Am J Transplant, Volume 19, Suppl 3 Archives - Page 125 of 214 - ATC Abstracts

2019 American Transplant Congress
The Innsbruck Handtransplant Program: Eighteen Years of Experience
F. Messner, T. Hautz, A. Weissenbacher, S. Schneeberger
Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria
*Purpose: Reconstructive transplantation represents a therapeutic option for severe tissue defects which are not amendable to conventional reconstructive attempts. We herein report long-term follow-up data…
2019 American Transplant Congress
Mitochondrial Permeability Regulates Heart Graft Ischemia – Reperfusion Injury and Rejection
A. Qamar¹, J. Jiang¹, X. Huang², P. McLeod², A. M. Jevnikar², Z. Zhang²
¹Pathology and Laboratory Medicine, University of Western Ontario, London, ON, Canada, ²London Health Sciences Centre, London, ON, Canada
*Purpose: A growing body of evidence indicates that mitochondrial permeability transition pore (mPTP) formation plays a crucial role in necroptosis - a programmed form of…
2019 American Transplant Congress
Flow Cytometric Analysis of Leukocyte Migration during Ex Vivo Lung Perfusion with CXCR4 Inhibition
J. Yerxa¹, Q. Gao¹, R. P. Davis², M. Zhang¹, U. Scheuermann¹, W. Parker¹, M. G. Hartwig², A. Barbas¹
¹General Surgery, Duke University, Durham, NC, ²Thoracic Surgery, Duke University, Durham, NC
*Purpose: Ex vivo lung perfusion (EVLP) has emerged as a preservation technique utilized to evaluate candidate donor lungs in a metabolically active state. This also…
2019 American Transplant Congress
Evaluation of New Baskent University Preservation Solution for Liver, Kidney and Intestine Graft during Cold Ischemia: Preliminary Experimental Animal Study
M. Haberal¹, M. Kirnap¹, R. Erdem², H. Ozdemir³, M. Lux², D. Bacanli⁴
¹Transplantation, Baskent University, Ankara, Turkey, ²Pharmacology, Baskent University, Ankara, Turkey, ³Pathology, Baskent University, Ankara, Turkey, ⁴Experimental Laboratory, Baskent University, Ankara, Turkey
*Purpose: Despite significant advances in organ transplantation, damage caused to organs due to long cold ischemia time and perfusion solutions remains a serious hurdle. The…
2019 American Transplant Congress
A Prognostic Biomarker to Estimate the Likelihood of Developing De Novo Donor Specific Antibody in Kidney Transplant Recipients
S. Kawakita¹, L. M. Rebellato², K. P. Briley², A. Q. Maldonado³, C. E. Haisch², P. Bolin², S. A. Kendrick⁴, H. Jones⁴, K. McLawhorn⁴, D. Leeser², V. Jucaud¹, V. Burnett¹, M. J. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²East Carolina University, Greenville, NC, ³Vidant Medical Center, Greenville, NC, ⁴Eastern Nephrology Associates, Greenville, NC
*Purpose: Evaluation of human leukocyte antigen (HLA) mismatch at antibody epitope level rather than antigen level may explain better the impact of HLA mismatch on…
2019 American Transplant Congress
High Urinary Neutrophil Gelatinase Lipocalins (NGAL) Levels in Kidney Perfusates as Predictor of a Better Renal Function
A. Angeletti, C. Donadei, V. De Pace, I. Capelli, V. Corradetti, C. Zannini, F. Alviano, L. Bonsi, G. Comai, M. Ravaioli, G. La Manna
DIMES, S.Orsola-Malpighi Hospital, Bologna University, Bologna, Italy
*Purpose: Neutrophil gelatinase-associated lipocalin (NGAL) has recently emerged as a biomarker of different conditions, but the biological role remains unclear. We hypnotized that NGAL has…
2019 American Transplant Congress
Cell Coding Transcriptomic Analysis Of Serial Blood And Biopsy Samples In A Large Cohort Of Kidney Transplant Recipients
W. Zhang¹, Z. Yi¹, Z. Sun¹, K. Keung², C. Wei¹, C. Xi¹, S. Farouk¹, M. Menon¹, P. Cravedi¹, P. O'Connell², B. Murphy¹
¹Icahn School of Medicine at Mount Sinai, New York, NY, ²The University of Sydney, Sydney, Australia
*Purpose: Whole blood and graft biopsy RNA expression analyses are limited by the heterogeneous cell composition of the samples. Cell coding is an analytical tool…
2019 American Transplant Congress
Utilizing Imagestream Technology to Determine Hepatocellular CD38 Localization
Y. Lee, J. Kim, B. F. Reader, C. Akateh, K. R. Maynard, K. W. Washburn, J. L. Zweier, B. A. Whitson, S. M. Black
Department of Cardiac Surgery, The Ohio State Univ. Medical Center, Columbus, OH
*Purpose: CD38 is an ecto-enzyme that modulates intracellular calcium levels by producing potent secondary messengers, which utilize the cellular NAD pool and lead to increased…
2019 American Transplant Congress
CD56+CD57+ Infiltrate is a Predominant Subset of Infiltrating Natural Killer Cell in Renal Transplant Biopsies with Antibody-Mediated Rejection
H. Jung¹, Y. Wee², J. Kim², M. Choi², J. Choi², H. Kwon², J. Jung², S. Kim³, Y. Cho⁴, Y. Park⁴, H. Go⁴, M. Han⁵, Y. Kim², D. Han², S. Shin²
¹Department of Biomedical Science, Asan Medical Institute of Convergence Science and Technology (AMIST), Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ²Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ³Department of Convergence Medicine, Asan Institute for life sciences, Asan Medical Center, Seoul, Korea, Republic of, ⁴Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of, ⁵Department of Clinical Epidemiology, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: To verify a subset of intragraft and circulating natural killer cells associated with kidney allograft rejection and fibrosis.*Methods: Thirty-nine clinically indicated transplant biopsies performed…
2019 American Transplant Congress
Graft Survival of Fourth Time Renal Transplant Recipients Are Similar to Third Time Transplants: A SRTR Database Analysis
B. Petrun, R. Nygaard, M. Hill, C. Richardson, A. Israni, P. Stahler
Hennepin County Medical Center, Minneapolis, MN
*Purpose: The number of candidates for repeat kidney transplant in the United States has steadily increased over the last 30 years. Second and third kidney…