2019 American Transplant Congress
Multiplexed Droplet Single-Cell RNA-Sequencing for Cellular Profiling of Transplant Rejection
Department of Surgery, UCSF, San Francisco, CA
*Purpose: Multiplexed droplet single-cell RNA-sequencing (mdscRNA-seq) has been utilized across many tissue types for fast and paralleled transcriptomic profiling. However, maintaining sample identity for differential…2019 American Transplant Congress
Gut Microbiome And Acute Rejection After Kidney Transplantation
*Purpose: Acute rejection (AR) is a common complication in kidney transplantation (KT) and associated with reduced patient-graft survival. Recent studies have shown that the gut…2019 American Transplant Congress
Iguratimod Attenuates the Production of Donor Specific Antibody by Inducing CD19+Tim-1+ Regulatory B Cells and Imbalance of Th17 Treg
No.300 Guangzhou Road of Nanjing, Nanjing, China
*Purpose: This study was designed to investigate the effect and mechanisms of Iguratimod on circulating DSA and allograft survival in a skin transplant model.*Methods: Mice…2019 American Transplant Congress
Characterization of Innate Lymphoid Cells in Full Facial and Limb Transplant Recipients
*Purpose: Vascular composite allotransplantation (VCA) transplantation is a life-transforming procedure with encouraging results. Despite the recent advances, the immunological response in these patients is still…2019 American Transplant Congress
Heterozygous Gene Mutations In The Complement Factor I (cfi) Was Susceptibility Gene For The C3 Glomerulonephritis In Native Kidney And Renal Allograft
*Purpose: We previously reported heterozygous c.848A > G and c.1339C > T gene mutations in the complement factor I (CFI) gene (NM_000204.3) in a kidney transplant recipient with C3…2019 American Transplant Congress
Indocyanine Green Fluorescence Imaging during Normothermic Ex Vivo Liver Perfusion for the Assessment of Hepatocyte, Biliary, and Vascular Function
Multi-Organ Transplant Program, Department of Surgery, Toronto General Hospital, Toronto, ON, Canada
*Purpose: Normothermic Ex Vivo Liver Perfusion (NEVLP) is a novel preservation for the storage and assessment of marginal grafts, such as Donation after Cardio-circulatory Death…2019 American Transplant Congress
Inhibition of Cyclin-Dependent Kinase 2 Signaling Prevents Liver Ischemia and Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Hepatic ischemia/reperfusion injury (IRI), an exogenous antigen-independent local inflammation response, occurs in multiple clinical settings including liver transplantation, hepatic resection, trauma, and shock. The…2019 American Transplant Congress
Pancreatic Extracellular Matrix Improves Human Islet Culture and Function In Vitro
Virginia Commonwealth University, Richmond, VA
*Purpose: Islet transplantation is a thriving therapy for patients with Chronic Pancreatitis and Type-1 Diabetes. Within the pancreas, the islets are surrounded by Extracellular Matrix…2019 American Transplant Congress
Predicting Post-Transplant Graft Function in Deceased Donor Kidney Transplant Recipients
*Purpose: Discarding donor organs lengthens time patients spend on the kidney transplant (KT) wait list. To identify characteristics associated with short-term outcome in deceased donor…2019 American Transplant Congress
Liquid Biopsy for Chronic Rejection after Kidney Transplantation. A Novel Non-Invasive Biomarker Involved in Inflammatory Amplifier
*Purpose: In kidney transplantation (KTx), despite recent advances of medical technology, chronic rejection accounts for 25% of the graft loss. Chronic active antibody-mediated rejection (CAAMR)…
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