ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Parsing the 100% CPRA Kidney Transplant Candidates, Who Gets Transplanted?

    D. Keith.

    Medicine, Sacred Heart Hospital, Pensacola, FL.

    Currently the United States kidney allocation system gives priority to candidates with a CPRA of 100% by giving them additional allocation points and providing national…
  • 2018 American Transplant Congress

    Cell Free DNA Sequencing for Diagnosing Infections, Estimating Growth Rates, and Characterizing Antibiotic Resistomes in Urine Supernatants

    J. Lee,1 P. Burnham,2 D. Dadhania,1 M. Heyang,2 F. Chen,2 M. Suthanthiran,1 I. De Vlaminck.2

    1Weill Cornell Medicine, New York, NY; 2Cornell University, Ithaca, NY.

    INTRODUCTION. We examined the utility of cell-free DNA (cfDNA) sequencing of urine supernatants in kidney transplant recipients for diagnosing rare and common urinary tract infections…
  • 2018 American Transplant Congress

    Early Microcirculation Inflammation Associated with TCMR Leads to Poor Graft Outcomes in Kidney Transplant Recipients (KTRs)

    A. Cherukuri, D. Chittka, R. Mehta, A. Sharma, P. Sood, S. Hariharan.

    UPMC, Pittsburgh.

    Renal allograft microcirculation inflammation (MI) lesions including glomerulitis (g) and peritubular capillaritis (ptc) are associated with AMR and poor outcomes. The significance of MI lesions…
  • 2018 American Transplant Congress

    Liver Transplantation Using Pediatric versus Adult Donor Grafts in Adult Recipients

    Y. Tang, Q. Zhao, Z. Zhang, L. Wang, W. Ju, Z. Zhu, S. Huang, Z. Guo, X. He, G. Chen.

    Organ Transplant Center, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Background and Aim: The reported outcomes of adult liver transplantation using pediatric allografts are largely controversial based on single center studies. We aimed to compare…
  • 2018 American Transplant Congress

    CD4 T Cells Require Both S1PR1 and S1PR4 for Afferent Lymphatic Migration

    Y. Xiong,1 W. Piao,1 C. Brinkman,1 L. Li,1 J. Kulinski,2 A. Olivera,2 A. Cartier,3 T. Hla,3 S. Schwab,4 K. Hippen,5 B. Blazar,5 J. Bromberg.1

    1UMB, MD; 2NIH, MD; 3Boston Children's Hospital, MA; 4NYU, NY; 5U. Minnesota, MN.

    Introduction: Sphingosine 1-phospate (S1P) receptor 1 (S1PR1) drives T cell migration from thymus into blood, and lymph nodes (LN) into efferent lymphatics. Whether S1PR1 and…
  • 2018 American Transplant Congress

    Ex Vivo-Expanded Human CD19+CD73–CD25+CD71+TIM-1+ B Regulatory Cells Can Prolong Allograft Survival in a Humanized Mouse Model of Skin Transplantation and Are Dependent on TIM-1-Mediated Regulation of STAT3 Signaling

    S. Shankar,1 J. Stolp,1,2 S. Juvet,1,3 J. Hester,1 K. Wood.1

    1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 2Garvan Institute of Medical Research, Sydney, Australia; 3Toronto General Hospital Research Institute, Toronto, Canada.

    The importance of B regulatory cells (Breg) in both health and disease has rapidly become evident over the last decade. Breg are able to control…
  • 2018 American Transplant Congress

    Outcome of Second Kidney Transplantation According to Previous Pediatric Donor Type: A Retrospective Cohort Analysis

    K. Phonphok, T. Duong, S. Panombualert, S. Bunnapradist.

    Medicine-Nephrology, UCLA, Los Angeles, CA.

    Background: With the prioritization of age ≤ 18 years old at the time of registration on the kidney transplant waiting list in the United States,…
  • 2018 American Transplant Congress

    Dialysis Modality, Inflammation, and Frailty in Kidney Transplant Candidates

    P. Shrestha, H. Ying, M. McAdams DeMarco, D. Segev.

    JHU, Baltimore, MD.

    Inflammation is associated with poor physical performance, frailty, disability and death in community-dwelling older adults. Given the elevated inflammation levels among ESRD patients, it is…
  • 2018 American Transplant Congress

    The Feasibility of Laparoscopic Living Donor Right Hepatectomy Compared to Open Surgery Including 100 Laparoscopic Cases

    J. Rhu, G. Choi, J. Kim, J. Joh, C. Kwon, S. Kim.

    Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.

    Background: We designed this study to analyze the feasibility of laparoscopic living donor hepatectomy by comparing to open living donor hepatectomy.Methods : Living donors who…
  • 2018 American Transplant Congress

    Heart and Lung Transplantation Outcomes in HIV-Positive Recipients

    C. Koval,1 M. Malinis,2 N. Mueller,3 J. Krisl,4 M. Hannan,5 P. Grossi,6 S. Huprikar.7

    1Infectious Diseases, Cleveland Clinic, Cleveland, OH; 2Infectious Diseases, Yale University, New Haven, CT; 3Infectious Diseases, University Hospital Zurich, Zurich, Switzerland; 4Pharmacy, Houston Methodist Hospital, Houston, TX; 5Infectious Diseases, Mater Hospital, Dublin, Ireland; 6Infectious Diseases, University Insubria, Varese, Italy; 7Infectious Diseases, Mount Sinai Hospital, New York, NY.

    Purpose: Data for HIV+ patients receiving heart (HT) or lung transplantation (LT) are limited but appear to demonstrate acceptable outcomes. We aimed to add to…
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