ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    The Study of the Influence on hIAPP Deposition and Dysfunction in INS-1 Cell by Calcineurin Inhibitors

    J. Zhang, W. Lv, C. Zhang, N. Sun, X. Li, Y. Shi, A. Jiao, J. Lin, Y. Lv.

    Hepatobiliary Surgery Department and Unit of Organ Transplantation, The First Hospital of China Medical University, Shenyang, Liaoning, China.

    Background hIAPP is formed in islet β cells, misfolded hIAPP results in the deposition inside the β-cells and shows a damage to the β-cells. The…
  • 2018 American Transplant Congress

    Non-Immunologic Pairing of Kidney Transplant Donors and Recipients: How Important is HLA Match Status?

    A. Miller, B. Kiberd, K. Tennankore.

    Division of Nephrology, Department of Medicine, Dalhousie University, Halifax, NS, Canada.

    Currently, allocation preference in deceased donor kidney transplantation is given to donors and recipients (D/R) with 0 human leukocyte antigen (HLA) mismatches (MM), with non-immunologic…
  • 2018 American Transplant Congress

    A Calculated Panel Reactive Antibody (CPRA) Calculator Supporting Both Allele-Level and Antigen-Level HLA Specificities

    L. Gragert,1,2 E. Kransdorf,3 N. Kaur,1 M. Maiers,2 J. Kobashigawa,3 M. Pando.4

    1Tulane University School of Medicine, New Orleans; 2National Marrow Donor Program / Be The Match, Minneapolis; 3Cedars-Sinai Heart Institute, Los Angeles; 4Baylor Scott and White, Temple.

    Introduction:The number of HLA alleles represented on Luminex assays has increased over time, allowing for improved characterization of anti-HLA antibody specificity. Calculated Panel Reactive Antibody…
  • 2018 American Transplant Congress

    Effect of rATG on Monocytic Myeloid-Derived Suppressor Cells and Its Associated Mechanisms in Kidney Transplantation Recipients

    Y. Jiang, X. Zhang.

    Beijing Chao-Yang Hospital, Beijing, China.

    Myeloid-derived suppressor cells (MDSCs) consist of heterogeneous myeloid progenitors and precursors that was first defined in cancer patients and are characterized by a regulatory ability…
  • 2018 American Transplant Congress

    Risk of Bacteremia According to Transplant Induction Immunosuppression Regimen

    E. Misch, S. Kelley, G. Leverson, B. Astor, D. Kaufman.

    University of Wisconsin School of Medicine and Public Health, Madison.

    Background: Transplant immune suppression is designed to suppress the adaptive immune response and ensure graft survival, but may have unintended effects on innate immunity. Few…
  • 2018 American Transplant Congress

    CT Based Anthropometric Visceral Fat Measures Predict Complexity, Complications and Low Clearance in Living Donor Nephrectomy

    Z. Ahmed,1 D. Bordom,1 J. Brown,1 B. Ridley,1 R. Uwechue,1 P. Chandak,1 N. Kessaris,1 N. Kurunanithy,2 N. Mamode.1

    1Abdominal Transplant, Guy's Hospital, London, United Kingdom; 2Clinical Radiology, Guy's Hospital, London, United Kingdom.

    Donor nephrectomy complexity, complications and residual renal function remain subject to large degrees of unexplained heterogeneity. This study assessed intrabdominal and perinephric fat content using…
  • 2018 American Transplant Congress

    Components of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBX) Impacting Late Death Censored Graft Failure (DCGF)

    J. Grande,1 L. Hunsicker,2 R. LeDuc,3 A. Matas,3 The DeKAF Consortium.

    1Pathology, Mayo Clinic, Rochester, MN; 2Int. Med., U Iowa, Iowa City, IA; 3Biostatistics and Surgery, U Minnesota, Minneapolis, MN.

    Recent studies document that MVI increases DCGF. However, the relationship between components of MVI (Banff scores g, cg, ptc) and macrovascular inflammation (v) have not…
  • 2018 American Transplant Congress

    The Influence Factors of DCD Donors' Family Members' Willingness in Chinese Current Status (Hunan Province Experience)

    B. Tu, C. Li, C. Li, S. Liu, Y. Zhao, X. She, Y. Ming.

    Transplantation Center of the 3rd Xiangya Hospital, Central South University, Changssha, Hunan, China.

    Background: Organ donation after citizen death (DCD) in China has developed gradually since the government promotes it powerfully from 2012, but the donation rate in…
  • 2018 American Transplant Congress

    FSGS Recurrence and Graft Survival in Pediatric Renal Transplants: A NAPRTCS Registry Analysis

    L. Koh,1 K. Martz,2 T. Blydt-Hansen.3

    1Starship Children's Health, Auckland, New Zealand; 2EMMES Corp., Rockville; 3BC Children's Hospital, Vancouver, Canada.

    IntroductionPrevious studies have raised concern of adverse outcome of living donor (LD) grafts in children transplanted for FSGS. This study reassesses impact of donor source,…
  • 2018 American Transplant Congress

    Racial and Ethnic Disparities in Preemptive Transplantation before and after the Introduction of Kidney Allocation System, in Pediatric and Young Adult End Stage Renal Disease Patients

    R. George,1 M. Basu,2 R. Garro,1 J. Hogan,1 R. Patzer.2

    1Pediatric Nephrology, Emory University & Children's Healthcare of Atlanta, Atlanta, GA; 2Dept of Surgery and Dept of Epidemiology, Emory University and Rollins School of Public Health, Atlanta, GA.

    Background: Among the various options of renal replacement therapy (RRT), preemptive transplantation (pTx) is the modality of choice in children. The objective of this study…
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