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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Impact of Total Graft Steatotic Mass in Liver Transplant Outcomes

    L. De Gregorio,1 E. Bugeaud,1 G. Galliano,2 H. Bohorquez,1 D. Bruce,1 I. Carmody,1 A. Cohen,1 J. Seal,1 D. Sonnier,1 A. Mathur,1 G. Loss.1

    1Abdominal Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; 2Pathology, Ochsner Clinic Foundation, New Orleans, LA.

    INTRODUCTIONGraft steatosis is a risk factor for early allograft dysfunction (EAD) and is thought to portend inferior transplant outcomes. The impact of total steatosis, combining…
  • 2018 American Transplant Congress

    Racial Differences in Patient-Perceived Barriers to Starting the Kidney Transplant Evaluation

    R. Hamoda, L. McPherson, K. Lipford, J. Gander, S. Pastan, R. Patzer.

    Emory University, Atlanta, GA.

    Overview: Racial disparities in access to kidney transplantation persist along multiple transplant steps, including start of the transplant evaluation. No studies have identified barriers that…
  • 2018 American Transplant Congress

    Racial Differences in Rates of Malignant and Infectious Cutaneous Genital Disease after Solid Organ Transplantation

    M. Larijani,1 K. Nadhan,1 J. Abbott,1 A. Doyle,2 C. Chung.1

    1Department of Dermatology, Drexel University, Philadelphia, PA; 2Department of Internal Medicine, University of Virginia, Charlottesville, VA.

    Purpose: To describe the prevalence and types of genital lesions observed in OTRsMethods: This retrospective review included 496 OTRs who underwent full skin examination at…
  • 2018 American Transplant Congress

    Outcomes of Enteric Conversion of Bladder Drained Pancreas; over a Decade of Experience at a Single Center

    S. Riad,1 D. Keys,1 V. Vakil,1 S. Jackson,2 D. Berglund,2 A. Matas,3 R. Kandaswamy.3

    1U of MN, Minneapolis; 2Fairview, Minneapolis; 3U of MN, Minneapolis.

    Background: Bladder drainage in pancreas transplantation has been used to enable early detection of rejection. This technique has declined due to concern over complications necessitating…
  • 2018 American Transplant Congress

    Ideal Body Weight versus Actual Body Weight for Rabbit Antithymocyte Globulin Induction in Pancreas Transplantation

    E. Martinez,1 D. Felix,2 J. Wiegel,2 T. Al-Qaoud,1 G. Leverson,1 A. Condon,2 R. Redfield,1 J. Odorico.1

    1Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Department of Pharmacy, UW Health, Madison, WI.

    Purpose: Rabbit antithymocyte globulin (rATG) is the most commonly used induction agent in solid organ pancreas transplantation. The optimal induction dosing of rATG, has not…
  • 2018 American Transplant Congress

    Increased Risk of Early Graft Loss in Pancreas Transplant: A Retrospective Review of the UNOS Database

    E. Steen,1 C. Liu,2 E. Siskind,2 J. Ortiz.1

    1Surgery, University of Toledo Medical Center, Toledo, OH; 2Surgery, Inova Fairfax Hospital, Annandale, VA.

    Introduction: Pancreas transplant is an established cure for Type 1 diabetes. Nonetheless, early graft loss is not infrequent. We sought to analyze all of the…
  • 2018 American Transplant Congress

    Implementing Mobile Health Technology for Living Kidney Donor Follow-Up: Transplant Provider Perspectives

    A. Eno,1 J. Ruck,1 S. Rasmussen,1 D. Segev,1,2 M. Henderson.1

    1Department of Surgery, Johns Hopkins School of Medicine, Baltimore; 2Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore.

    Transplant hospitals are required to collect and report living kidney donor (LKD) follow-up data at 6-months, 1-year, and 2-years, but fewer than 50% of hospitals…
  • 2018 American Transplant Congress

    Biomaterial-Based Localized and Controlled Delivery of Tofacitinib to Actuate Enhanced Costimulation Blockade and Promote Long-Term Transplant Survival

    G. Raimondi,1 P. Majumder,2 V. Ivanova,1 X. Calderon-Colon,3 A. Mirdad,1 M. Iglesias Lozano,1 W. Lee,1 G. Brandacher,1 J. Schneider,2 J. Patrone.3

    1Johns Hopkins School of Medicine, Baltimore; 2National Cancer Institute, Frederick; 3Johns Hopkins Applied Physics Laboratory, Laurel.

    Complications from long-term use of calcineurin inhibitors remain a major issue for transplant patients and alternative therapies are highly needed. We investigated two innovative drug…
  • 2018 American Transplant Congress

    T Cell Immunomonitoring Including Donor Specific Treg Expansion Prospectively Predicts Renal Allograft Tolerance Induced by Transient Mixed Chimerism

    K. Hotta, T. Oura, A. Dehnadi, K. Huh, M. Matsunami, H. Sasaki, G. Benichou, J. Madsen, A. Cosimi, T. Kawai.

    Center for Transplant Science, Massachusetts General Hospital, Boston, MA.

    Background: Successful induction of allograft tolerance in MHC-mismatched kidney transplantation has been achieved after induction of transient chimerism in both nonhuman primates (NHP) and humans.…
  • 2018 American Transplant Congress

    NOS2 Deficiency Limits Long Term Survival of Murine Kidney Allografts

    I. Aljabban,1,2 B. Jiang,1 C. Yang,1 T. O'Shea,1 D. Ndishabandi,1 R. White,1 P. Russell,1 R. Colvin,1 J. Madsen,1 A. Alessandrini.1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA; 2Pennsylvania State University College of Medicine, Hershey, PA.

    Nitric oxide (NO) is a small molecule derived from L-arginine that governs a myriad of physiologic processes including the antimicrobial and tumoricidal responses. Although NO…
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