Am J Transplant, Volume 19, Suppl 3 Archives - Page 123 of 214 - ATC Abstracts

2019 American Transplant Congress
Cardiovascular Mortality in Transplant Patients; A Population-Based Cohort Study 1988-2013 in Australia and New Zealand
M. Wyld¹, N. De La Mata², P. Masson³, E. O'Lone², A. Webster²
¹Renal Department, Royal Prince Alfred Hospital, Camperdown, Australia, ²School of Public Health, University of Sydney, Sydney, Australia, ³Renal Department, Royal Free London NHS Foundation Trust, London, United Kingdom
*Purpose: Transplant recipients experience excess cardiovascular morbidity and mortality. We compared cardiovascular death rates in kidney transplant recipients to the general population and identified risk…
2019 American Transplant Congress
Expanding the Donor Pool with Extended Criteria DCD Livers
P. Mihaylov¹, B. Ekser², R. Mangus², J. Fridell², D. Soma², C. Kubal²
¹Indiana Univ School of Medicine, Pavia Univ School of Medicine, Indianapolis, IN, ²Indiana Univ School of Medicine, Indianapolis, IN
*Purpose: Utilization of extended criteria donation after circulatory death (ECD DCD) livers has remained cautious due to potentially worse outcomes because of higher rates of…
2019 American Transplant Congress
High Numbers of Differentiated CD8⁺CD28^– T Cells Are Associated with a Substantially Lowered Risk for Late Rejection and Graft Loss after Kidney Transplantation
M. G. Betjes, A. Langerak, M. Klepper, N. Litjens
Nephrology & Transplantation, Erasmus MC, Rotterdam, Netherlands
*Purpose: Recipients of a kidney transplant have a prematurely aged T-cell system. This is reflected in lowered thymic output, reduced telomere length and more highly…
2019 American Transplant Congress
Treg And Bone Marrow Infusion Promotes Survival Of Donor Kidney Grafted Months After Disappearance Of Mixed Chimerism
K. Bruestle, P. Alonso-Guallart, E. Lopes, G. Pierre, N. Llore, H. Sakai, S. Kofman, D. Ekanayake-Alper, M. Sykes, A. Griesemer
Columbia Center for Translational Immunology, Columbia University, New York City, NY
*Purpose: Transient mixed chimerism induced with non-myeloablative conditioning in monkeys and humans induces tolerance to about 70% of donor kidney grafts transplanted at the time…
2019 American Transplant Congress
Not All Donor-Specific Antibodies Are Equal: Predictors of Risk of Chronic Lung Allograft Dysfunction
C. J. Iasella¹, C. R. Ensor², M. Marrari³, M. Mangiola³, C. A. Moore¹, M. R. Morrell⁴, J. Pilewski⁴, J. F. McDyer⁴, A. Zeevi³
¹Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA, ²Florida Hospital Transplant Institute, AdventHealth Orlando, Orlando, FL, ³Pathology, University of Pittsburgh, Pittsburgh, PA, ⁴Medicine, University of Pittsburgh, Pittsburgh, PA
*Purpose: Donor-specific HLA antibodies (DSA) have been previously associated with chronic lung allograft dysfunction (CLAD). However, the DSA characteristics that predict risk of CLAD are…
2019 American Transplant Congress
Portal-endocrine And Gastric-exocrine Drainage Technique In Pancreatic Transplantation
G. Zibari, B. Samant, R. McMillan, N. Singh, H. Shokouh-Amiri
Willis-Knighton Regional Transplant Center, Shreveport, LA
*Purpose: Pancreas Transplant (PTx) is an established treatment for patients with diabetes mellitus. Diagnosis of rejection has continued to be problematic. In 2007, a new…
2019 American Transplant Congress
Quantifying Donor Effects on Transplant Outcomes Using Kidney Pairs from Deceased Donors
K. F. Kerr¹, E. R. Morenz¹, H. Thiessen Philbrook², S. G. Coca³, F. P. Wilson⁴, P. P. Reese⁵, C. R. Parikh²
¹University of Washington, Seattle, WA, ²Johns Hopkins University, Baltimore, MD, ³Icahn School of Medicine at Mount Sinai, New York, NY, ⁴Yale University, New Haven, CT, ⁵University of Pennsylvania, Philadelphia, PA
*Purpose: In kidney transplantation, the relative contribution of donor versus other factors on clinical outcomes is unknown.*Methods: For paired donations from deceased donors resulting in…
2019 American Transplant Congress
Impact of Race and Substance Use on Listing Decisions for Kidney Transplant
R. N. DeBlasio¹, L. Myaskovsky², K. Kendall¹, A. DiMartini¹, G. Switzer¹, D. M. Posluszny¹, C. Puttarajappa¹, A. D. Tevar¹, S. Hariharan¹, R. Shapiro³, M. A. Dew¹
¹U Pittsburgh, Pittsburgh, PA, ²U New Mexico, Albuquerque, NM, ³Mt Sinai Recanati/Miller Transplantation Institute, New York, NY
*Purpose: Racial/ethnic minority patients face reduced access to kidney transplantation. We hypothesized that this disparity may be magnified if patients also have major psychosocial liabilities…
2019 American Transplant Congress
Difficult Outflow Reconstruction Using Eptfe Vascular Grafts In Ldlt: Technical Innovations And Outcomes.
A. Thorat¹, L. Jeng², P. Li², S. Hsu², H. Yang², C. Yeh², T. Chen², K. Poon²
¹China Medical University Hospital, Taichung, Taiwan, ²Organ Transplantation Center, China Medical University Hospital, Taichung, Taiwan
*Purpose: Right liver allograft is a partial graft and hence, backtable reconstruction of undrained segments is crucial to increase the functional liver mass. Undrained segments…
2019 American Transplant Congress
Correlation of Donor-Derived Cell-Free DNA with Histology and Molecular Diagnoses of Kidney Transplant Biopsies
I. Moinuddin¹, D. Kumar¹, P. Halloran², L. Kamal¹, A. King¹, P. Kimball¹, M. Levy¹, C. Bhati¹, D. Massey¹, G. Gupta¹
¹VCU Medical Center, Richmond, VA, ²Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Circulating donor-derived cell free DNA (cfDNA; Allosure, CareDx, USA), a non-invasive test that could detect rejection in kidney allografts was validated using histologic diagnoses(HDx).…