2018 American Transplant Congress
Organ Donation and Transplantation in US States and Europe – Is There a Benefit to Opting Out?
European reports suggest improved transplant rates in countries with Opt-out or presumed consent donation. Legislation to adopt Opt-out donation has been introduced in several US…2018 American Transplant Congress
Barriers and Disparities in Listing for Pediatric Solid Organ Transplant
Purpose The WHO recommends equitable access to transplant, yet disparities in listing based on gender, race, and education exist in adults. There is little research…2018 American Transplant Congress
DAP12 and Its Triggering Co-Receptor TREM2 Play Key Roles in Regulation of Mouse and Human Liver DC Function and Control of Liver Ischemia-Reperfusion Injury
Background: Liver interstitial dendritic cells (DCs) have been implicated in the control of liver ischemia/reperfusion injury (IRI) and in the induction of liver transplant tolerance.…2018 American Transplant Congress
Predicting Survival after Deceased-Donor Kidney Transplants by Donor-Recipient Match: Who Can Tolerate a High-KDPI Kidney?
Johns Hopkins School of Medicine, Baltimore, MD.
Deceased-donor kidney transplantation (DDKT) with high-KDPI kidneys carries an additional risk of mortality and graft failure, which could be tolerable for some candidates but detrimental…2018 American Transplant Congress
Transplantation of Kidneys from Hepatitis C Virus (HCV) Antibody (Ab) Positive, NAT Negative Donors to HCV Negative Patients Results in Seroconversion but Not Viral Transmission
Transplant Surgery, Loma Linda University Health, Loma Linda, CA.
Anecdotal reports have suggested that transplantation of HCV Ab+/NAT- donor kidneys into HCV negative recipients is safe and not associated with HCV transmission. With the…2018 American Transplant Congress
Endothelin-1 Type A Receptor Antibodies Are Associated with Elevated Il-8, Arteritis and Decline in Renal Function in Pediatric Renal Transplant Recipients
1University of California, Los Angeles, Los Angeles, CA; 2Duke University, Durham, NC.
Background: We have recently shown that the non-HLA antibody, AT1R-Ab, is prevalent and associated with poor outcomes in pediatric kidney transplant recipients (KTRs). The prevalence…2018 American Transplant Congress
Impact of Changes to the LAS Calculation
Purpose: On 2/19/2015 major revisions to the Lung Allocation Score (LAS) calculation were made to more appropriately reflect candidates' waiting list urgency and post-transplant survival.…2018 American Transplant Congress
hEPCR.hTBM.hCD47.HO-1 Contributes to Increased Survival, Reduced Platelet Sequestration, and Modulation of Coagulation Activation in GalTKO.hCD46 Porcine Livers Perfused with Human Blood
1University of Maryland School of Medicine, Baltimore, MD; 2Revivicor, Inc., Baltimore, MD.
IntroductionPlatelet sequestration and inappropriate coagulation cascade activation are associated with poor outcomes in multiple liver xenotransplant models. Here we evaluate a cassette of additional genetic…2018 American Transplant Congress
Redo Kidney Transplant in FSGS
Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, Washington, DC.
Objective: Analyze risk of graft failure due to recurrent FSGS in patients with prior failed kidney transplants under consideration for a subsequent transplant.Results: We identified…2018 American Transplant Congress
Cannabis Dependence or Abuse before and after Kidney Transplantation: Implications for Post-Transplant Outcomes
Currently, transplant centers vary in screening practices for marijuana use and requirements for abstinence before kidney transplantationWe examined billing claims and linked SRTR data for…
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