted Months After Disappearance Of Mixed Chimerism
Columbia Center for Translational Immunology, Columbia University, New York City, NY
*Purpose: Transient mixed chimerism induced with non-myeloablative conditioning in monkeys and humans induces tolerance to about 70% of donor kidney grafts transplanted at the time…2019 American Transplant Congress
Not All Donor-Specific Antibodies Are Equal: Predictors of Risk of Chronic Lung Allograft Dysfunction
*Purpose: Donor-specific HLA antibodies (DSA) have been previously associated with chronic lung allograft dysfunction (CLAD). However, the DSA characteristics that predict risk of CLAD are…2019 American Transplant Congress
Portal-endocrine And Gastric-exocrine Drainage Technique In Pancreatic Transplantation
Willis-Knighton Regional Transplant Center, Shreveport, LA
*Purpose: Pancreas Transplant (PTx) is an established treatment for patients with diabetes mellitus. Diagnosis of rejection has continued to be problematic. In 2007, a new…2019 American Transplant Congress
Quantifying Donor Effects on Transplant Outcomes Using Kidney Pairs from Deceased Donors
*Purpose: In kidney transplantation, the relative contribution of donor versus other factors on clinical outcomes is unknown.*Methods: For paired donations from deceased donors resulting in…2019 American Transplant Congress
Impact of Race and Substance Use on Listing Decisions for Kidney Transplant
*Purpose: Racial/ethnic minority patients face reduced access to kidney transplantation. We hypothesized that this disparity may be magnified if patients also have major psychosocial liabilities…
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