Am J Transplant, Volume 18, Suppl 3 Archives - Page 92 of 211 - ATC Abstracts

2018 American Transplant Congress
A Comparison of the Discard Rate in Hepatitis C Deceased Liver Donors between Two Eras, 2008-2013 and 2014-2017. A Single Organ Procurement Organization Experience
M. Nazzal,¹ G. Marklin,² O. Okoye,¹ Y. Kim,¹ R. Ouseph.¹
¹Abdominal Transplant, Saint Louis University, Saint Louis, MO; ²Mid America Transplant, Saint Louis, MO.
With the introduction of new hepatitis C medications in 2014 , there is a growing concern for an increase in the discard rate of hepatitis…
2018 American Transplant Congress
Corner-Saving Renal Artery Anastomosis for Renal Transplantation
A. Akdur,¹ M. Kus,² G. Moray,¹ S. Yildirim,¹ F. Yarbug Karakayali,³ K. Caliskan,² M. Haberal.¹
¹Transplantation, Baskent University, Ankara, Turkey; ²Transplantation, Baskent University, Adana, Turkey; ³Transplantation, Baskent University, Istanbul, Turkey.
Introduction: Renal transplantation is the preferred treatment for most patients with end-stage renal disease. Postoperative vascular complications that significantly affect graft loss include renal artery…
2018 American Transplant Congress
Bone Marrow Derived Myeloid Suppressor Cell (BM-MDSCs) Prolongs the Graft Survival in Murine Heart Transplantation
K. Uchida, K. Fujimoto, K. Takeda, H. Bashuda, E. Yin, K. Okumura.
Atopy(Allergy) Research Center, Juntento University, Tokyo, Japan.
Purpose: To investigate the impact of BM-MDSCs on murine heart transplantationMaterial and Methods:Bone marrow cells were harvested and cultured with granulocyte-macrophage colony-stimulating factor (GM-CSF) and…
2018 American Transplant Congress
Hypothermic Machine Perfusion Protects DCD Liver Graft through Metabolism of Xenobiotics by Cytochrome P450 Pathway
Q. Ye,^1,2 W. Liang,¹ Z. Zhong,¹ S. Ye,¹ B. Tang,¹ Q. Hu,¹ J. Liang,¹ Y. Wang.¹
¹Transplant Center of Wuhan University, Zhongnan Hospital of Wuhan University, Wuhan, China; ²The 3rd Xiangya Hospital of Central South Unversity, Changsha, China.
Background: Donation after cardiac death (DCD) is the mainly resource to relieve organ-transplantation shortage. Our previous research have confirmed that the function of DCD liver…
2018 American Transplant Congress
Glycolytic Bias in mTORC2-Deficient Dendritic Cells Potentiates Antigen-Specific Immunity and Accelerates Graft Rejection
A. Watson,¹ H. Dai,¹ J. Diaz-Perez,² A. Menk,³ M. Killeen,² G. Delgoffe,³ A. Mathers,² A. Thomson.¹
¹Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ²Dermatology, University of Pittsburgh, Pittsburgh, PA; ³Cancer Institute, University of Pittsburgh, Pittsburgh, PA.
The mechanistic target of rapamycin (mTOR) is known to function in two complexes: mTOR complex 1 (mTORC1) and mTORC2. While the function of mTORC1 in…
2018 American Transplant Congress
mRNA Transcript Profiles of 14 Genes in Plasma Exosome Predict Risk for Antibody-Mediated Rejection (ABMR) of Renal Allografts
H. Zhang,¹ E. Huang,² C. Nast,³ J. Kahwaji,² A. Vo,² S. Jordan,² M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ³Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Previously we reported that mRNA transcript profiles of 4 genes (gp130, SH2D1B, TNFα and CCL4) in plasma exosome could predict the risk of ABMR,…
2018 American Transplant Congress
Investigation of Lower Treatment Failure Rate Seen among Black Kidney Recipients on LCP-Tacrolimus vs. IR-Tacrolimus: Subgroup Analyses of Two Phase 3 Trials
T. Sparkes,¹ B. Masters,¹ C. Staino,² S. Patel,² M. Cooper.³
¹University of Maryland, Baltimore, MD; ²Veloxis, Cary, NC; ³Medstar Georgetown Transplant Institute, Washington, DC.
Black kidney transplant recipients are recognized as high risk for inferior allograft survival due to immunologic and non-immunologic factors. Pooled data from 2 Phase 3…
2018 American Transplant Congress
Inferior Patient and Graft Survival in Highly Sensitized Adult Kidney Transplant Recipients with a Prior Transplant Compared to Pediatric Kidney Transplant Recipients: An Analysis of OPTN Data
P. Almond,¹ S. Al-Akash,¹ D. Stewart,² A. Robinson.²
¹CPSST Departments of Pediatric Surgery and Renal Transplantation, Driscoll Children's Hospital, Corpus Christi, TX; ²UNOS, Richmond, VA.
Under the current kidney allocation system (KAS), pediatric (PED) renal transplant (RTx) candidates have a priority to kidneys from KDPI <35% donors. However, that excludes…
2018 American Transplant Congress
Intestinal Microbiome Diversity is Associated with Liver Disease Etiology and Predicts Post-Liver Transplant Mortality
E. Verna, M. Annavajhala, M. Nenad, R. Brown, S. Sullivan, G. Korakani, M. Gidins, S. Khan, A. Gomez-Simmonds, A-.C. Uhlemann.
Medicine, Columbia University, New York, NY.
Background: Dysbiosis of the intestinal microbiome is common among patients with decompensated liver disease and has been associated with disease progression as well as life-threatening…
2018 American Transplant Congress
Comparison of Induction and Maintenance Immunosuppression Regimens in Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Registry
S. Nagai,¹ M. Rizzari,¹ Y. Muszkat,² K. Collins,¹ A. Yoshida,¹ S-.M. Jafri,² M. Abouljoud.¹
¹Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; ²Gastroenterology, Henry Ford Hospital, Detroit, MI.
Aim: Induction and maintenance immunosuppression regimens in intestinal transplant widely vary among centers. The aim of this study was to investigate an association between immunosuppression…