2018 American Transplant Congress
Whole-Transcriptome Sequencing to Identify Macaque Immune Gene Variants
Macaque monkeys are critical in transplantation studies, yet macaque genomics lags significantly behind human genomics. While reliable genotyping methods have been developed for some macaque…2018 American Transplant Congress
Soluble Fibrinogen-Like Protein 2 Regulates Myeloid-Derived Suppressor Cells Differentiation and Enhances Its Immunosuppressive Function of in Allograft Immunity
Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Soluble fibrinogen-like protein 2 (sFGL2) is a novel immunoregulatory molecule, secreted mainly by regulatory T cells. CD11b+ Gr1+ myeloid-derived suppressor cells (MDSCs) are an important…2018 American Transplant Congress
Influence of X-Ray Repair Cross-Complementing Group (XRCC) Genes Polymorphisms on the Development of Antibody-Mediated Rejection (ABMR) in Renal Transplant Recipients
The importance of antibody-mediated rejection (ABMR) on the renal transplant recipients has been recognized in recent years. However, the pathogenesis of ABMR following kidney transplantation…2018 American Transplant Congress
Eluates from Fine-Needle Allograft Biopsy Increase Donor-Specific Antibody Identification in Antibody Mediated Rejection
1University of Cincinnati, Cincinnati; 2Hoxworth Blood Center, Cincinnati.
Aim. Antibody mediated rejection (AMR) represents a risk for graft loss, and the presence of circulating donor-specific antibody (cDSA) is a major criterion for AMR…2018 American Transplant Congress
Impact of De Novo DSA (DnDSA) on Outcomes in HLA-Sensitized (HS) Patients Transplanted after IVIG + Rituximab Desensitization (DES)
Introduction: Highly-HLA sensitized patients (HS) with donor specific antibodies (DSA) at transplant are at risk for Type 1 ABMR. However, the incidence of Type 2…2018 American Transplant Congress
Impact of Bw4 and Bw6 Epitope Mismatch on Clinical Outcomes after Renal Transplantation
HLA class II epitope mismatch has been shown to impact the long-term survival of kidney allografts. HLA-B alleles are traditionally grouped by the Bw4 and…2018 American Transplant Congress
Pre-Emptive Rituximab and Intravenous Immunoglobulin (IVIg) Fail to Prevent Rejection in Kidney Transplant Recipients (KTx) with Donor Specific Antibodies (DSA)
Columbia University, New York, NY.
Introduction:IVIg and Rituximab have been used successfully to improve transplantation rates in sensitized patients. DSA detected by Flow crossmatch (FXM+) or Luminex® at time of…2018 American Transplant Congress
Standard- versus Low-Dose Valganciclovir for Cytomegalovirus Prophylaxis in Intermediate-Risk Kidney Transplant Recipients
Henry Ford Hospital, Detroit, MI.
Background: Although guidelines recommend valganciclovir (VGC) 900 mg daily for cytomegalovirus (CMV) prophylaxis in solid organ transplant patients, multiple centers have reported clinical success, reduced…2018 American Transplant Congress
Retrospective Study of Cryptococcosis in Kidney Transplant Recipients from a Single Center
Background: The mortality of Cryptococcosis remains unchanged among kidney transplant recipients(KTR) over the past two decades, and the prognosis of Cryptococcosis is yet unpredicted. Hence,…2018 American Transplant Congress
Effect of Everolimus on Body Composition; 1-Year after Kidney Transplantation
【Background】Weight gain, and especially visceral fat gain early after kidney transplantation has a worse outcome for metabolic disorder, graft function, and cardiovascular disease. The mammalian…
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