ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Variation in Racial Disparities in Liver Transplant Outcomes by Hospital Quality

    K. Ross, R. Patzer, R. Lynch

    Emory University, Emory Transplant Center, Atlanta, GA

    *Purpose: Black patients experience inferior outcomes after liver transplant (LTx). Studies of other outcomes have shown that disparities are partially attributable to variation in quality…
  • 2019 American Transplant Congress

    Increasing Time-in-Therapeutic Range of Tacrolimus is Associated with Superior Outcomes in Living Kidney Transplants

    T. Lin, T. Song, S. Yin, Y. Jiang, Z. Huang, X. Wang, J. Liu, Z. Wang

    Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China

    *Purpose: Tacrolimus-based regimens remain the backbone of maintenance immunosuppressive therapy in kidney transplant, and therapeutic drug monitoring of tacrolimus is necessary due to a narrow…
  • 2019 American Transplant Congress

    Positron Emission Tomography (PET-CT) Global Coronary Flow Reserve (CFR) Stratifies Cardiovascular Risk among Renal Transplant (RTx) Candidates

    M. Minder, S. Mason, J. Ethington, R. McCubrey, D. Min, N. Sekaran, J. Orford, D. Morris, S. Anand, T. Srinivas

    Intermountain Healthcare, Murray, UT

    *Purpose: Chronic kidney disease (CKD) and diabetes (DM) are both associated with increased risk of coronary artery disease and Major Adverse Cardiovascular Events (MACE). The…
  • 2019 American Transplant Congress

    Chronic Kidney Disease among Liver Transplant Candidates: A Rising Burden and Its Impact on Post-Liver Transplant Outcomes

    G. Cullaro1, E. C. Verna2, B. P. Lee1, J. C. Lai1

    1UCSF, San Francisco, CA, 2Columbia University, New York, NY

    *Purpose: Chronic kidney disease (CKD) is the end manifestation of persistent renal damage, a pathology distinct from the reversible acute kidney injury (AKI). This distinction…
  • 2019 American Transplant Congress

    TIPS Effectively Treats Refractory Hepatic Hydrothorax: A Multi-Center U.S. Retrospective Study of 1,260 Patients

    M. German1, A. Lee1, A. Hristov1, A. Said1, J. Boike2, J. Ge3, N. Jest4, G. Morelli4, K. Kolli3, J. Lai3, A. Desai5, S. Junna6, B. Pokhrel6, T. Couri7, S. Paul7, C. Frenette8, N. Christian-Miller8, E. Verna9, U. Rahim10, A. Goel10, A. Das2, S. Pine2, D. Gregory2, L. VanWagner2, E. Spengler1

    1University of Wisconsin, Madison, WI, 2Northwestern University, Chicago, IL, 3University of California, San Francisco, San Francisco, CA, 4University of Florida, Gainesville, FL, 5University of Indiana, Indianapolis, IN, 6University of Arizona, Tucson, AZ, 7University of Chicago, Chicago, IL, 8Scripps Clinic, San Diego, CA, 9Columbia University, New York, NY, 10Stanford University, Palo Alto, CA

    *Purpose: Hepatic hydrothorax (HHT) occurs in 5-10% of patients with cirrhosis. Current literature on the use of transjugular intrahepatic portosystemic shunt (TIPS) in the treatment…
  • 2019 American Transplant Congress

    Optimal Timing of Hepatitis C Treatment among HIV/HCV Co-Infected End-Stage Renal Disease Patients: Pre vs. Post-Transplant

    B. Shelton1, G. Berdahl1, D. Sawinski2, B. Linas3, P. Reese2, M. Mustian1, R. Reed1, P. MacLennan1, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 3Boston University School of Medicine, Boston, MA

    *Purpose: End-stage renal disease (ESRD) patients co-infected with HCV and HIV have access to effective treatment options for HCV infection. However, they also have access…
  • 2019 American Transplant Congress

    miR-20a Inhibits Autophagy by Targeting AKT and BIM in Renal Reperfusion Injury

    T. Lin, T. Song, Y. Jiang, J. Liu, Z. Wang, L. Li, Z. Huang, Y. Fan, X. Wang

    Organ Transplantation Center, Urology Department, Urology Research Institute, WestChina Hospital, Sichuan University, Chengdu, China

    *Purpose: Previously, we found up-regulation of miR-20a after kidney ischemia reperfusion (I/R) injury and may serves as a protector; however, its specific mechanism remains unclear.Autophagy…
  • 2019 American Transplant Congress

    Racial and Income-Based Disparities in Access to Kidney Transplantation in the Context of a Nationally-Financed Health System in Brazil

    A. Saha1, G. Ferreira2, Y. Yu1, M. Waldram1, V. Colares2, J. Bastos2, M. Henderson1, D. Segev1, A. Massie1

    1Surgery, Johns Hopkins School of Medicine, Baltimore, MD, 2Santa Casa de Misericordia de Juiz de Fora, Juiz de Fora, Brazil

    *Purpose: Changes in economic and social factors in low- and middle-income countries have led to rising burden of chronic disease. Brazil, a middle-income country with…
  • 2019 American Transplant Congress

    T Cell Repertoire of Tissue Infiltrating T-cells at Time of Rejection

    R. Reindl-Schwaighofer1, J. Vetter2, J. Weinberger3, S. Schaller2, A. Heinzel1, G. Gualdoni1, C. Aschauer1, K. Jelencsics1, K. Hu1, S. Winkler2, R. Oberbauer1

    1Nephrology, Medical University of Vienna, Vienna, Austria, 2University of Applied Sciences Upper Austria, Hagenberg, Austria, 3Austrian Red Cross, Vienna, Austria

    *Purpose: Tissue infiltration of T-cells is the hallmark of acute cellular graft rejection. Next generation sequencing of T-cell receptors enables in depth analysis of the…
  • 2019 American Transplant Congress

    BTLA Suppressed Acute Rejection by Regulating T Cell Receptor Downstream Signal Pathways and Cytokine Production in Renal Transplant and Contributed to Prolongation of Allograft Survival

    J. Zhang, Z. Wang, S. Fei, H. Chen, L. Sun, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu

    No.300 Guangzhou Road of Nanjing, Nanjing, China

    *Purpose: The present study aimed to investigate the role of BTLA in the progress of acute rejection after kidney transplantation.*Methods: In human allograft renal transplanted…
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